Protein Alignment Indy-2 and slc13a2

DIOPT Version :9

• Sequence 1: NP_001027201.1
• Gene: Indy-2 / 3772456
• FlyBaseID: FBgn0260466
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_998617.2
• Gene: slc13a2 / 406537
• ZFINID: ZDB-GENE-040426-2389
• Length: 613
• Species: Danio rerio
• Alignment Length: 622
• Identity: 200/622 - (32%)
• Similarity: 316/622 - (50%)
• Gaps: 98/622 - (15%)

  Fly     8 RKFVLGRCCIFHWRGKASIIIPLITLPILIYGFQTDMAEFKCLWLIVTMALLWITETLPIYVTAL 72
            |.::|..|            :||:.||:.:.   ....|.:|.:.|:.|||.|.||.:|:.:|||
Zfish    17 RNYILILC------------VPLLILPLPLV---LPTPEARCGFAIILMALFWCTECMPLAITAL 66

  Fly    73 FPLVFCPLLGLVNASIVCKQYFTDTIVVFLGGLIVALGIEYSNLHTRIALRVIRIVGGSPRRLFV 137
            .|:|..|::|::.:..||.||..||.::|:|||:||:.:|:.|||.||||.|:.:||..|..|.:
Zfish    67 LPVVLFPMMGIMESGKVCVQYLKDTNMLFIGGLLVAIAVEHWNLHKRIALSVLLVVGVRPALLML 131

  Fly   138 GLMSVSTFMGLWISNSAGTAMMCPIVKALVNEL---------------DTNKIF---------PV 178
            |.|.|:.|:.:||||:|.||||.||.:|::.:|               ..|:.|         |:
Zfish   132 GFMIVTAFLSMWISNTATTAMMLPISQAVLEQLSATEADSDEKELREGQVNQAFELTEVNIKQPL 196

  Fly   179 YMTQEEEP-----VEEG--------EPPHPSKITVAFYA---GIAYASSIGGLGTLIGTGTNLVF 227
            ..||.|:|     ||||        .....:|....|..   .:.|::||||..||.||..||:.
Zfish   197 DNTQGEKPNNNADVEEGINALSERRRKAREAKYLRLFKGMSLSVCYSASIGGTATLTGTTPNLIL 261

  Fly   228 RGIYTERFPTSTVEITFANFMFYSIPLMVIVNVTLVIIAFL---ITHMGLFRPNSKTGKIIAEAN 289
            :|...|.||.:...|.||::..::.|.||:    ::::::|   ..::|.   |.|........|
Zfish   262 KGQMDEIFPDNNDVINFASWFGFAFPNMVL----MLVLSWLWLQCMYLGF---NFKQSFGCGTKN 319

  Fly   290 TNRKLMEDVLRQRHIDLGPMSCHEIQMAIAFAFMIVLLITRKPGFVPGW-SDLINR--KVVGSAS 351
            ...|....|::..:..|||||..|..:.:.|.|:::|..||:|||:||| ::|.|:  :.|...:
Zfish   320 EGDKDAYKVMKNEYKKLGPMSFAEGAVLVIFIFLVILWFTREPGFMPGWATELFNKNGQYVTDGT 384

  Fly   352 GLSFIVLLIFALPTQYTFFKYCCGKGPFTAQAIDAI---------------------LSWEYVLR 395
            ...|:..|.|.:|::..|.  |..|  :..|..:|:                     |:|:.|..
Zfish   385 VAIFMSTLFFVIPSRVDFL--CSIK--YEEQDEEAVGEEQDGVEKEKKRKLKGTPTLLNWKVVHE 445

  Fly   396 NIPWGLLFLLGGGFALAVASRETGLNIMISKAMQVLIGLPNIVVQSITFVLANFFSAFNANVVVA 460
            .:||.::.|||||||||..|.|:||::.:.:::..|..:|...:..|..:|...|:..::|....
Zfish   446 RMPWNIVLLLGGGFALASGSEESGLSVWLGQSLSPLKSIPPFAISIILCLLVGTFTECSSNTATT 510

  Fly   461 NIVLPILCEMSLALELHPLILTLPACLGISMVYFLPVSTPPNAIVTQYAHIKTKYFACCGIVPTI 525
            .:.||||..|:..:.||||.:.||..:..|:.:.|||:||||||...|.::|....|..|.:..|
Zfish   511 TLFLPILASMATTIGLHPLYVMLPCTISASLAFMLPVATPPNAIAFSYGNLKVLDMAKAGFILNI 575

  Fly   526 IGISVALVNTNTWGLIIFPESKSFPDWAKEIKNQTKI 562
            |||....:..||||:.:| :..:||.||    |.|.:
Zfish   576 IGILCINLGINTWGMAMF-KLDTFPSWA----NNTLV 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Indy-2	NP_001027201.1	ArsB_NhaD_permease	50..533	CDD:304373	180/549 (33%)
		dass	52..532	CDD:273267	180/546 (33%)
slc13a2	NP_998617.2	ArsB_NhaD_permease	40..595	CDD:304373	187/566 (33%)
		dass	45..588	CDD:273267	181/553 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580414
Domainoid	1	1.000	381	1.000	Domainoid score	I793
eggNOG	1	0.900	-	-		E1_COG0471
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	396	1.000	Inparanoid score	I1908
OMA	1	1.010	-	-		QHG57284
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000298
OrthoInspector	1	1.000	-	-		mtm6448
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10283
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X273
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.900