DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp9f3 and Cyp6a19

DIOPT Version :9

Sequence 1:	NP_001350862.1	Gene:	Cyp9f3 / 3772405	FlyBaseID:	FBgn0038034	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_611001.2	Gene:	Cyp6a19 / 36662	FlyBaseID:	FBgn0033979	Length:	503	Species:	Drosophila melanogaster

Alignment Length:	379	Identity:	110/379 - (29%)
Similarity:	188/379 - (49%)	Gaps:	50/379 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 WASANNDFFKDRGIAYEKPVLYLGN---------MAGMFLRKRAMLDIVCDLYTKGGSGKFFGIF 74
            |...|..::|.|||.::.|.:.|||         :||:.  ||..|.     :.|...|.|.|.:
  Fly    18 WVLQNYTYWKRRGIPHDPPNIPLGNTGELWRTMPLAGIL--KRTYLK-----FRKQTDGPFAGFY 75

  Fly    75 AQRQPLLMVRDPDLIKQITIKDFDHFINHRNEFDTSSDDDPHDMSNLFSSSLFSMRDARWKDMRS 139
            ......:::.|.|.:|.:.|:|||.|  |......:..|||      .:::|.::...:||::|.
  Fly    76 LYAMKYIVITDVDFVKTVLIRDFDKF--HDRGVYHNEKDDP------LTNNLATIEGQKWKNLRQ 132

  Fly   140 TLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQENE--LDMKDYCTRFTNDVIASTAFGLQ 202
            .|:..||.:||:.||..:..|..|.:..:   |.::..:.  |::.|..:|||:|||...||||:
  Fly   133 KLTHTFTSAKMKSMFSTVLNVGDEMIRVV---DEKISSSSQTLEVTDIVSRFTSDVIGICAFGLK 194

  Fly   203 VNSFKDRENTFYQMGKKLTTFTFLQNMKF-----ILLFALKSLNKILKVEIFDRKSTQYFVRLVL 262
            .||.:|.:..|.|||     ::.|:..:.     :|:|.:..|...|..:.......::::::|.
  Fly   195 CNSLRDPKAEFVQMG-----YSALRERRHGWLVDLLIFGMPKLAVKLGFQFLLPSVQKFYMKIVQ 254

  Fly   263 DAMKYRQEHNIVRPDMINMLMEARGIIQTEKTKASAVREWSDRDIVAQCFVFFFAGFETSAVLMC 327
            |.:.||.:..:.|.|.::.|::    ::.:..|.......:..::.||.||||.||||..:..|.
  Fly   255 DTIDYRMKRKVTRNDFMDTLID----MKQQYDKGDKENGLAFNEVAAQAFVFFLAGFEAGSTTMG 315

  Fly   328 FTAHELMENQDVQQRLYEEVQQVDQDLEGK-------ELKYLDQVVSEVLRKWP 374
            ||.:||..|||||.:|..|:..|.:...||       :|.|:::|::|.|||.|
  Fly   316 FTLYELACNQDVQDKLRAEIDSVLERYNGKLEYDSMQDLFYMEKVINESLRKHP 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp9f3	NP_001350862.1	p450	36..>388	CDD:325183	104/362 (29%)
Cyp6a19	NP_611001.2	p450	32..495	CDD:278495	104/365 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461250
Domainoid	1	1.000	171	1.000	Domainoid score	I2249
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2893
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	9	8.900