Protein Alignment Indy-2 and B0285.6

DIOPT Version :9

• Sequence 1: NP_001027201.1
• Gene: Indy-2 / 3772456
• FlyBaseID: FBgn0260466
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001366690.1
• Gene: B0285.6 / 175563
• WormBaseID: WBGene00007138
• Length: 574
• Species: Caenorhabditis elegans
• Alignment Length: 573
• Identity: 183/573 - (31%)
• Similarity: 300/573 - (52%)
• Gaps: 64/573 - (11%)

  Fly    26 IIIPLITLPILIYGFQTDMAEFKCLWLIVTMALLWITETLPIYVTALFPLVFCPLLGLVNASIVC 90
            |:.|||..|:|.:|     .|.||.::|:||:..|:.|.:|:.||:..|::..|.||:|:...|.
 Worm    21 ILAPLILSPLLFFG-----QEGKCAFVILTMSCYWVAEVVPLAVTSFIPMIALPFLGIVSIKEVA 80

  Fly    91 KQYFTDTIVVFLGGLIVALGIEYSNLHTRIALRVIRIVGGSPRRLFVGLMSVSTFMGLWISNSAG 155
            .:||.||.:||...|:::|.:|...||.||||:::..||..|..|..|.|.:::|:.||||::|.
 Worm    81 PKYFADTNIVFFNSLMLSLAVEECQLHKRIALKMLTYVGTRPHWLMAGFMIITSFISLWISDTAC 145

  Fly   156 TAMMCPIVKALV--------------NELDTNKIFPVYMTQEEEPVE-EGEPPHPSKITV----- 200
            .|:|.||..||:              ||::..|||     .:|:|.| |.:....|:::|
 Worm   146 CALMAPIAYALLEEIMIPKMRPEEKENEIEVMKIF-----DKEDPEEKEKKKLDTSRLSVRDRGI 205

  Fly   201 --AFYAGIAYASSIGGLGTLIGTGTNLVFRGIYTERFPTSTVEITFANFMFYSIPLMVIVNVT-- 261
              .....:|:||.|||.||:..||.||:||....:.||.....|::.::|.::||.|:....:
 Worm   206 CKCMMLLVAHASLIGGTGTINSTGPNLIFRDNIEKNFPNEDHGISYLSWMAFAIPPMIFYMFSSW 270

  Fly   262 -LVIIAFLITH--MGLFRPNSKTGKIIAEANTNRKLMEDVLRQRHI-----DLGPMSCHEIQMAI 318
             :|.:.||...  ||:||..::|.|           .|:.:.:|.:     .||||:..|....:
 Worm   271 FIVQLQFLGPRHLMGMFREPTETEK-----------QEEEVAKRAVWKSYDQLGPMTWAEKSTLV 324

  Fly   319 AFAFMIVLLITRKPGFVPGWSDLINR-KVVGSASGLSFIVLLIFALPTQ---YTFFKYCCGKGPF 379
            .|...::..::..|..:||||||..: .|..|.||| ..|.|:|..|.:   :..|:....: |.
 Worm   325 IFVLAVLSWVSSDPKVIPGWSDLFRKGYVTDSCSGL-VAVFLLFIWPKKKPDFRIFRKDKSR-PS 387

  Fly   380 TAQAIDAILSWEYVLRNIPWGLLFLLGGGFALAVASRETGLNIMISKAMQVLIG-LPNIVVQSIT 443
            ..|  :.::.|:.|.|..||.::.|||.|||::.|.|.:||:.:|:.::...|. :|..|:|.|.
 Worm   388 VRQ--EPLIDWDCVRRRFPWSIILLLGAGFAISDAVRVSGLSSLIACSLNSTISKMPFFVMQIIL 450

  Fly   444 FVLANFFSAFNANVVVANIVLPILCEMSLALELHPLILTLPACLGISMVYFLPVSTPPNAIVTQY 508
            .::....:.|:.|...|:|.:||..:|:.|:..|||..::|..:|.|..:.||::||.||||.:.
 Worm   451 SIVVVVMTEFSTNSATASIFIPISFKMAEAVGAHPLYFSIPTAIGPSFSFMLPMATPANAIVYET 515

  Fly   509 AHIKTKYFACCGIVPTIIGISVALVNTNTWGLIIFPESKSFPDWA-KEIKNQT 560
            ..|:......||:...|..|::..:|.|||...:| ...::||:| :...|.|
 Worm   516 KTIRMIDMVSCGVFLNIFCIAITAINMNTWAFWLF-NMGTYPDYALRHATNMT 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Indy-2	NP_001027201.1	ArsB_NhaD_permease	50..533	CDD:304373	163/519 (31%)
		dass	52..532	CDD:273267	163/516 (32%)
B0285.6	NP_001366690.1	ArsB_NhaD_permease	42..540	CDD:419678	163/517 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159148
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0471
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57284
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000298
OrthoInspector	1	1.000	-	-		mtm4842
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10283
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X273
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.850