DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bw and ABCG16

DIOPT Version :9

Sequence 1:	NP_001286769.1	Gene:	bw / 37724	FlyBaseID:	FBgn0000241	Length:	675	Species:	Drosophila melanogaster
Sequence 2:	NP_191069.2	Gene:	ABCG16 / 824675	AraportID:	AT3G55090	Length:	736	Species:	Arabidopsis thaliana

Alignment Length:	777	Identity:	188/777 - (24%)
Similarity:	291/777 - (37%)	Gaps:	251/777 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LEWKQLNYYVPDQEQSNYSF---WNECRKKRELRILQDASGHMKTGDLIAILGGSGAGKTTLLAA 78
            |.:..|.|.|..:.:.::..   |......:...:|.:.||..:.|:::|:||.||:||:||:.|
plant    73 LSFNNLTYNVSVRRKLDFHDLVPWRRTSFSKTKTLLDNISGETRDGEILAVLGASGSGKSTLIDA 137

  Fly    79 ISQRL-RGNLTGDVVLNGMAMERHQMTRISSFLPQFEINVKTFTAYEHLYFMSHFKMHRRTTKAE 142
            ::.|: :|:|.|.|.|||.|::...:..||:::.|.::.....|..|.|.|.:.|::.|...|::
plant   138 LANRIAKGSLKGTVTLNGEALQSRMLKVISAYVMQDDLLFPMLTVEETLMFAAEFRLPRSLPKSK 202

  Fly   143 KRQRVADLLLAVGLRDAAHTRI-----QQLSGGERKRLSLAEELITDPIFLFCDEPTTGLDSFSA 202
            |:.||..|:..:|:|:||.|.|     :.:|||||:|:|:..::|.|||.||.||||:||||.||
plant   203 KKLRVQALIDQLGIRNAAKTIIGDEGHRGISGGERRRVSIGIDIIHDPIVLFLDEPTSGLDSTSA 267

  Fly   203 YSVIKTLRHLCTRRRIAKHSLNQVYGEDSFETPSGESSASGSGSKSIEMEVVAESHESLLQTMRE 267
            :.|:|.|      :|||:                       |||
plant   268 FMVVKVL------KRIAE-----------------------SGS--------------------- 282

  Fly   268 LPALGVLSNSPNGTHKKAAICSIHQPTSDIFELFTHIILMDGGRIVYQGRTEQAAKFFTDLGYEL 332
                             ..|.|||||:..:..|...:|.:..|..|:.|.......||...|..:
plant   283 -----------------IIIMSIHQPSHRVLSLLDRLIFLSRGHTVFSGSPASLPSFFAGFGNPI 330

  Fly   333 PLNCNPADFYLKTLADKEGKENAGAVLRAKYEHETDGL--YSGSWLLARSYS------------- 382
            |.|.|..:|.|..:.:.||  :||.         |.||  ::..|...:..|
plant   331 PENENQTEFALDLIRELEG--SAGG---------TRGLVEFNKKWQEMKKQSNPQTLTPPASPNP 384

  Fly   383 ------------------------GDYLKH------VQNFKKIRWIYQVYLLMVRFMTE-----D 412
                                    ...:.|      |..|....|| ::..|..|.:..     :
plant   385 NLTLKEAISASISRGKLVSGGGGGSSVINHGGGTLAVPAFANPFWI-EIKTLTRRSILNSRRQPE 448

  Fly   413 LRNIRSGLIAFGFFMITAVTLSLMYSGIGGLTQRTVQDVGGSIFMLSNEMIFTFSYGVTYIFPAA 477
            |..:|...:....|::..|...|..|..|      ||:..|......:.|.:|.:        .|
plant   449 LLGMRLATVIVTGFILATVFWRLDNSPKG------VQERLGFFAFAMSTMFYTCA--------DA 499

  Fly   478 LP-------IIRREVGEGTYSLSAYYVALVLSFVPVAFFKGYVFLSVIYASIYY--------TRG 527
            ||       |..||.....|..|:|    |||.. :..|...:|||:.:|...:        ..|
plant   500 LPVFLQERYIFMRETAYNAYRRSSY----VLSHA-IVTFPSLIFLSLAFAVTTFWAVGLEGGLMG 559

  Fly   528 FLLYL---------SMGFLMSLSAV---AAVGYGVFLSSLFESDKMASECAAPFDLIFLIFGGTY 580
            ||.|.         ...|:..||.|   ..:||.:.::.|               ..||:|.|.:
plant   560 FLFYCLIILASFWSGSSFVTFLSGVVPHVMLGYTIVVAIL---------------AYFLLFSGFF 609

  Fly   581 MNVDTVP----GLKYLSLFFYSNEALMYKFWID-----------IDNIDCPVNE----------- 619
            :|.|.:|    ...||||..|..||::...:.|           .||  .|:.|
plant   610 INRDRIPQYWIWFHYLSLVKYPYEAVLQNEFSDPTECFVRGVQLFDN--SPLGELTYGMKLRLLD 672

  Fly   620 -----------DHPCIKTGVEVL-QQGSYRNADYTYWLDCFSLVVVAVIFHIVSFGLVRRYI 669
                       ...|:.||.:|| |||.   ...:.| :|..:.        |.||.:.|.:
plant   673 SVSRSIGMRISSSTCLTTGADVLKQQGV---TQLSKW-NCLLIT--------VGFGFLFRIL 722

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	86/293 (29%)
		3a01204	40..673	CDD:273361	183/751 (24%)
		ABC2_membrane	404..604	CDD:279410	56/235 (24%)
ABCG16	NP_191069.2	3a01204	75..735	CDD:273361	187/775 (24%)
		P-loop_NTPase	85..314	CDD:304359	86/295 (29%)
		ABC2_membrane	435..638	CDD:279410	56/236 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.880