DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33673 and TMBIM4

DIOPT Version :9

Sequence 1:	NP_001027218.2	Gene:	CG33673 / 3772423	FlyBaseID:	FBgn0053673	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_001269535.1	Gene:	TMBIM4 / 51643	HGNCID:	24257	Length:	285	Species:	Homo sapiens

Alignment Length:	223	Identity:	57/223 - (25%)
Similarity:	103/223 - (46%)	Gaps:	23/223 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 YSRRIFISRVLMIVAINLLVTTLIMTFCVFHMGARKF------LLKHWYIGLVGMGIILIFSFMI 78
            |....|:.:|..|:::.:|:||:..|..::....|.|      |:..:.:|.:|    |||:.::
Human    76 YKGPTFLRKVYSILSLQVLLTTVTSTVFLYFESVRTFVHESPALILLFALGSLG----LIFALIL 136

  Fly    79 CCCSFLFRSSPCKYILLVIYVLAHSTVVCSAAVRYQPKLVFIAVASCAAIVVMLCLFARFAPCDF 143
            ....:     |....||..:.|..:..|......|...::..|......:...|.::...:..||
Human   137 NRHKY-----PLNLYLLFGFTLLEALTVAVVVTFYDVYIILQAFILTTTVFFGLTVYTLQSKKDF 196

  Fly   144 TGCWIFVFVLSLVVLIMGIVAIFF--PTIRIVYASLGVLLFCVYIVIDVQMIIGGGTHKNEFDES 206
            :.....:|.|..::.:.|.:..||  ..:.:|.|:.|.||||.:|:.|...::    ||  ....
Human   197 SKFGAGLFALLWILCLSGFLKFFFYSEIMELVLAAAGALLFCGFIIYDTHSLM----HK--LSPE 255

  Fly   207 DYVLAAMSLYSDIVFLFLYLLDLIGLID 234
            :|||||:|||.||:.|||:||..:..::
Human   256 EYVLAAISLYLDIINLFLHLLRFLEAVN 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33673	NP_001027218.2	LFG_like	16..231	CDD:198410	57/218 (26%)
TMBIM4	NP_001269535.1	GAAP_like	6..283	CDD:198411	57/221 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0670
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57711
OrthoDB	1	1.010	-	-		D1290306at2759
OrthoFinder	1	1.000	-	-		FOG0000200
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2042
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.830