DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33673 and Tmbim4

DIOPT Version :9

Sequence 1:	NP_001027218.2	Gene:	CG33673 / 3772423	FlyBaseID:	FBgn0053673	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_954547.1	Gene:	Tmbim4 / 362884	RGDID:	735173	Length:	238	Species:	Rattus norvegicus

Alignment Length:	250	Identity:	66/250 - (26%)
Similarity:	115/250 - (46%)	Gaps:	41/250 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 EREPMY----FEDRYS------------RRIFISRVLMIVAINLLVTTLIMTFCVFHMGARKF-- 56
            :.:|.|    .||.::            |..|:.:|..|:::.:|:||:.....::....|.|
  Rat     3 DTDPRYPRSSIEDDFNYGSCVASASVHIRMAFLRKVYSILSLQVLLTTVTSALFLYFETLRTFVH 67

  Fly    57 ----LLKHWYIGLVGMGIILIFSFMICCCSFLFR-SSPCKYILLVIYVLAHSTVVCSAAVRYQPK 116
                |:..:.:|.:|    |||:..      |.| :.|....||..:.|:.:..|.:....|...
  Rat    68 DSPALIVVFALGSLG----LIFALT------LHRHTHPLNLYLLFAFTLSEALTVATVVTFYDGH 122

  Fly   117 LVFIAVASCAAIVVMLCLFARFAPCDFTGCWIFVFVLSLVVLIMGIVAIFF--PTIRIVYASLGV 179
            ||..|....||:.:.|..:...:..||:.....:|....::.:.|.:.:||  .|:.:|.||||.
  Rat   123 LVLHAFILTAAVFLGLTAYTLQSKRDFSKFGAGLFACLWILCLAGFLKVFFYSQTVELVLASLGA 187

  Fly   180 LLFCVYIVIDVQMIIGGGTHKNEFDESDYVLAAMSLYSDIVFLFLYLLDLIGLID 234
            ||||.:|:.|...::      :.....:|||||:|||.||:.|||:||..:..::
  Rat   188 LLFCGFIIYDTHSLM------HRLSPEEYVLAAISLYLDIINLFLHLLKFLDAVN 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33673	NP_001027218.2	LFG_like	16..231	CDD:198410	64/235 (27%)
Tmbim4	NP_954547.1	GAAP_like	6..236	CDD:198411	66/245 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0670
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57711
OrthoDB	1	1.010	-	-		D1290306at2759
OrthoFinder	1	1.000	-	-		FOG0000200
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2042
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.830