Protein Alignment bw and PDR18

DIOPT Version :9

• Sequence 1: NP_001286769.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_014468.3
• Gene: PDR18 / 855807
• SGDID: S000005353
• Length: 1333
• Species: Saccharomyces cerevisiae
• Alignment Length: 689
• Identity: 148/689 - (21%)
• Similarity: 262/689 - (38%)
• Gaps: 210/689 - (30%)

  Fly    19 WKQLNYYVPDQEQSNYSFWNECRKKRELRILQDASGHMKTGDLIAILGGSGAGKTTLLAAISQRL 83
            ||.:::.:|             ....:.::|...||:...|.|.|::|.|||||||||..::||.
Yeast   731 WKNVSFTIP-------------HSSGQRKLLDSVSGYCVPGTLTALIGESGAGKTTLLNTLAQRN 782

  Fly    84 RGNLTGDVVLNGMAMERHQMTRISSFLPQFEINVKTFTAYEHLYFMSHFKMHRRTTKAEKRQRVA 148
            .|.:|||::::|:.|:. ...|.:.::.|.:::|...|..|.|.|.:..:..:....|||.:.|.
Yeast   783 VGTITGDMLVDGLPMDA-SFKRRTGYVQQQDLHVAELTVKESLQFSARMRRPQSIPDAEKMEYVE 846

  Fly   149 DLLLAVGLRDAAHTRIQQLSGG----ERKRLSLAEELITDP-IFLFCDEPTTGLDSFSAYSVIKT 208
            .::..:.:::.:...:.::..|    :||:||:..||:..| :.||.||||:||||.||::|:|.
Yeast   847 KIISILEMQEFSEALVGEIGYGLNVEQRKKLSIGVELVGKPDLLLFLDEPTSGLDSQSAWAVVKM 911

  Fly   209 LRHLCTRRRIAKHSLNQVYGEDSFETPSGESSASGSGSKSIEMEVVAESHESLLQTMRELPALGV 273
            |:.|..                     :|:|
Yeast   912 LKRLAL---------------------AGQS---------------------------------- 921

  Fly   274 LSNSPNGTHKKAAICSIHQPTSDIFELFTHIILM-DGGRIVYQG----RTEQAAKFFTDLG-YEL 332
                        .:|:||||::.:||.|..::|: .||:.:|.|    .:....|:|...| .:.
Yeast   922 ------------ILCTIHQPSATLFEQFDRLLLLGKGGQTIYFGEIGKNSSSVIKYFEKNGARKC 974

  Fly   333 PLNCNPADFYLKTLADKEGKENAGAVLRAKYEHETDGLYSGSWLLARSYS------GDYLKHVQN 391
            ..|.|||::.|:.:       .|||....:..      :...|..:..|:      .|.:|.:.:
Yeast   975 QQNENPAEYILEAI-------GAGATASVQQN------WPDIWQKSHEYANINEKINDMIKDLSS 1026

  Fly   392 FK-----------KIRWIYQVYLLMVRFMTEDLRNIRSGLIAFGFFMITAVTLSLMYSGIGGLTQ 445
            ..           ...:.||.:.::.|......||:.         .|.|..:.||.||:  ...
Yeast  1027 TTLHKTATRASKYATSYSYQFHHVLKRSSLTFWRNLN---------YIMAKMMLLMISGL--FIG 1080

  Fly   446 RTVQDVGGSIFMLSNEMIFTFSYGVTYIFPAALPIIRR--------EVGEGTYSLSAYYVALV-- 500
            .|...||.:...|.|.:...| ..:....||...|..|        ||.|...::..:.:.|:
Yeast  1081 FTFFHVGVNAIGLQNSLFACF-MAIVISAPATNQIQERATVAKELYEVRESKSNMFHWSLLLITH 1144

  Fly   501 -LSFVPVAFFKGYVFLSVIYASIYY--------TRGFLLYLSMGFLMSLSAVAAVGYGVFLSSLF 556
             |:.:|...    :|.::.:.|.|:        :|..:.||:...|..|..:     |:.|..|:
Yeast  1145 YLNELPYHL----LFSTIFFVSSYFPLGVFTEASRSSVFYLNYAILFQLYYI-----GLALMILY 1200

  Fly   557 ESDKMAS-ECAAPFDLIFLI-FGGTYMNVDTVPGLKYLSLFFYSNEALMYKFWIDIDNIDCPVNE 619
            .|..:.| .....|.|.||: |.|.......:||                 ||..:
Yeast  1201 MSPNLQSANVIVGFILSFLLSFCGAVQPASLMPG-----------------FWTFM--------- 1239

  Fly   620 DHPCIKTGVEVLQQGSYRNADYTYWLDCFSLVVVAVIFH 658
                            ::.:.|||:|.    .:|.::.|
Yeast  1240 ----------------WKLSPYTYFLQ----NLVGLLMH 1258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	73/290 (25%)
		3a01204	40..673	CDD:273361	145/668 (22%)
		ABC2_membrane	404..604	CDD:279410	46/220 (21%)
PDR18	NP_014468.3	3a01205	1..1333	CDD:273362	148/689 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	1	0.960