DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bw and ABCG15

DIOPT Version :9

Sequence 1:	NP_001286769.1	Gene:	bw / 37724	FlyBaseID:	FBgn0000241	Length:	675	Species:	Drosophila melanogaster
Sequence 2:	NP_188746.2	Gene:	ABCG15 / 821661	AraportID:	AT3G21090	Length:	691	Species:	Arabidopsis thaliana

Alignment Length:	749	Identity:	184/749 - (24%)
Similarity:	318/749 - (42%)	Gaps:	191/749 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQESGGSSGQGG-PS-------LCLEWKQLNYYVPDQEQSNYSFWNECRKKRELRILQDASGHMK 57
            |:..|.|||:.. ||       ..|.|:.|...:|     |:|      .....|:||..:|:.:
plant     1 MELEGSSSGRRQLPSKLEMSRGAYLAWEDLTVVIP-----NFS------DGPTRRLLQRLNGYAE 54

  Fly    58 TGDLIAILGGSGAGKTTLLAAISQRLRGN--LTGDVVLNGMAMERHQMTRIS----SFLPQFEIN 116
            .|.::||:|.||:||:|||.:::.||..|  :||:::|||      :..|:.    :::.|.::.
plant    55 PGRIMAIMGPSGSGKSTLLDSLAGRLARNVVMTGNLLLNG------KKARLDYGLVAYVTQEDVL 113

  Fly   117 VKTFTAYEHLYFMSHFKMHRRTTKAEKRQRVADLLLAVGLRDAA-------HTRIQQLSGGERKR 174
            :.|.|..|.:.:.:|.::....:|.|....|...::.:||:|.:       |.|  .:|||||||
plant   114 LGTLTVRETITYSAHLRLPSDMSKEEVSDIVEGTIMELGLQDCSDRVIGNWHAR--GVSGGERKR 176

  Fly   175 LSLAEELITDPIFLFCDEPTTGLDSFSAYSVIKTLRHLCTRRRIAKHSLNQVYGEDSFETPSGES 239
            :|:|.|::|.|..||.||||:||||.||:.||:.||::....|
plant   177 VSIALEILTRPQILFLDEPTSGLDSASAFFVIQALRNIARDGR---------------------- 219

  Fly   240 SASGSGSKSIEMEVVAESHESLLQTMRELPALGVLSNSPNGTHKKAAICSIHQPTSDIFELFTHI 304
                                                         ..|.|:|||:|::|.||..:
plant   220 ---------------------------------------------TVISSVHQPSSEVFALFDDL 239

  Fly   305 ILMDGGRIVYQGRTEQAAKFFTDLGYELPLNCNPADFYLKTL--------ADKEGKEN------- 354
            .|:..|..||.|..:.|.:||.:.|:..|...||:|.:|:.:        |..:|.:.
plant   240 FLLSSGESVYFGEAKSAVEFFAESGFPCPKKRNPSDHFLRCINSDFDTVTATLKGSQRIQETPAT 304

  Fly   355 -------AGAVLRAK-YEHETDGLYSGSWLLARSYSGDYLKHVQNFK-KIR------WIYQVYLL 404
                   |.:|::|: .|:.....|:.|   |:|...: |.:::..: :||      |..|:..|
plant   305 SDPLMNLATSVIKARLVENYKRSKYAKS---AKSRIRE-LSNIEGLEMEIRKGSEATWWKQLRTL 365

  Fly   405 MVRFMTEDLRNIRSGLIAFGFFMITAVTLSLMYSGIGGLTQRTVQDVGGS-IFMLSNEMIFTFSY 468
            ..|......|::       |::....::..::...:|.:    ..|||.| ..:|:......|..
plant   366 TARSFINMCRDV-------GYYWTRIISYIVVSISVGTI----FYDVGYSYTSILARVSCGGFIT 419

  Fly   469 G-VTYI----FPAAL---PIIRREVGEGTYSLSAYYVALVLSFVPVAFFKGYVFLSVIYASIYYT 525
            | :|::    ||:.|   .:..:|...|.|.:|.|.::..:|..|.     .|.:|||..:|.|.
plant   420 GFMTFMSIGGFPSFLEEMKVFYKERLSGYYGVSVYILSNYISSFPF-----LVAISVITGTITYN 479

  Fly   526 RGFLLYLSMGFLMSLSAVAAVGYGVFLS-SLFESDKMASECAAPFDLIFLIFG-----------G 578
               |:....||    |..|.....:|.| |:.||..|......|..|:.||.|           |
plant   480 ---LVKFRPGF----SHYAFFCLNIFFSVSVIESLMMVVASVVPNFLMGLITGAGLIGIIMMTSG 537

  Fly   579 TYMNVDTVPGL--KY-LSLFFYSNEALMYKFWIDIDNIDC-PVNEDHPCIKTGVEVLQQGSYRNA 639
            .:..:..:|.:  :| :|...|.:.|:...:..|...::. |:....|.: ||.||:::......
plant   538 FFRLLPDLPKIFWRYPVSYISYGSWAIQGGYKNDFLGLEFEPLFPGEPKM-TGEEVIEKVFGVKV 601

  Fly   640 DYTYWLDCFSLVVVAVIFHIVSFGLVRRYIHRSG 673
            .|:.|.|..::|.:.|.:.::.| :|.:...|:|
plant   602 TYSKWWDLAAVVAILVCYRLLFF-VVLKLRERAG 634

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	81/297 (27%)
		3a01204	40..673	CDD:273361	170/700 (24%)
		ABC2_membrane	404..604	CDD:279410	51/223 (23%)
ABCG15	NP_188746.2	3a01204	41..633	CDD:273361	169/695 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770