Protein Alignment CG4970 and CFAP184

DIOPT Version :10

• Sequence 1: NP_001027253.1
• Gene: CG4970 / 3772412
• FlyBaseID: FBgn0032364
• Length: 690
• Species: Drosophila melanogaster
• Sequence 2: NP_699207.1
• Gene: CFAP184 / 257236
• HGNCID: 26900
• Length: 555
• Species: Homo sapiens
• Alignment Length: 564
• Identity: 103/564 - (18%)
• Similarity: 197/564 - (34%)
• Gaps: 198/564 - (35%)

  Fly   206 PDWDELSDIGTTDHNLGIDKKSVEMQQVPGSELEQLQIQLARKSLSSSME------------SLI 258
            |:.:|.:::|..:          ..|..||:..|:|:.:...:.|..:.|            :.|
Human    95 PEPEEPAEVGAEE----------PAQPEPGAGPEELEAEAGAEELEQAAEGKEVRFQASLPLTRI 149

  Fly   259 PSESNYEAPSSQ------NDDDVHGTE-------------IPSPS--------GLESVDESDW-- 294
            ..|....||.::      .::|...|:             .|:.|        |.:..::.:|
Human   150 DEEEAAAAPEAETERVEGEEEDKEETQRDGAESKERDGEGRPAKSQEEGKRLYGRDEFEDLEWSE 214

  Fly   295 ---RLQGMQFKSSHVATFKDITSESRSSTSSLNSIPTTFSIGQMVQSYLDGLIEKVVDIFVNTDY 356
               :||..|.:|..:..::.:..|...|              |....||...|.:.:
Human   215 EVQKLQEQQLRSDLLDQYRSLLVERNRS--------------QRYNLYLQHKIFEAL-------- 257

  Fly   357 LRSKNLDKSKLMNRLFKEVEDHHWVSHDNNLLTKRLTEHHLRRFKYSLVTPSSRSYINESQRSRY 421
            .|.|.|:.:::.:| ..|.|                            .....::|:      |:
Human   258 RRKKGLEAAEVADR-GAEAE----------------------------APEKEQAYL------RH 287

  Fly   422 LGALNELDHWLNRTRQAEQMHLAEKERLLSELERMQREDNEKIERLEEIFR------STLLRDSQ 480
            ||.|.||     :.:||:.:....:     ||.:::|:..||:.|:|:.:|      ..::..:.
Human   288 LGMLEEL-----KKQQADDLQWYHQ-----ELGQLKRQCQEKLTRVEKEWRRFQALKKQVVMQAM 342

  Fly   481 PSERLRFVTETALKQMR-------AKRDALSATRLILIIRQHDNSYIKKKVDEIEAISGEVKLET 538
            .|.|:|...:.||:::.       .|...:||.||       :|..:|:.:         |..||
Human   343 GSCRMRGGRQAALREVEQIQALEDKKEKEMSAVRL-------ENIQLKQSL---------VHFET 391

  Fly   539 YLSADNDVQQMV------------TTLNNK----NAELERMCTLVKTKIHTISHLRCRRKLLNRK 587
            .:....|:.|.:            .|.|.|    |.||.::.:.|...:..|:|::.:...::.:
Human   392 RMRTQEDLTQGLLLIDFEQLKIENQTFNEKIEERNEELLKLRSKVTNSVQVITHVKEKLHFMDME 456

  Fly   588 FREAKDELRERQKRQIALRDEVYNCNLTHNKLLDQIKEVRREG------------GIMCYPKLLA 640
            ....|.:|.|.:.:....||           :|.:.|:. |||            |::....||.
Human   457 NACKKTQLAEIEAQAALGRD-----------ILTKTKQA-REGLRTDNIRLNQKCGLLGKDSLLR 509

  Fly   641 DF----DRTEKFIAIKQASIVELKTQHDNLLKRIEKIELKILES 680
            |.    |:||    :....:..||..|.:|......:..||.|:
Human   510 DLEEKVDKTE----LLHRRLESLKRHHASLTLSCRGVRQKIREA 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4970	NP_001027253.1	DUF4201	496..672	CDD:464008	42/214 (20%)
CFAP184	NP_699207.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..202		18/116 (16%)
		DUF4201	365..541	CDD:464008	42/207 (20%)