DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11889 and CG33511

DIOPT Version :9

Sequence 1:	NP_001287526.1	Gene:	CG11889 / 3772506	FlyBaseID:	FBgn0039308	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_001014492.2	Gene:	CG33511 / 3346223	FlyBaseID:	FBgn0053511	Length:	415	Species:	Drosophila melanogaster

Alignment Length:	361	Identity:	75/361 - (20%)
Similarity:	147/361 - (40%)	Gaps:	20/361 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 KNDTLNLKKLTIKPATANGENYASVMTRISVEYITKDSKDNQSATFLLKTTFADKDPAAHLLINY 91
            |.|.:.|....:...:.:...|.....::.:|...|..|......:.:|:.....:|........
  Fly    21 KKDNVILINSQVDAGSKDLMGYMGEYYKLHLEAEVKGDKKKYFLNYFIKSLPRKNEPQREECERK 85

  Fly    92 GIYTREIDMYEQILPRLADIVKNELHDSRKLFAATVGVDRERDSIMFEDLSLERYKVACRVKKLD 156
            |::.:|..:|.||||::......:|:.  |.:.:      ..|.::.|||: :.|:.....:...
  Fly    86 GVFQKESALYSQILPKIQKYATKKLYP--KCYYS------RNDILVLEDLT-QDYRHLRANEYYT 141

  Fly   157 LEHTYLVLEKLADFHAAGAALAQRQPGIFEKNYDRGFFNKHVRGYEPIMKNILKALSRTLDLSPD 221
            |:|..:|||.|::.|||..|..:::.....::|.......|:..........|||:......:|.
  Fly   142 LDHYKIVLEHLSELHAASIAWEEKENVKIYESYKNVLIELHLDSNNSWYITGLKAIVFLAARNPH 206

  Fly   222 LKE-RYQAKIDRLIDNVMDYGERSTSVAPGDFV--TLAHGDIWTTNVMFQYDDEGH--PVNAIFI 281
            .:. :.|..|...:.|::...|.  .|||...:  .|.|.|.|..|:::.::.|..  |.....:
  Fly   207 FQTMKAQNFIQDKLYNLLTKAEE--LVAPSKTIRNVLCHRDTWDHNIVYYFNKESSVLPNACCIV 269

  Fly   282 DFQFSVWNSPAIDLQYFFSTSIHENLRLERQTELVQFYFYKLVVALERVKYSGKVPSLFEFQQQF 346
            |||.:.:.||.:|:.:.........:|.....|.::.|:..|...|:|:.....:.:...|:::.
  Fly   270 DFQLTQYCSPTLDVLFLLYIVASAEVRRAIYDECLEHYYKNLQHHLDRLGLDKNLITENNFRKEC 334

  Fly   347 RTKGFYAVFASLIFEPTMVYNGKEEPSIEQFMTSDE 382
            :.....|:....:.||    ..|..|||...:.|:|
  Fly   335 QRTRLAALVIWALTEP----QTKMSPSISNRLRSEE 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11889	NP_001287526.1	EcKinase	44..332	CDD:281023	62/292 (21%)
CG33511	NP_001014492.2	PKc_like	41..319	CDD:304357	62/288 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459493
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940