DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11891 and CG10514

DIOPT Version :9

Sequence 1:	NP_001027211.3	Gene:	CG11891 / 3772439	FlyBaseID:	FBgn0039309	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_651371.1	Gene:	CG10514 / 43052	FlyBaseID:	FBgn0039312	Length:	413	Species:	Drosophila melanogaster

Alignment Length:	408	Identity:	158/408 - (38%)
Similarity:	248/408 - (60%)	Gaps:	7/408 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PAWLTRDYVEQKLRSYFRNDSLRLVNLDIKLALGNGENYSSVITRIYVEYT-TDKSKDKQSTRFT 76
            |.|||.:|:|..||.:::::.|.:..|.|..|||.||||..|:||..||:| ::|.|:.|:....
  Fly     5 PEWLTHEYIEHALRCHYKDEGLTITQLQINPALGPGENYGGVLTRARVEFTLSNKEKNVQNLIVK 69

  Fly    77 RFADAGPAAQVLLS-YGVYNRELDLYERILPQMAEVVRNELADSRKLFAGTVYVDRKRDSIIFED 140
            ...|.....|.|:: |.:||||:.:|:.:||:..|:: ||:.|:.::|...:||||:|.:|||||
  Fly    70 TEIDDDELTQELMAPYDIYNREMTIYQEVLPKCRELL-NEIGDTERIFPTAIYVDRERMAIIFED 133

  Fly   141 MSLENYRVADRLKKLDLEHTHLVLEKLANFHAAGAALAERQPGIFAKNFDRGFFNQHTRGYEPIM 205
            :|:..|.:|||:::|:.|||||:|.|||.||||.|.|.|||.|.. :::||||||::|..|....
  Fly   134 LSVVGYVMADRVRRLNEEHTHLILRKLAKFHAATAVLNERQSGCL-ESYDRGFFNRYTNAYSGYF 197

  Fly   206 KNLLMALSRSLELEPDLCQRYQAKIDRLVENVMEYGERSTTIVPGDFLTLAHGDLWTTNIMFQYD 270
            ...|:|.:|.:...|.|. .|..|:..|..:.|:.|.......||....|||||:||.|:||:||
  Fly   198 VGGLLAAARWMSKVPTLA-HYGEKLFALAPHYMDIGRECFAPTPGQVNVLAHGDVWTNNVMFKYD 261

  Fly   271 -DKGHPINAIFIDFQFSAWNSPAIDLHYFFSTALQADIRLKKQPELVQFYYYKLNAALKKVQYSG 334
             :.|.|::.:.||||:|.|.||.||||:.|:|:|:..:|..:|..|.|||:......|:|:.|..
  Fly   262 PNTGRPVDVLLIDFQYSFWGSPCIDLHHLFNTSLKEPLRRDQQNGLFQFYHKIFTETLEKLNYRQ 326

  Fly   335 N-VPSLFVFHQQFRNRSFYAAFASLIFEPTMTYTGKEEASMDQIISLSEKGMRFKDDAFQAEETR 398
            | :|||..|..:...:.|:|..::::.:|.|......:|..:.:::..|:|:|||:..:.....:
  Fly   327 NQIPSLHQFKLEVEQKRFFALHSTVVVQPVMISQDPTDACFNALMNDDERGIRFKNRLYNNPTVQ 391

  Fly   399 KKMRLTLPFLDHLGLLDV 416
            :.:...:||.|..|||:|
  Fly   392 QNLHSLVPFFDRKGLLEV 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11891	NP_001027211.3	None
CG10514	NP_651371.1	EcKinase	39..324	CDD:281023	121/287 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	166	1.000	Domainoid score	I7989
eggNOG	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H115919
Inparanoid	1	1.050	53	1.000	Inparanoid score	I4082
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	7	7.060