DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Menl-1 and SPAC750.08c

DIOPT Version :9

Sequence 1:	NP_001027428.1	Gene:	Menl-1 / 3772542	FlyBaseID:	FBgn0029154	Length:	610	Species:	Drosophila melanogaster
Sequence 2:	NP_595034.1	Gene:	SPAC750.08c / 2542710	PomBaseID:	SPAC750.08c	Length:	228	Species:	Schizosaccharomyces pombe

Alignment Length:	198	Identity:	64/198 - (32%)
Similarity:	100/198 - (50%)	Gaps:	6/198 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   389 NMKETKS----LETLVEQVKPSIIMGATSAPGLFTEKIIRTMAASHERPGIFAFSNPTIKSECTA 449
            :.||..|    |||.:..:||::::|.:..||.||||.||.|:...:.|.||..||||...|...
pombe    27 DFKEVPSGDIDLETAISLIKPTVLLGCSGQPGKFTEKAIREMSKHVKHPIIFPISNPTTLMEAKP 91

  Fly   450 EQAYKFSDGKAIYSAGSPFPPVEFNGKRLTPGQANNCFAFPALVLATMTVLATRMPDEIFLLAAH 514
            .|..::|:|||:.:.|||.||:..|||.....|.||...:|||.:|.:......:.|.:...|:.
pombe    92 VQIDEWSNGKALMATGSPLPPLTRNGKEYVISQCNNALLYPALGVACVLSRCKLLSDGMLKAASD 156

  Fly   515 ELAEFPTNEEMQSGRIYPLVKQANEVAYKIGVKVAKYLIENGYAKRNLEPED--VEEYIEKNSYK 577
            .||..|.:..:....:.|.:..|.|::..|...|.|..|..|.:..:|..:|  ::|:|.:..:.
pombe   157 ALATVPRSLFVADEALLPDLDNAREISRHIVFAVLKQAISEGMSTVDLPKDDAKLKEWIIEREWN 221

  Fly   578 LTY 580
            ..|
pombe   222 PEY 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Menl-1	NP_001027428.1	PLN03129	35..582	CDD:215594	64/198 (32%)
		malic	114..292	CDD:278802
		NAD_bind_1_malic_enz	302..576	CDD:133454	63/192 (33%)
SPAC750.08c	NP_595034.1	NADB_Rossmann	<1..222	CDD:304358	63/194 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	147	1.000	Domainoid score	I1122
eggNOG	1	0.900	-	-		E1_COG0281
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000475
OrthoInspector	1	1.000	-	-		mtm9297
orthoMCL	1	0.900	-	-		OOG6_100205
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.710