Protein Alignment Menl-1 and men-1

DIOPT Version :9

• Sequence 1: NP_001027428.1
• Gene: Menl-1 / 3772542
• FlyBaseID: FBgn0029154
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_496968.1
• Gene: men-1 / 175079
• WormBaseID: WBGene00012983
• Length: 620
• Species: Caenorhabditis elegans
• Alignment Length: 564
• Identity: 251/564 - (44%)
• Similarity: 357/564 - (63%)
• Gaps: 14/564 - (2%)

  Fly    47 IEVVFSDKCNKALAFTLEERQRLCIHGLMPACVRTYDEQMLAIESNFHSFESNVGRYRYLRALRQ 111
            |:::.|...||.:||:|.|||.|.:|||:|....|.::|...|.:.......|:.:|..|.:|:.
 Worm    52 IDLLKSPGLNKGMAFSLHERQYLGVHGLLPPAFMTEEQQAYRIITKLRQQPDNLAKYIQLDSLQD 116

  Fly   112 GYERLYFQFVSKNVHAVLPIIYTPTVGLACTVYGMLYRGMTGIHITKHDRGHMK--QILSNWPMR 174
            ..|:||::.:..||..::||:||||||.||..:|.:||...|::||.:|....|  |||:||| .
 Worm   117 RNEKLYYRVLCDNVKELMPIVYTPTVGQACQHFGFIYRNPKGLYITINDNSISKIHQILANWP-T 180

  Fly   175 RSVKAICVTDGQRILGLGDLGANGMGIAVGKMELYTALAGIPPSMLLPICLDVGTNNKSLHEDPL 239
            .:|:||.:|||:|||||||||..|:||.|||:.||.|||||.|...||:.|||||:|..|..||.
 Worm   181 ENVRAIVITDGERILGLGDLGTYGIGIPVGKLALYVALAGIRPEWCLPVILDVGTDNSELLNDPF 245

  Fly   240 YIGLRDERLKGDEYVCFVDEFMEAVVSTFGDQTLIHFEDFATPNAFMFLNRYQHCYCHFNDDIQG 304
            |.|||.:|::|.||...||.||:|....||..|||.||||...||:..|:||:..||.|||||||
 Worm   246 YTGLRRKRVRGPEYDTLVDNFMKAATKRFGRDTLIQFEDFGNQNAYRLLDRYKGEYCMFNDDIQG 310

  Fly   305 TAAVGLGGLLGIQRITKKPLEEHVIVFAGAGSAAMGIAYLLKMELMSRGLSEADAAKNIYFYDQD 369
            ||||.:.|||...|||||.|.:..|||.|||.||.|:|.:...::|..||||.:|...||..|.:
 Worm   311 TAAVVVAGLLASTRITKKKLSQERIVFLGAGGAATGVAEMCVRQMMDEGLSEEEACGRIYMVDIE 375

  Fly   370 GVLTTAR-KSIPDILCVFAKNMKETKSLETLVEQVKPSIIMGATSAPGLFTEKIIRTMAASHERP 433
            |::||:| ||:.:....|||::.:||:|..:|:.|||..::||::..|.|||.||:.||..:.||
 Worm   376 GLITTSRSKSLGERHVKFAKDLPDTKNLLEVVKTVKPGALIGASTVAGAFTEDIIKEMARLNPRP 440

  Fly   434 GIFAFSNPTIKSECTAEQAYKFSDGKAIYSAGSPFPPVEFNGKRLTPGQANNCFAFPALVLATMT 498
            .|||.||||.|:|||||.||:.::|..::::||||..||.|||...|||.||.:.||.:.|..:.
 Worm   441 IIFALSNPTSKAECTAETAYRCTNGAVLFASGSPFENVEMNGKLYKPGQGNNAYIFPGVALGAVL 505

  Fly   499 VLATRMPDEIFLLAAHELAEFPTNEEMQS-GRIYPLVKQANEVAYKIGVKVAKYLIENGYAKRNL 562
            .....:||::|||||..:||..:.:.:.: .|:||.:|...|::.||.|:|.:|...:..|..:.
 Worm   506 FRTKNIPDKLFLLAARMVAEAVSEKSLNTYSRVYPRLKDIRELSVKIAVEVGEYCYRHDLATLHP 570

  Fly   563 EPEDVEEYIEKNSYKLTYGSSLAETWAYPKMKPHPSTAGHENKH 606
            :|:|:|.:|.:|.|.:.|...:.:|:.:|         ..::||
 Worm   571 KPDDMEMFIRQNLYSVEYDELINKTYEWP---------AKDSKH 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Menl-1	NP_001027428.1	PLN03129	35..582	CDD:215594	247/538 (46%)
		malic	114..292	CDD:278802	95/179 (53%)
		NAD_bind_1_malic_enz	302..576	CDD:133454	121/275 (44%)
men-1	NP_496968.1	PLN03129	46..592	CDD:215594	247/540 (46%)
		malic	115..298	CDD:278802	95/183 (52%)
		Malic_M	308..560	CDD:281882	114/251 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166735
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0281
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60768
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000475
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100205
Panther	1	1.100	-	-	O	PTHR23406
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X340
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.750