DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11891 and CG31380

DIOPT Version :9

Sequence 1:	NP_001027211.3	Gene:	CG11891 / 3772439	FlyBaseID:	FBgn0039309	Length:	417	Species:	Drosophila melanogaster
Sequence 2:	NP_733121.1	Gene:	CG31380 / 318701	FlyBaseID:	FBgn0051380	Length:	405	Species:	Drosophila melanogaster

Alignment Length:	409	Identity:	125/409 - (30%)
Similarity:	214/409 - (52%)	Gaps:	20/409 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 AWLTRDYVEQKLRSYFRNDSLRLVNLDIKLALGNGENYSSVITRIYVEYTTDKSKDKQSTRFTRF 78
            ||||.:|:|..||.|::|:.||:.::.|..|||.||||.:::|||::.|::...:...:.....:
  Fly     3 AWLTAEYLEAALRRYYQNNELRVESMVINPALGKGENYGAILTRIHLVYSSIVEEHLIAKTVLEY 67

  Fly    79 ADAGPAAQVLLSYGVYNRELDLYERILPQMAEVVRNELADSRKLFAGTVYVDRKRDSIIFEDMSL 143
            .|| ........|.:|||||::||::||::.|:...:|...      .:::||:|.::|.||:|.
  Fly    68 EDA-ETKMKKAPYDIYNRELEIYEQVLPKLQELAGEQLCPK------ILHIDRQRGALIMEDLSY 125

  Fly   144 ENYRVADRLKKLDLEHTHLVLEKLANFHAAGAALAERQPGIFAKNF-----DRGFFNQHTRGYEP 203
            :.:.:|.||::||.:|..|||.|||...||.|.|   :..:...||     |:||||::|..:..
  Fly   126 KGFVMAPRLQRLDEQHVSLVLRKLAKMQAASAVL---ENNLLENNFSLTEYDKGFFNRYTESFSA 187

  Fly   204 IMKNLLMALSRSLELEPDLCQRYQAK-IDRLVENVMEYGERSTTIVPGDFLTLAHGDLWTTNIMF 267
            .....|.:.:..|:.:..  ..:.|| :|.|....|..|.|...........|.||||||.|:||
  Fly   188 YFLGCLKSCANYLKTQAG--YEHHAKLLDELAPYYMGLGLRCFKQEQTHINVLTHGDLWTNNMMF 250

  Fly   268 QYDDKGHPINAIFIDFQFSAWNSPAIDLHYFFSTALQADIRLKKQPELVQFYYYKLNAALKKVQY 332
            :| :.|.|.:.:.||||::.|.||.:|:|:..:|:....:|.:.|.::...|:......|:::.:
  Fly   251 KY-EAGVPSDVLLIDFQYAFWGSPTLDIHHLLNTSAVEQVRSELQMKMRGVYHDVFVGELQRLGF 314

  Fly   333 SG-NVPSLFVFHQQFRNRSFYAAFASLIFEPTMTYTGKEEASMDQIISLSEKGMRFKDDAFQAEE 396
            .| .:||...||.:...:.|||....|:..|.:..|.:.:|....::|...:||..|...:....
  Fly   315 KGQRLPSRKQFHLESEQKRFYAVHCGLLLLPVLLNTDETDADFAALLSDQPRGMDMKRRLYLNPG 379

  Fly   397 TRKKMRLTLPFLDHLGLLD 415
            .:..::..:...:..||||
  Fly   380 IQDSIKQMVKHFELEGLLD 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11891	NP_001027211.3	None
CG31380	NP_733121.1	EcKinase	36..314	CDD:281023	89/290 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	166	1.000	Domainoid score	I7989
eggNOG	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H115919
Inparanoid	1	1.050	53	1.000	Inparanoid score	I4082
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X109
	7	7.060