DRSC/TRiP Functional Genomics Resources

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Protein Alignment Indy-2 and PHO87

DIOPT Version :10

Sequence 1:NP_001027201.1 Gene:Indy-2 / 3772456 FlyBaseID:FBgn0260466 Length:562 Species:Drosophila melanogaster
Sequence 2:NP_009966.2 Gene:PHO87 / 850403 SGDID:S000000633 Length:923 Species:Saccharomyces cerevisiae


Alignment Length:549 Identity:113/549 - (20%)
Similarity:209/549 - (38%) Gaps:150/549 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 GKASIIIPLITLPI-LIYGFQT--DMAEFKCLWLIVTMALLWITETLPIYVTALF-PLVFC---- 78
            ||.::.|..|.:.. ::.|.:|  |..|.:|:.|:...|.||.:|.:|:::|.|. ||:..    
Yeast   456 GKRAMKIGFIIIVTGVLLGVKTFNDPVEHRCMALVECCAFLWASEAIPLHITGLLVPLLTVLFRV 520

  Fly    79 ------PLLGLVNASI-VCKQYFTDTIVVFLGGLIVALGIEYSNLHTRIALRVIRIVGGSPRRLF 136
                  .::|...||. :....::.||::.|.|..:...:...|:...:|..::.:.|..||.:.
Yeast   521 LKDDDGKVMGAAAASTEILGTMWSSTIMILLAGFTLGEALSQYNVAKVLASWLLALAGTKPRNVL 585

  Fly   137 VGLMSVSTFMGLWISNSAGTAMMCPIVKALVNELDTNKIFPVYMTQEEEPVEEGEPPHPSKITVA 201
            :..|||..|:.:||||.|...:...::..|::.||                      :.|....|
Yeast   586 LMAMSVVFFLSMWISNVASPVLTYSLLTPLLDPLD----------------------YTSPFAKA 628

  Fly   202 FYAGIAYASSIGGLGTLIGTGTNLVFRGIYTERFPTSTVEITFANFMFYSIP---LMVIVNVTLV 263
            ...|:|.::.|||:.:.|.:..|::... |.:.:     .|.:..|...::|   |.::.:..|:
Yeast   629 LVMGVALSADIGGMASPISSPQNIISMQ-YLKPY-----GIGWGQFFAVALPTGILSMLCSWALM 687

  Fly   264 IIAFLI--THMGLFRPNSKTGKIIAEANTNRKLMEDVLRQRHIDLGPMS-----CHEIQMAIAFA 321
            |:.|.|  |.:..|:|       |....|        ::|..|.:..::     |.|.|:..|| 
Yeast   688 ILTFKIGKTKLEKFKP-------IRTRFT--------IKQYFIIIVTIATILLWCVESQIESAF- 736

  Fly   322 FMIVLLITRKPGFVPGWSDLINRKVVGSASGLSFIVLLIFALPTQYTFFKYCCGKGPFTAQAIDA 386
                                      ||:..::.|.:::|            .|.|..:.:..: 
Yeast   737 --------------------------GSSGEIAVIPIVLF------------FGTGLLSTKDFN- 762

  Fly   387 ILSWEYVLRNIPWGLLFLLGGGFALAVASRETGLNIMISKAMQVLIGLPNI-VVQSITFVLANFF 450
                     ..||.::.|..||.||..|...:||.:.|::|:|..|....: .:..|..:|....
Yeast   763 ---------TFPWSIVVLAMGGIALGKAVSSSGLLVTIARALQKKIQNDGVFAILCIFGILMLVV 818

  Fly   451 SAFNANVVVANIVLPILCEMSLALELHPLILTLPACLGISMVYFLPVSTPPNAIVTQYAHIKTKY 515
            ..|.::.|.|.|::|::.|:...|                       |.|..|.:..:.   ...
Yeast   819 GTFVSHTVSAIIIIPLVQEVGDKL-----------------------SDPKAAPILVFG---CAL 857

  Fly   516 FACCGI------VPTIIGISVALVNTNTW 538
            .|.||:      .|.:..||:.....|.|
Yeast   858 LASCGMGLASSGFPNVTAISMTDKKGNRW 886

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Indy-2NP_001027201.1 CitT 102..544 CDD:440239 89/454 (20%)
PHO87NP_009966.2 COG5408 1..334 CDD:227695
SLC13_permease 487..914 CDD:238535 104/518 (20%)
Blue background indicates that the domain is not in the aligned region.

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