DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11891 and CG6830

DIOPT Version :9

Sequence 1:	NP_001027211.3	Gene:	CG11891 / 3772439	FlyBaseID:	FBgn0039309	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_650103.1	Gene:	CG6830 / 41408	FlyBaseID:	FBgn0037934	Length:	891	Species:	Drosophila melanogaster

Alignment Length:	429	Identity:	111/429 - (25%)
Similarity:	204/429 - (47%)	Gaps:	27/429 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EINRSAQVVPAWLTRDYVEQKLRSYFRNDSLRLVNLDIKLALGNGENYSSVITRIYVEY-TTDKS 67
            |::.| .:||.||.:...|:.|.:.....| ::|...:|.|:..||||::::.||.::. .|||
  Fly    39 EVDHS-DLVPKWLNQTQFEELLAADVDQFS-KIVGFRVKPAMAPGENYATLMLRISIDVELTDK- 100

  Fly    68 KDKQSTRFTRFA-----DAGPAAQVLLSYGVYNRELDLYERILPQMAEVVRNELADSRKLFAGTV 127
                ||:...|.     |.....|::.....:..|...|..|||:|.|:.:.:..|.:  ||...
  Fly   101 ----STKLVSFMMKVPHDTPQMEQMMSMANFFTSENAAYTEILPKMEELYKAKGLDIK--FAPRA 159

  Fly   128 Y-VDRKRD-----SIIFEDMSLENYRVADRLKKLDLEHTHLVLEKLANFHAAGAALAERQPGIFA 186
            : :|..::     :::..|:....::..:||:.|:||.|...|.:||.||||||.:.:.. |.:.
  Fly   160 FKLDATKEPKVANTVLMHDLGQNGFKNINRLECLNLEQTKFALTRLAQFHAAGATMVQVH-GPYP 223

  Fly   187 KNFDRGFFNQHTRGYEPIMKNLLMALSRSLELEPDLC---QRYQAKIDRLVENV-MEYGERSTTI 247
            ..|..|....:.......|:.:|.:...|.....|..   :.|:.|:::.:..: ||: .:...:
  Fly   224 DIFVNGVMGNNKEAIIAFMEGMLASFRTSFMANLDKFKNGEEYREKLEKALAGLTMEF-MKLGIV 287

  Fly   248 VPGDFLTLAHGDLWTTNIMFQYDDKGHPINAIFIDFQFSAWNSPAIDLHYFFSTALQADIRLKKQ 312
            .|.:|..|.|||.|..|::|:.:..|...:.:|:|||...:.|||:||.||..:::|.|.:|...
  Fly   288 DPNEFNALNHGDCWMNNLLFKMNSSGDLEDMVFVDFQNPKYGSPAMDLLYFIISSVQIDYKLSHF 352

  Fly   313 PELVQFYYYKLNAALKKVQYSGNVPSLFVFHQQFRNRSFYAAFASLIFEPTMTYTGKEEASMDQI 377
            ...::.|...|...|..:.::|..|||...|:.......:..|.::...|.:.....:.|:.|..
  Fly   353 DFFIRHYQEALVKHLGILGFTGRKPSLRELHRTLIKYGGWVLFPTISVLPLVLLDPTQSATFDNF 417

  Fly   378 ISLSEKGMRFKDDAFQAEETRKKMRLTLPFLDHLGLLDV 416
            :|.|..|:.|:...:..:..::.:...||:||:.|.|:|
  Fly   418 MSDSADGVSFRGSLYANKRCQEYIERILPWLDNRGFLEV 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11891	NP_001027211.3	None
CG6830	NP_650103.1	EcKinase	80..372	CDD:281023	79/300 (26%)
CG6830	NP_650103.1	EcKinase	516..800	CDD:281023
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010