Protein Alignment Indy-2 and slc13a3

DIOPT Version :9

• Sequence 1: NP_001027201.1
• Gene: Indy-2 / 3772456
• FlyBaseID: FBgn0260466
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: XP_031749933.1
• Gene: slc13a3 / 548493
• XenbaseID: XB-GENE-5765054
• Length: 602
• Species: Xenopus tropicalis
• Alignment Length: 601
• Identity: 202/601 - (33%)
• Similarity: 310/601 - (51%)
• Gaps: 70/601 - (11%)

  Fly     8 RKFVLGRCCIFHWRGKASIIIPLITLPILIYGFQTDMAEFKCLWLIVTMALLWITETLPIYVTAL 72
            ||:|:            .|..|||.||:|   |.....|.|||::::.||..|.||.||:.||||
 Frog    15 RKYVI------------LIATPLILLPVL---FSLPPKEGKCLFVVLLMAFYWCTEALPLAVTAL 64

  Fly    73 FPLVFCPLLGLVNASIVCKQYFTDTIVVFLGGLIVALGIEYSNLHTRIALRVIRIVGGSPRRLFV 137
            .|:|..||||::.:|.||.|||.||..:||.||::|..||..|||.||||:|:.:||..|.||.:
 Frog    65 LPIVLFPLLGILPSSKVCPQYFLDTNFLFLSGLLMAAAIEEWNLHRRIALKVLTLVGVQPARLIL 129

  Fly   138 GLMSVSTFMGLWISNSAGTAMMCPIVKALVNEL-------------------------------- 170
            |:|..:.|:.:|:||:|.||||.||..|::..|
 Frog   130 GMMMTTAFLSMWLSNTASTAMMLPIANAILKSLYGERSSKEKGLNNNCDSTASIQEKGLHPVPTE 194

  Fly   171 -------DTNKIFP--VYMTQEEEPVEEGEPPHPSKITVAFYAGIAYASSIGGLGTLIGTGTNLV 226
                   :.||..|  :.:..:..|..:.|..:.::|..||...|.|::||||..||.||..||:
 Frog   195 MQLLAANEENKDLPEKIDIPTDTHPDLQKEKEYQNRIWKAFLISIPYSASIGGTATLTGTAPNLI 259

  Fly   227 FRGIYTERFPTSTVEITFANFMFYSIPLMVI-VNVTLVIIAFLITHMGLFRPNSKTGKIIAEANT 290
            ..|.....||...| :.|.::..::.|||:: :.|..:.|:.|...:.|.....|...|.:||.:
 Frog   260 LLGQLKSFFPGCDV-VNFGSWFAFAFPLMILFLFVGWLWISVLHGAISLRCKRKKKSDIRSEAES 323

  Fly   291 NRKLMEDVLRQRHIDLGPMSCHEIQMAIAFAFMIVLLITRKPGFVPGWSDLINRKVVGSA-SGLS 354
            ..|   |::::.:..|||.:..|..:.:.|....:||.||.|.|:|||:..........| :|:|
 Frog   324 KAK---DIIQEDYRKLGPTNFAEKSVFVFFCLFAILLFTRDPKFIPGWASAFTPGFTSDAVTGIS 385

  Fly   355 FIVLLIFALPTQYTFFKYCCG-KGPFTAQAIDAILSWEYVLRNIPWGLLFLLGGGFALAVASRET 418
            ..::|.| .|::....|:... |.|.|..  .|:|||:.....:||.::.|||||||:|.....:
 Frog   386 ICIVLFF-FPSEKPSLKWWFDLKAPNTEN--KALLSWKKAQSTVPWNIILLLGGGFAMAKGCEVS 447

  Fly   419 GLNIMISKAMQVLIGL-PNIVVQSITFVLANFFSAFNANVVVANIVLPILCEMSLALELHPLILT 482
            ||:..|...:|.|.|: |.:.|..:|.::|: |:.|.:|.....:.||||.|:::.|:::||.|.
 Frog   448 GLSTWIGSRLQPLEGISPALAVLLVTVLIAS-FTEFASNTATIIVFLPILSELAIRLKVNPLYLM 511

  Fly   483 LPACLGISMVYFLPVSTPPNAIVTQYAHIKTKYFACCGIVPTIIGISVALVNTNTWGLIIFPESK 547
            :|..:|.|..:.||||||||:|.....|:..|..|..|:|..::|:.:..:..|||...|| :..
 Frog   512 VPGTVGCSYAFMLPVSTPPNSIAFSTGHLMVKDMAKTGLVMNLMGVLLLSLAMNTWATSIF-QLG 575

  Fly   548 SFPDWA-KEIKNQTKI 562
            :.|||. ..|.|.|::
 Frog   576 TIPDWVPSHIYNVTEL 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Indy-2	NP_001027201.1	ArsB_NhaD_permease	50..533	CDD:304373	177/527 (34%)
		dass	52..532	CDD:273267	176/524 (34%)
slc13a3	XP_031749933.1	ArsB_NhaD_permease	9..567	CDD:419678	192/574 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	357	1.000	Domainoid score	I978
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	369	1.000	Inparanoid score	I2088
OMA	1	1.010	-	-		QHG57284
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000298
OrthoInspector	1	1.000	-	-		mtm9386
Panther	1	1.100	-	-	O	PTHR10283
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X273
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.070