DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11889 and CG6830

DIOPT Version :9

Sequence 1:	NP_001287526.1	Gene:	CG11889 / 3772506	FlyBaseID:	FBgn0039308	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster

Alignment Length:	432	Identity:	115/432 - (26%)
Similarity:	202/432 - (46%)	Gaps:	30/432 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PE-KTTHN--APAWLTEEYVEKKLRVYFKNDTLNLKKLT---IKPATANGENYASVMTRISVEYI 60
            || :..|:  .|.||.:...|:.|..    |.....|:.   :|||.|.|||||::|.|||::..
  Fly    36 PEPEVDHSDLVPKWLNQTQFEELLAA----DVDQFSKIVGFRVKPAMAPGENYATLMLRISIDVE 96

  Fly    61 TKDSKDNQSATFLLKTTFADKDPAAHLLINYGIYTREIDMYEQILPRLADIVKNELHDSR----- 120
            ..| |..:..:|::|... |......::.....:|.|...|.:|||::.::.|.:..|.:
  Fly    97 LTD-KSTKLVSFMMKVPH-DTPQMEQMMSMANFFTSENAAYTEILPKMEELYKAKGLDIKFAPRA 159

  Fly   121 -KLFAATVGVDRERDSIMFEDLSLERYKVACRVKKLDLEHTYLVLEKLADFHAAGAALAQ---RQ 181
             ||.|..  ..:..::::..||....:|...|::.|:||.|...|.:||.||||||.:.|   ..
  Fly   160 FKLDATK--EPKVANTVLMHDLGQNGFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQVHGPY 222

  Fly   182 PGIFEKNYDRGFFNKHVRGYEPIMKNILKALSRTLDLSPDL---KERYQAKIDRLIDNVMDYGER 243
            |.||.    .|....:.......|:.:|.:...:...:.|.   .|.|:.|:::.:..:.....:
  Fly   223 PDIFV----NGVMGNNKEAIIAFMEGMLASFRTSFMANLDKFKNGEEYREKLEKALAGLTMEFMK 283

  Fly   244 STSVAPGDFVTLAHGDIWTTNVMFQYDDEGHPVNAIFIDFQFSVWNSPAIDLQYFFSTSIHENLR 308
            ...|.|.:|..|.|||.|..|::|:.:..|...:.:|:|||...:.|||:||.||..:|:..:.:
  Fly   284 LGIVDPNEFNALNHGDCWMNNLLFKMNSSGDLEDMVFVDFQNPKYGSPAMDLLYFIISSVQIDYK 348

  Fly   309 LERQTELVQFYFYKLVVALERVKYSGKVPSLFEFQQQFRTKGFYAVFASLIFEPTMVYNGKEEPS 373
            |......::.|...||..|..:.::|:.|||.|..:.....|.:.:|.::...|.::.:..:..:
  Fly   349 LSHFDFFIRHYQEALVKHLGILGFTGRKPSLRELHRTLIKYGGWVLFPTISVLPLVLLDPTQSAT 413

  Fly   374 IEQFMTSDEKGVRLRDAVYQTEENLKKLHLTLPFLDQLGLLD 415
            .:.||:....||..|.::|..:...:.:...||:||..|.|:
  Fly   414 FDNFMSDSADGVSFRGSLYANKRCQEYIERILPWLDNRGFLE 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11889	NP_001287526.1	EcKinase	44..332	CDD:281023	81/299 (27%)
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	81/299 (27%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459372
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940