Protein Alignment Menl-1 and Me3

DIOPT Version :10

• Sequence 1: NP_001027428.1
• Gene: Menl-1 / 3772542
• FlyBaseID: FBgn0029154
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_852072.2
• Gene: Me3 / 109264
• MGIID: 1916679
• Length: 604
• Species: Mus musculus
• Alignment Length: 597
• Identity: 260/597 - (43%)
• Similarity: 372/597 - (62%)
• Gaps: 16/597 - (2%)

  Fly    10 GITRGSSISKTHQSNCECSPNLIKIRPSS--------SHDTIRVPI-----EVVFSDKCNKALAF 61
            |...|:....|......|| :|.:..||:        |.....||:     :|..:...||.:||
Mouse     2 GAALGTGARLTSVPRIACS-SLRRQAPSAPAQGCHSKSGPPRPVPLKKRGYDVTRNPHLNKGMAF 65

  Fly    62 TLEERQRLCIHGLMPACVRTYDEQMLAIESNFHSFESNVGRYRYLRALRQGYERLYFQFVSKNVH 126
            |||||.:|.||||:|.|..:.|.|:|.|...:.:.:|::.:|..|..|:...|:|:::.::.:|.
Mouse    66 TLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYENQQSDLDKYIILMTLQDRNEKLFYRVLTSDVE 130

  Fly   127 AVLPIIYTPTVGLACTVYGMLYRGMTGIHITKHDRGHMKQILSNWPMRRSVKAICVTDGQRILGL 191
            ..:||:|||||||||..||:.:|...|:.||.||:||:..:|::|| ..::||:.||||:|||||
Mouse   131 KFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHIATMLNSWP-EDNIKAVVVTDGERILGL 194

  Fly   192 GDLGANGMGIAVGKMELYTALAGIPPSMLLPICLDVGTNNKSLHEDPLYIGLRDERLKGDEYVCF 256
            ||||..||||.|||:.||||..|:.|...||:.|||||||:.|..|||||||:.:|::|:||...
Mouse   195 GDLGCYGMGIPVGKLALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVRGEEYDDL 259

  Fly   257 VDEFMEAVVSTFGDQTLIHFEDFATPNAFMFLNRYQHCYCHFNDDIQGTAAVGLGGLLGIQRITK 321
            :||||:||...||...||.|||||..|||..||:|::.||.|||||||||:|.:.|:|...||||
Mouse   260 LDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKYCMFNDDIQGTASVAVAGILAALRITK 324

  Fly   322 KPLEEHVIVFAGAGSAAMGIAYLLKMELMSRGLSEADAAKNIYFYDQDGVLTTARKSIPDILCVF 386
            ..|..||.||.|||.||||||:||.|.|...|:.:.:|.|.|:..|..|::...|..:.....:|
Mouse   325 NRLSNHVFVFQGAGEAAMGIAHLLVMALEKEGIPKTEAIKKIWMVDSKGLIVKGRSHLNHEKEMF 389

  Fly   387 AKNMKETKSLETLVEQVKPSIIMGATSAPGLFTEKIIRTMAASHERPGIFAFSNPTIKSECTAEQ 451
            |::..|..|||.:|..|||:.|:|..:..|.|||:|:|.||:.||||.:||.||||.|:|||||:
Mouse   390 AQDHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIVFALSNPTSKAECTAEK 454

  Fly   452 AYKFSDGKAIYSAGSPFPPVEF-NGKRLTPGQANNCFAFPALVLATMTVLATRMPDEIFLLAAHE 515
            .|:.::|:.|:::||||..|.. :|:..||||.||.:.||.:.|..:......:|||||||.|.:
Mouse   455 CYRVTEGRGIFASGSPFKSVTLEDGRTFTPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQ 519

  Fly   516 LAEFPTNEEMQSGRIYPLVKQANEVAYKIGVKVAKYLIENGYAKRNLEPEDVEEYIEKNSYKLTY 580
            :|:..:.:.:..||:||.:....:|:.:|.|||..|..::..|....||:|.|.:::...|...|
Mouse   520 IAQEVSEQHLSQGRLYPPLSTIRDVSLRIAVKVLDYAYKHNLASYYPEPKDKEAFVKSLIYTPDY 584

  Fly   581 GSSLAETWAYPK 592
            .|...:|:::||
Mouse   585 DSFSLDTYSWPK 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Menl-1	NP_001027428.1	PLN03129	35..582	CDD:215594	250/560 (45%)
Me3	NP_852072.2	PLN03129	9..587	CDD:215594	254/579 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	28..50		4/21 (19%)