DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33673 and FAIM2

DIOPT Version :9

Sequence 1:	NP_001027218.2	Gene:	CG33673 / 3772423	FlyBaseID:	FBgn0053673	Length:	235	Species:	Drosophila melanogaster
Sequence 2:	NP_036438.2	Gene:	FAIM2 / 23017	HGNCID:	17067	Length:	316	Species:	Homo sapiens

Alignment Length:	228	Identity:	61/228 - (26%)
Similarity:	110/228 - (48%)	Gaps:	20/228 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 FEDRYSRRIFISRVLMIVAINLLVTTLIMTFCVFHMGARKFLLKH--WYIGLVGMGIILIFSFMI 78
            ::|:..||:|:.:|..|:.|.||||..::....|....:.::..:  ||  .....:.......:
Human    93 WDDQKVRRVFVRKVYTILLIQLLVTLAVVALFTFCDPVKDYVQANPGWY--WASYAVFFATYLTL 155

  Fly    79 CCCSFLFRSSPCKYILLVIYVLAHSTVVCSAAVRYQPKLVFIAVASCAAIVVMLCL----FARFA 139
            .|||...|..|...|||.::.|:.:.:....:..|....|.:    |..|..::||    |:...
Human   156 ACCSGPRRHFPWNLILLTVFTLSMAYLTGMLSSYYNTTSVLL----CLGITALVCLSVTVFSFQT 216

  Fly   140 PCDFTGCWIFVFVLSLVVLIMG-IVAI-----FFPTIRIVYASLGVLLFCVYIVIDVQMIIGGGT 198
            ..|||.|...:|||.:.:...| |:||     :.|.:..|||:||..:|.:::.:|.|:::|...
Human   217 KFDFTSCQGVLFVLLMTLFFSGLILAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGNRR 281

  Fly   199 HKNEFDESDYVLAAMSLYSDIVFLFLYLLDLIG 231
            |  .....:|:..|:::|.||:::|.:.|.|.|
Human   282 H--SLSPEEYIFGALNIYLDIIYIFTFFLQLFG 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33673	NP_001027218.2	LFG_like	16..231	CDD:198410	60/226 (27%)
FAIM2	NP_036438.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..53
FAIM2	NP_036438.2	LFG_like	92..312	CDD:198410	60/226 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0670
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57711
OrthoDB	1	1.010	-	-		D1290306at2759
OrthoFinder	1	1.000	-	-		FOG0000200
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.830