Protein Alignment Indy-2 and nac-2

DIOPT Version :9

• Sequence 1: NP_001027201.1
• Gene: Indy-2 / 3772456
• FlyBaseID: FBgn0260466
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001254976.1
• Gene: nac-2 / 187898
• WormBaseID: WBGene00003518
• Length: 585
• Species: Caenorhabditis elegans
• Alignment Length: 591
• Identity: 176/591 - (29%)
• Similarity: 292/591 - (49%)
• Gaps: 86/591 - (14%)

  Fly     3 EPGEQRKFVLGRCCIFHWRGKASIII--PLITLPILIYGFQTDMAEFKCLWLIVTMALLWITETL 65
            :|..||..:           |..:::  ||:.:|:|.:|     .|::||:.|:.::..||.|..
 Worm    36 KPSPQRTLI-----------KKLLVLLGPLVAVPLLFFG-----PEYRCLFSIIFLSTYWIGEAF 84

  Fly    66 PIYVTALFPLVFCPLLGLVNASIVCKQYFTDTIVVFLGGLIVALGIEYSNLHTRIALRVIRIVGG 130
            ||.||:||||...|:|.:|.:..:...||.|:||:|:..||:|:.:|.:.||.||||:::..||.
 Worm    85 PIGVTSLFPLALYPILQIVPSKQISPVYFKDSIVLFMCTLIMAMAVEATGLHRRIALKLLTKVGA 149

  Fly   131 SPRRLFVGLMSVSTFMGLWISNSAGTAMMCPIVKALVNELDTNKIFPVYMTQEEEPVEEGEPPHP 195
            ....:.:|.|.:::|:..::|::|.||:|||...||:..:..    .|...:|:.  .:.:|| |
 Worm   150 KQPVMLLGFMCITSFISFFVSDTACTALMCPTAVALLMSMSD----AVQHLKEDH--RKPKPP-P 207

  Fly   196 SKITV------------------AFYAGIAYASSIGGLGTLIGTGTNLVFRGIYTERFPTSTVEI 242
            ...||                  |.....|:||.|||...:..||.|||||....:|:|...|.:
 Worm   208 DDATVAEKLRIDDMTPQDAGFCKALILACAHASLIGGTAIITSTGPNLVFRENIHKRYPEGQVTM 272

  Fly   243 TFANFMFYSIPLMVIVNVT--LVIIAFLI---THMGLFRPNSKTGKIIAEANTNRKLMEDVLRQR 302
            |:..:|.::||.|.:..:.  ::::.:.:   |....|...||     .||:. :||:|..::..
 Worm   273 TYLQWMVFAIPPMFVYLLASYIILVCYFMGPSTFARWFERPSK-----EEAHL-KKLIEKNIQTM 331

  Fly   303 HIDLGPMSCHEIQMAIAFAFMIVLLITRKPGFVPGWSDLINRK--VVGSASGLSFIVLLIFALPT 365
            :.|||.:|..|..:.:.|..:|...|:|.|||.|||.||:..:  :..|.||: .|..::|..|
 Worm   332 YEDLGDVSWGEKSVFVFFILLIGSWISRDPGFTPGWGDLLPHRNFISDSVSGV-LISCILFVWP- 394

  Fly   366 QYTFFKYCCGKGPFTAQAID---AILSWEYVLRNIPWGLLFLLGGGFALAVASRETGLNIMISKA 427
                      |.||  ..||   .||.|..:.....|....|:|.|:|::....::||:.:||..
 Worm   395 ----------KDPF--DPIDPMAPILKWTDMKSKFSWSCTLLIGAGYAISEGVDKSGLSRLISCG 447

  Fly   428 MQ-VLIGLPNIVVQSITFVLANFFSAFNANVVVANIVLPILCEMSLALELHPLILTLPACLGISM 491
            |: :.:|:.::.:|.....:....:.|.:||...:|.:||...::.::.:|||.|.||..:..|.
 Worm   448 MKNIFVGMSSLPLQLTVTTIIVIMTEFASNVSTGSIFIPISLGVAESMGVHPLYLALPTTVACSF 512

  Fly   492 VYFLPVSTPPNAIVTQYAHIKTKYFACCGIVPTIIGISVALVNTNTW-----GLIIFP------- 544
            .:.||:||||||:|.....|.......||.:..|..|.:..:|.|||     .|.|||
 Worm   513 AFMLPISTPPNAVVYDTKVISMVEMIVCGFLLNIACILITSLNMNTWTYFIFSLNIFPENIVISS 577

  Fly   545 ESKSFP 550
            |:.|:|
 Worm   578 ENSSYP 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Indy-2	NP_001027201.1	ArsB_NhaD_permease	50..533	CDD:304373	154/511 (30%)
		dass	52..532	CDD:273267	153/508 (30%)
nac-2	NP_001254976.1	CitT	43..564	CDD:223547	166/563 (29%)
		ArsB_NhaD_permease	72..552	CDD:304373	153/506 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159147
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57284
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000298
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10283
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X273
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.950