Protein Alignment Indy-2 and Slc13a2

DIOPT Version :10

• Sequence 1: NP_001027201.1
• Gene: Indy-2 / 3772456
• FlyBaseID: FBgn0260466
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_071856.1
• Gene: Slc13a2 / 20500
• MGIID: 1276558
• Length: 586
• Species: Mus musculus
• Alignment Length: 579
• Identity: 214/579 - (36%)
• Similarity: 315/579 - (54%)
• Gaps: 65/579 - (11%)

  Fly    20 WRGKASIII---P--LITLPILIYGFQTDMAEFKCLWLIVTMALLWITETLPIYVTALFPLVFCP 79
            |..::.:|:   |  |:.||:::   ||  .|..|.:.|:.|||||.||.||:.||||||::..|
Mouse     9 WAYRSYLIVLCLPIFLLPLPLIV---QT--KEAYCAYSIILMALLWCTEALPLAVTALFPIILFP 68

  Fly    80 LLGLVNASIVCKQYFTDTIVVFLGGLIVALGIEYSNLHTRIALRVIRIVGGSPRRLFVGLMSVST 144
            |:|::.||.||.:||.||.::|:|||:||:.:|:.|||.||||.|:.|:|..|..|.:|.|.|:.
Mouse    69 LMGIMEASKVCLEYFKDTNILFVGGLMVAIAVEHWNLHKRIALGVLLIIGVRPALLLLGFMLVTA 133

  Fly   145 FMGLWISNSAGTAMMCPIVKALVNEL-------DTNKIFPVYMTQEEEPVEE------------- 189
            |:.:||||:|.||||.||..|::.:|       :.....|.:..||..|.:|
Mouse   134 FLSMWISNTATTAMMLPIGYAVLEQLQGSQKDVEEGNSNPSFELQEASPQKEETKLDNGQAVSVS 198

  Fly   190 GEP-PHPSKITVAFYAG----IAYASSIGGLGTLIGTGTNLVFRGIYTERFPTSTVEITFANFMF 249
            .|| ...:|....|..|    |.|::||||:.||.||..|||.:|.....||.::..:.||::..
Mouse   199 SEPRAQKTKEHHRFSQGLSLCICYSASIGGIATLTGTTPNLVLQGQVNSIFPENSNVVNFASWFG 263

  Fly   250 YSIPLMVIVNVTLVIIAFL---ITHMGL-FRPNSKTGKIIAEANTNRKLME-DVLRQRHIDLGPM 309
            ::.|.|||    |:::|:|   :..:|: ||.|...|    |....||... .|::.:|..||||
Mouse   264 FAFPTMVI----LLLLAWLWLQVLFLGVNFRKNFGFG----EGEEERKQAAFQVIKTQHRLLGPM 320

  Fly   310 SCHEIQMAIAFAFMIVLLITRKPGFVPGWSD--LINRK---VVGSASGLSFIVLLIFALPTQYTF 369
            |..|..:...|..::||..||:|||.|||.|  ..|:|   :|...:...||.|::|.:|::..
Mouse   321 SFAEKAVTFLFVLLVVLWFTREPGFFPGWGDTAFANKKGQSMVSDGTVAIFISLIMFIIPSKIP- 384

  Fly   370 FKYCCG-----KGPFTAQAIDAILSWEYVLRNIPWGLLFLLGGGFALAVASRETGLNIMISKAMQ 429
                 |     |.|...:|..|||:|:.|...:||.:|.|||||||||..|.|:||:..:...:.
Mouse   385 -----GLTEDPKKPGKLKAPPAILTWKTVNDKMPWNILILLGGGFALAKGSEESGLSKWLGDKLT 444

  Fly   430 VLIGLPNIVVQSITFVLANFFSAFNANVVVANIVLPILCEMSLALELHPLILTLPACLGISMVYF 494
            .|..:|......|..:|...|:...:||....:.||||..|:.|:.||||.:.||..|..|:.:.
Mouse   445 PLQHVPPSATVLILSLLVAIFTECTSNVATTTLFLPILASMAQAICLHPLYVMLPCTLAASLAFM 509

  Fly   495 LPVSTPPNAIVTQYAHIKTKYFACCGIVPTIIGISVALVNTNTWGLIIFPESKSFPDWA 553
            |||:|||||||..:..:|....|..|.:..|||:....::.|:|.:.|| :..:||.||
Mouse   510 LPVATPPNAIVFSFGGLKVSDMARAGFLLNIIGVLTITLSINSWSIPIF-KLDTFPTWA 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Indy-2	NP_001027201.1	CitT	102..544	CDD:440239	171/481 (36%)
Slc13a2	NP_071856.1	ArsB_NhaD_permease	6..560	CDD:473875	210/570 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	165..209		8/43 (19%)