Protein Alignment Indy-2 and slc13a3

DIOPT Version :10

• Sequence 1: NP_001027201.1
• Gene: Indy-2 / 3772456
• FlyBaseID: FBgn0260466
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_998067.1
• Gene: slc13a3 / 405838
• ZFINID: ZDB-GENE-040426-2486
• Length: 596
• Species: Danio rerio
• Alignment Length: 586
• Identity: 193/586 - (32%)
• Similarity: 295/586 - (50%)
• Gaps: 68/586 - (11%)

  Fly    20 WRGKASIII---PLITLPILIYGFQTDMAEFKCLWLIVTMALLWITETLPIYVTALFPLVFCPLL 81
            |..:..:|:   ||:.||:|   |.....|.|||::::.||:.|.||.||:.|||:.|:...|.:
Zfish    11 WCARQQLILVLAPLLLLPLL---FVVPPKEGKCLYVVLLMAVYWCTEALPLAVTAMLPVCLFPTM 72

  Fly    82 GLVNASIVCKQYFTDTIVVFLGGLIVALGIEYSNLHTRIALRVIRIVGGSPRRLFVGLMSVSTFM 146
            |::.:..||.|||.:|..:||.||::|..||...||.||||:|::|||..|..|.:|:|..|:|:
Zfish    73 GILPSKKVCPQYFLETNFLFLSGLVMASAIEEWGLHRRIALKVLKIVGVKPAWLILGMMITSSFL 137

  Fly   147 GLWISNSAGTAMMCPIVKALVNELDTN----------------------KIFP--VYMTQEEEP- 186
            .:|:||:|.||||.||..|::..|..|                      .:.|  ..:|.|:.|
Zfish   138 SMWLSNTATTAMMLPIANAILESLFGNLETLKENCKTRSDPEGDSQVKMHVLPEKQILTVEDRPD 202

  Fly   187 ---------VEE--GEPPHPSKITVAFYAGIAYASSIGGLGTLIGTGTNLVFRGIYTERFPTSTV 240
                     .||  .|..:..|:...|...|.||:||||..||.||..||:..|.....||...:
Zfish   203 WTDRSEQRNQEEVRREAEYQMKVWKGFLICIPYAASIGGTATLTGTAPNLILVGQLKSYFPECDL 267

  Fly   241 EITFANFMFYSIPLMVIVNVT-LVIIAFLI----THMGLFRPNSKTGKIIAEANTNRKLMEDVLR 300
             :.|.::..::.|||::..:. .:.||||.    |.:.:.:.:.:..   |||..|..:.||..:
Zfish   268 -VNFGSWFVFAFPLMLLFLILGWIWIAFLYGGLNTRLCISKNDERAA---AEAKANAVIDEDYKK 328

  Fly   301 QRHIDLGPMSCHEIQMAIAFAFMIVLLITRKPGFVPGWSDLINRKVVGSASGLSFIVLLIFALPT 365
                 |||:...|..:|..|....:||.||.|.||.|||....:..|..|.....|:.::|..|:
Zfish   329 -----LGPIKFAEGSIAFFFIIFAILLFTRDPKFVTGWSVFFPKGYVSDAVTGVIIISILFFFPS 388

  Fly   366 QYTFFKYCCGKGPFTAQAIDA----ILSWEYVLRNIPWGLLFLLGGGFALAVASRETGLNIMISK 426
            |....::.     |.::|.:.    :|||......:||.::.|||||||:|....|:||.:.|..
Zfish   389 QRPSLRWW-----FDSRASNTPYVPLLSWRKAQECVPWNIILLLGGGFAMAKGCEESGLAVWIGN 448

  Fly   427 AMQVLIGL-PNIVVQSITFVLANFFSAFNANVVVANIVLPILCEMSLALELHPLILTLPACLGIS 490
            .:|.|..: |.:.|..||..:| .|:.|.:|.....|.||::.|:::.::::||...:||..|.|
Zfish   449 HLQPLAQVPPPVAVMLITAFIA-CFTEFASNTATIIIFLPVIAELAIRVKVNPLYFMIPATTGCS 512

  Fly   491 MVYFLPVSTPPNAIVTQYAHIKTKYFACCGIVPTIIGISVALVNTNTWGLIIFPESKSFPDWAKE 555
            ..:.||||||||:|.....|:..|.....|.|..|:||....:..|||.|.:| ....:||||:.
Zfish   513 YAFMLPVSTPPNSIAFASGHLMVKDMVKTGFVMNILGILCVSLAMNTWALHMF-NLHLYPDWARP 576

  Fly   556 I 556
            :
Zfish   577 L 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Indy-2	NP_001027201.1	CitT	102..544	CDD:440239	156/487 (32%)
slc13a3	NP_998067.1	CitT	93..560	CDD:440239	153/481 (32%)