DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bw and ABCG19

DIOPT Version :9

Sequence 1:	NP_001286769.1	Gene:	bw / 37724	FlyBaseID:	FBgn0000241	Length:	675	Species:	Drosophila melanogaster
Sequence 2:	NP_191073.1	Gene:	ABCG19 / 824679	AraportID:	AT3G55130	Length:	725	Species:	Arabidopsis thaliana

Alignment Length:	767	Identity:	178/767 - (23%)
Similarity:	305/767 - (39%)	Gaps:	207/767 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GSSGQGGPS-------------------LCLEWKQLNYYVPDQEQSNYSFWNECRKKRELRILQD 51
            |.||.|..|                   ..|.:..|.|.|..:.:..:|     |:.....:|.|
plant    43 GDSGDGVKSDDPAHHIIDVEALYVKPVPYVLNFNNLQYDVTLRRRFGFS-----RQNGVKTLLDD 102

  Fly    52 ASGHMKTGDLIAILGGSGAGKTTLLAAISQRL-RGNLTGDVVLNGMAMERHQMTR-ISSFLPQFE 114
            .||....||::|:||.|||||:||:.|::.|: .|:|.|.|.|||..:.:.::.: ||:::.|.:
plant   103 VSGEASDGDILAVLGASGAGKSTLIDALAGRVAEGSLRGSVTLNGEKVLQSRLLKVISAYVMQDD 167

  Fly   115 INVKTFTAYEHLYFMSHFKMHRRTTKAEKRQRVADLLLAVGLRDAAHTRI-----QQLSGGERKR 174
            :.....|..|.|.|.|.|::.|..:|::|.:||..|:..:|||:||:|.|     :.:|||||:|
plant   168 LLFPMLTVKETLMFASEFRLPRSLSKSKKMERVEALIDQLGLRNAANTVIGDEGHRGVSGGERRR 232

  Fly   175 LSLAEELITDPIFLFCDEPTTGLDSFSAYSVIKTLRHLCTRRRIAKHSLNQVYGEDSFETPSGES 239
            :|:..::|.|||.||.||||:||||.:|:.|::.|      :|||:
plant   233 VSIGIDIIHDPIVLFLDEPTSGLDSTNAFMVVQVL------KRIAQ------------------- 272

  Fly   240 SASGSGSKSIEMEVVAESHESLLQTMRELPALGVLSNSPNGTHKKAAICSIHQPTSDIFELFTHI 304
                |||                                      ..|.|||||::.|.||...:
plant   273 ----SGS--------------------------------------IVIMSIHQPSARIVELLDRL 295

  Fly   305 ILMDGGRIVYQGRTEQAAKFFTDLGYELPLNCNPADFYLKTLADKEGKENAGAVL---RAKYEH- 365
            |::..|:.|:.|.......||:|.|..:|...|.::|.|..:.:.||.......|   ..|::.
plant   296 IILSRGKSVFNGSPASLPGFFSDFGRPIPEKENISEFALDLVRELEGSNEGTKALVDFNEKWQQN 360

  Fly   366 ---------ETDGL-----------YSGSWLLARSYSGDYLKHVQNFKKIR-----WIYQVYLLM 405
                     :|:.|           .:.|....:..||....:..:.:.:.     .:::.::|.
plant   361 KISLIQSAPQTNKLDQDRSLSLKEAINASVSRGKLVSGSSRSNPTSMETVSSYANPSLFETFILA 425

  Fly   406 VRFMTEDLRNIRSGLIAFGFFMITAVTLSLMYSGIGGLTQRTVQDVGGSIFMLSNEMIFTFSYGV 470
            .|:|...:|............|:|...|:.:|..:.. |.|..|           |.:..|::.|
plant   426 KRYMKNWIRMPELVGTRIATVMVTGCLLATVYWKLDH-TPRGAQ-----------ERLTLFAFVV 478

  Fly   471 TYIFPAALP----------IIRREVGEGTYSLSAYYVALVLSFVPVAFFKGYVFLSVIYASIYYT 525
            ..:|...|.          |..||.....|..|:|.::..|..:|.......||.::.:.::..:
plant   479 PTMFYCCLDNVPVFIQERYIFLRETTHNAYRTSSYVISHSLVSLPQLLAPSLVFSAITFWTVGLS 543

  Fly   526 ---RGFLLYLSMGFLMSLSAVAAVGYGVFLSSLFESDKMASECAAPFDLIFLIFGGTYMNVDTVP 587
               .||:.|..:.:....|..:.|   .|:|.:..:..:....:..:....|:..|.|:|.|.:|
plant   544 GGLEGFVFYCLLIYASFWSGSSVV---TFISGVVPNIMLCYMVSITYLAYCLLLSGFYVNRDRIP 605

  Fly   588 ----GLKYLSLFFYSNEALMYKFWIDIDNIDCP------------------VNE----------- 619
                ...|:|:..|..||::      |:..|.|                  |::
plant   606 FYWTWFHYISILKYPYEAVL------INEFDDPSRCFVRGVQVFDSTLLGGVSDSGKVKLLETLS 664

  Fly   620 --------DHPCIKTGVEVL-QQGSYRNADYTYWLDCFSLVVVAVIFHIVSF 662
                    :..|::||.::| |||.   ...:.| ||..:...:.:|..:.|
plant   665 KSLRTKITESTCLRTGSDLLAQQGI---TQLSKW-DCLWITFASGLFFRILF 712

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	91/291 (31%)
		3a01204	40..673	CDD:273361	168/714 (24%)
		ABC2_membrane	404..604	CDD:279410	44/216 (20%)
ABCG19	NP_191073.1	P-loop_NTPase	89..307	CDD:304359	91/289 (31%)
		3a01204	90..724	CDD:273361	169/720 (23%)
		ABC2_membrane	424..627	CDD:279410	44/223 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.880