DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33673 and tmbim4

DIOPT Version :9

Sequence 1:	NP_001027218.2	Gene:	CG33673 / 3772423	FlyBaseID:	FBgn0053673	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_998303.2	Gene:	tmbim4 / 406412	ZFINID:	ZDB-GENE-040426-2152	Length:	236	Species:	Danio rerio

Alignment Length:	222	Identity:	57/222 - (25%)
Similarity:	102/222 - (45%)	Gaps:	33/222 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 RRIFISRVLMIVAINLLVTTLIMTFCVFHMGARKFLLKH---WYIGLVGMGIILIFSFMICCCSF 83
            |..|:.:|..|:::.:::||.:....:.....:.|:.:.   ..|..:|..|:|:      ..:|
Zfish    29 RMDFLRKVYTILSLQIIITTAVSALFMLCNPIKNFVHESPSLVLISAIGSLILLL------ALAF 87

  Fly    84 LFRSSPCKYILLVIYVLAHSTVVCSAAVRYQPKLVFIAVASCAAIVVMLCL--------FARFAP 140
            .....|....||..:.|..|..|.:|...|:..:|..|....:|:.:.|..        |::...
Zfish    88 YRHQHPVNLYLLFGFTLLESLSVATAVSFYEYTIVLQAFVLTSAVFLGLTAYTFQSKRDFSKLGA 152

  Fly   141 CDFTGCWIFVFVLSLVVLIMGIVAIFF--PTIRIVYASLGVLLFCVYIVIDVQMIIGGGTHKNEF 203
            ..|.|.||        ::|...:..||  .|:.:|:|..|.||||.:|:.|..:::    ||  .
Zfish   153 SLFAGLWI--------LIIASFLRFFFYNDTMELVFAGAGALLFCGFIIFDTHLLM----HK--L 203

  Fly   204 DESDYVLAAMSLYSDIVFLFLYLLDLI 230
            ...::|||:::||.|||.||||:|.::
Zfish   204 SPEEHVLASINLYLDIVNLFLYILRIL 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33673	NP_001027218.2	LFG_like	16..231	CDD:198410	57/222 (26%)
tmbim4	NP_998303.2	GAAP_like	4..233	CDD:198411	57/222 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0670
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57711
OrthoDB	1	1.010	-	-		D1290306at2759
OrthoFinder	1	1.000	-	-		FOG0000200
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2042
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830