Protein Alignment Indy-2 and nac-3

DIOPT Version :9

• Sequence 1: NP_001027201.1
• Gene: Indy-2 / 3772456
• FlyBaseID: FBgn0260466
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001022673.1
• Gene: nac-3 / 176429
• WormBaseID: WBGene00003519
• Length: 566
• Species: Caenorhabditis elegans
• Alignment Length: 547
• Identity: 158/547 - (28%)
• Similarity: 280/547 - (51%)
• Gaps: 55/547 - (10%)

  Fly    30 LITLPILIYG--FQTDMAEFKCLWLIVTMALLWITETLPIYVTALFPLVFCPLLGLVNASIVCKQ 92
            ::.|..|.:|  ...:..|:||.:.:..:|:.|::|.:|:.|||:.|:|..||:|:::|:...|:
 Worm    56 VLVLTPLFFGQMLNWEGPEWKCAYCVCIIAVYWMSEVMPLAVTAMLPVVLFPLVGVLDANTTAKE 120

  Fly    93 YFTDTIVVFLGGLIVALGIEYSNLHTRIALRVIRIVGGSPRRLFVGLMSVSTFMGLWISNSAGTA 157
            |..||..:|:||||:|..:|..:||.|:||.|:|.||..|:.:.:|.|:|:..:..:|||:|.||
 Worm   121 YMNDTNFLFIGGLIMAAAVEKCDLHERVALSVLRCVGSEPKWIMLGFMTVTALLSSFISNTATTA 185

  Fly   158 MMCPIVKALVNELDTNKIFPVYMTQEEEPVEEGEPPHPS----------KITVAFYAGIAYASSI 212
            ||.||.:::|.:|       :...|.          ||:          |:.......|.:|::|
 Worm   186 MMVPIGQSVVQQL-------ISSFQH----------HPTNGERGRLGCKKMATGLVLSICFAANI 233

  Fly   213 GGLGTLIGTGTNLVFRGIYTERFPTSTVEITFANFMFYSIPLMVIVNVTLVIIAFLITHMGLFRP 277
            ||.||..||.:|||..|..:..||.....:.:..::|::.|||::    .:.:|:: |.:..|
 Worm   234 GGTGTATGTPSNLVMLGQLSALFPKVDGSLNYVTWIFFAYPLMLL----CLFVAWM-TLVSFF-- 291

  Fly   278 NSKTGKIIAEANTNRKLMEDVLRQRHIDLGPMSCHEIQMAIAFAFMIVLLITRKPGFVPGWSDLI 342
                   :.:|....:.:.::|:.|:.:|..|:..|..:.:.|..::.|.:.|.||.|||:....
 Worm   292 -------LRDAPEKDEAVTEMLKTRYNELPRMTYAEKSVFVCFCILLSLWVFRNPGVVPGFGVFF 349

  Fly   343 NRKVVGSASGLSFIVLLIFALPTQ----YTFFKYCCGKGPFTAQAIDAILSWEYVLRNIPWGLLF 403
            .:.....|:....:..|:|.||::    .|:.|    |.....:.  .::.|:.:....||.::.
 Worm   350 KKGAYTDATSAMIVAFLLFVLPSERPDLATYIK----KEDLKKRG--CLMDWKTMQETFPWSVVL 408

  Fly   404 LLGGGFALAVASRETGLNIMISKAMQVLIGLPNIVVQSITFVLANFFSAFNANVVVANIVLPILC 468
            |||||||||...:|:||:::|..::..:..||..::|.:|.::|...:...:|.|.|:|.:||:.
 Worm   409 LLGGGFALAAGVKESGLSLLIGNSLSSIEHLPLWILQLLTMLIAMVITNICSNTVTASIFVPIVA 473

  Fly   469 EMSLALELHPLILTLPACLGISMVYFLPVSTPPNAIVTQYAHIKTKYFACCGIVPTIIGISVALV 533
            .::.....||..|.||..|..|..:..||.|||||||.....:|....|..|.:.::..:.:.::
 Worm   474 TLAQRAGHHPFTLMLPTTLASSFAFIFPVGTPPNAIVFGSGMVKVSDMAFVGGIISLELLVLTVL 538

  Fly   534 NTNTWGLIIFPESKSFPDWAKEIKNQT 560
            ..|:...:..| ...||.|| .|.|.|
 Worm   539 YMNSIAYLTLP-LLEFPTWA-IIANST 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Indy-2	NP_001027201.1	ArsB_NhaD_permease	50..533	CDD:304373	143/496 (29%)
		dass	52..532	CDD:273267	143/493 (29%)
nac-3	NP_001022673.1	SLC13_permease	83..543	CDD:238535	144/496 (29%)
		dass	84..539	CDD:273267	143/491 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	316	1.000	Domainoid score	I685
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	329	1.000	Inparanoid score	I1442
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57284
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000298
OrthoInspector	1	1.000	-	-		mtm4842
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10283
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X273
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.070