Protein Alignment Menl-1 and Me3

DIOPT Version :10

• Sequence 1: NP_001027428.1
• Gene: Menl-1 / 3772542
• FlyBaseID: FBgn0029154
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_001402901.1
• Gene: Me3 / 361602
• RGDID: 1311070
• Length: 604
• Species: Rattus norvegicus
• Alignment Length: 554
• Identity: 251/554 - (45%)
• Similarity: 355/554 - (64%)
• Gaps: 7/554 - (1%)

  Fly    45 VPI-----EVVFSDKCNKALAFTLEERQRLCIHGLMPACVRTYDEQMLAIESNFHSFESNVGRYR 104
            ||:     :|..:...||.:|||||||.:|.||||:|.|..:.|.|:|.|...:.:.:|::.:|.
  Rat    44 VPLKKRGYDVTRNPHLNKGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYENQQSDLDKYI 108

  Fly   105 YLRALRQGYERLYFQFVSKNVHAVLPIIYTPTVGLACTVYGMLYRGMTGIHITKHDRGHMKQILS 169
            .|..|:...|:|:::.::.:|...:||:|||||||||..||:.:|...|:.||.||:||:..:|:
  Rat   109 ILMTLQDRNEKLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHIATMLN 173

  Fly   170 NWPMRRSVKAICVTDGQRILGLGDLGANGMGIAVGKMELYTALAGIPPSMLLPICLDVGTNNKSL 234
            :|| ..::||:.||||:|||||||||..||||.|||:.||||..|:.|...||:.|||||||:.|
  Rat   174 SWP-EDNIKAVVVTDGERILGLGDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEEL 237

  Fly   235 HEDPLYIGLRDERLKGDEYVCFVDEFMEAVVSTFGDQTLIHFEDFATPNAFMFLNRYQHCYCHFN 299
            ..|||||||:.:|::|.||...:||||:||...||...||.|||||..|||..||:|::.||.||
  Rat   238 LRDPLYIGLKHQRVRGKEYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKYCMFN 302

  Fly   300 DDIQGTAAVGLGGLLGIQRITKKPLEEHVIVFAGAGSAAMGIAYLLKMELMSRGLSEADAAKNIY 364
            |||||||:|.:.|:|...||||..|..||.||.|||.||||||:||.|.|...|:.:.:|.:.|:
  Rat   303 DDIQGTASVAVAGILAALRITKNRLSNHVFVFQGAGEAAMGIAHLLVMALEKEGIPKTEAVRKIW 367

  Fly   365 FYDQDGVLTTARKSIPDILCVFAKNMKETKSLETLVEQVKPSIIMGATSAPGLFTEKIIRTMAAS 429
            ..|..|::...|..:.....:||:...|..|||.:|..|||:.|:|..:..|.|||:|:|.||:.
  Rat   368 MVDSKGLIVKGRSHLNHEKEMFAQEHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASF 432

  Fly   430 HERPGIFAFSNPTIKSECTAEQAYKFSDGKAIYSAGSPFPPVEF-NGKRLTPGQANNCFAFPALV 493
            ||||.|||.||||.|:|||||:.|:.::|:.|:::||||..|.. :|:...|||.||.:.||.:.
  Rat   433 HERPIIFALSNPTSKAECTAEKCYQVTEGRGIFASGSPFKSVTLEDGRTFIPGQGNNAYVFPGVA 497

  Fly   494 LATMTVLATRMPDEIFLLAAHELAEFPTNEEMQSGRIYPLVKQANEVAYKIGVKVAKYLIENGYA 558
            |..:......:|||||||.|.::|:..:.:.:..||:||.:....:|:.:|.|||..|..::..|
  Rat   498 LGIIAGGIRHVPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAVKVLDYAYKHNLA 562

  Fly   559 KRNLEPEDVEEYIEKNSYKLTYGSSLAETWAYPK 592
            ....||:|.|.:|:...|...|.|...:|:.:||
  Rat   563 SYYPEPKDKEAFIKSLIYTPDYDSFSLDTYTWPK 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Menl-1	NP_001027428.1	PLN03129	35..582	CDD:215594	247/542 (46%)
Me3	NP_001402901.1	PLN03129	9..587	CDD:215594	247/543 (45%)