Protein Alignment Indy-2 and Slc13a5

DIOPT Version :10

• Sequence 1: NP_001027201.1
• Gene: Indy-2 / 3772456
• FlyBaseID: FBgn0260466
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: XP_017170015.1
• Gene: Slc13a5 / 237831
• MGIID: 3037150
• Length: 610
• Species: Mus musculus
• Alignment Length: 546
• Identity: 174/546 - (31%)
• Similarity: 284/546 - (52%)
• Gaps: 47/546 - (8%)

  Fly     4 PGEQRKFVL-----GRCCIFHWRGKASIII-PLITLPILIYGFQTDMAEFKCLWLIVTMALLWIT 62
            |||..:...     .:.|:..::..|.::. |::.||::|. .....|  :|.::||.||:.|.|
Mouse    27 PGESSQSPFHAMDSAKTCVTKFKSFAILLFTPILMLPLVIL-IPDKFA--RCAYVIVIMAVYWCT 88

  Fly    63 ETLPIYVTALFPLVFCPLLGLVNASIVCKQYFTDTIVVFLGGLIVALGIEYSNLHTRIALRVIRI 127
            :.:|:.||:|.|::..|||.::::..||.||..||.::|||.||||:.:|...||.|:|||::..
Mouse    89 DVIPVAVTSLLPVLLFPLLKVLDSKQVCIQYMKDTNMLFLGSLIVAVAVERWKLHKRVALRMLLF 153

  Fly   128 VGGSPRRLFVGLMSVSTFMGLWISNSAGTAMMCPIVKALVNE-----------------LDTNKI 175
            ||..|.||.:|.|.|:.|:.:||||:|.||||.|||:|::.:                 ||.||.
Mouse   154 VGTKPSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAANTAVEASLGTLELLDKNKT 218

  Fly   176 FPVYMTQ---EEEPVEEGEPPHPSKITVAFYAGIAYASSIGGLGTLIGTGTNLVFRGIYTERFPT 237
            ..:..:|   |:..|:|.|......:..|.:..:.|::||||..||.|||.|:|..|...|.||.
Mouse   219 SELPGSQVVFEDPNVQEQEDEETKNMYKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELFPD 283

  Fly   238 STVEITFANFMFYSIPLMVIVNVTLVIIAFLITHMGLFRPNSKTGKIIA--EANTNRKLMEDVLR 300
            |...:.:|::..::.|.||:    ::::|:|.......|.|.|...|..  :.....|:...||.
Mouse   284 SKDVLNYASWFGFAFPNMVM----MLVLAWLWLQCLYMRHNLKKTCICCGEKKRDTEKIAYKVLN 344

  Fly   301 QRHIDLGPMSCHEIQMAIAFAFMIVLLITRKPGFVPGWSDLI----NRKVVGSASGLSFIVLLIF 361
            :.:..||.:|..|..:...|..:::|..:|.|||:|||....    |...:..|:...|:.:|:|
Mouse   345 EEYQKLGSLSYPECNVLFCFTLLVILWFSRDPGFMPGWLSFAWVEGNTVHITDATVAIFVAILLF 409

  Fly   362 ALPTQYTFFKYCC-----GKGPFTAQAIDAILSWEYVLRNIPWGLLFLLGGGFALAVASRETGLN 421
            .:|:|...|.:..     .|.||..   .|:|.|:.....:||.::.|||||||:|.....:||:
Mouse   410 IIPSQKPKFNFSSQTEEERKTPFYP---PALLDWKVAQEKVPWDIVLLLGGGFAMAKGCETSGLS 471

  Fly   422 IMISKAMQVLIGLPNIVVQSITFVLANFFSAFNANVVVANIVLPILCEMSLALELHPLILTLPAC 486
            ..::..|:.|..:...|:..|...|....:...:||....:.|||...|:.::.:|||.:.:|..
Mouse   472 KWMAAQMEPLRLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIGIHPLYVMIPCT 536

  Fly   487 LGISMVYFLPVSTPPNAIVTQYAHIK 512
            :..|:.:.|||:|||||||..|.|::
Mouse   537 MSASLAFMLPVATPPNAIVFAYGHLR 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Indy-2	NP_001027201.1	CitT	102..544	CDD:440239	142/442 (32%)
Slc13a5	XP_017170015.1	CitMHS	<48..200	CDD:460985	63/154 (41%)
		CitT	128..566	CDD:440239	142/442 (32%)