Protein Alignment Adhr and HPGD

DIOPT Version :10

• Sequence 1: NP_477495.1
• Gene: Adhr / 3772432
• FlyBaseID: FBgn0000056
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_000851.2
• Gene: HPGD / 3248
• HGNCID: 5154
• Length: 266
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 66/248 - (26%)
• Similarity: 116/248 - (46%)
• Gaps: 23/248 - (9%)

  Fly     4 LTGKHVCYVADCGGIALETSKVLMTKNIAKLAILQSTENPQAIAQL-----QSIKPSTQIFFWTY 63
            :.||.........||....::.|:.|. ||:|::.  .|.:|..|.     :..:|...:|. ..
Human     3 VNGKVALVTGAAQGIGRAFAEALLLKG-AKVALVD--WNLEAGVQCKAALDEQFEPQKTLFI-QC 63

  Fly    64 DVTMAREDMKKYFDEVMVQMDYIDVLINGATLCDENNIDATINTNLTGMMNTVATVLPYMDRKMG 128
            ||. .::.::..|.:|:.....:|:|:|.|.:.:|.|.:.|:..||..:::.....|.||.::.|
Human    64 DVA-DQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNG 127

  Fly   129 GTGGLIVNVTSVIGLDP---SPVFCAYSASKFGVIGFTRSLADPLYYSQNGVAVMAVCCGPTRVF 190
            |.||:|:|::|:.||.|   .||:|   |||.|::|||||.|.......:||.:.|:|.|.....
Human   128 GEGGIIINMSSLAGLMPVAQQPVYC---ASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTA 189

  Fly   191 V------DRELKAFLEYGQSFADRLRRAPCQSTSVCGQNIVNAIERSE-NGQI 236
            :      :..:..::||.....|.::........:....::..||... ||.|
Human   190 ILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNGAI 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adhr	NP_477495.1	ADH_SDR_c_like	7..248	CDD:187584	65/245 (27%)
HPGD	NP_000851.2	ADH_SDR_c_like	6..254	CDD:187584	65/245 (27%)