DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bw and ABCG29

DIOPT Version :9

Sequence 1:	NP_001286769.1	Gene:	bw / 37724	FlyBaseID:	FBgn0000241	Length:	675	Species:	Drosophila melanogaster
Sequence 2:	NP_566543.1	Gene:	ABCG29 / 820881	AraportID:	AT3G16340	Length:	1416	Species:	Arabidopsis thaliana

Alignment Length:	721	Identity:	159/721 - (22%)
Similarity:	276/721 - (38%)	Gaps:	187/721 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LCLEWKQLNYYV---PDQEQSNYSFWNECRKKRELRILQDASGHMKTGDLIAILGGSGAGKTTLL 76
            |.:.:..:||||   .:.::...|       |.:|::|::.:|..:.|.|.|::|.||||||||:
plant   812 LTMSFDNVNYYVDMPKEMKEQGVS-------KDKLQLLKEVTGVFRPGVLTALMGVSGAGKTTLM 869

  Fly    77 AAISQRLRGN-LTGDVVLNGMAMERHQMTRISSFLPQFEINVKTFTAYEHLYFMSHFKMHRRTTK 140
            ..::.|..|. :.||:.::|....:....|||.:..|.:|:....|..|.|.:.:..::.:..||
plant   870 DVLAGRKTGGYIEGDIRISGFPKRQETFARISGYCEQNDIHSPQVTVKESLIYSAFLRLPKEVTK 934

  Fly   141 AEKRQ---RVADLLLAVGLRDA--AHTRIQQLSGGERKRLSLAEELITDPIFLFCDEPTTGLDSF 200
            .||.:   .|.:|:....|:||  ....|..||..:||||::|.||:.:|..:|.||||:|||:.
plant   935 YEKMRFVDEVMELVELESLKDAVVGLPGITGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDAR 999

  Fly   201 SAYSVIKTLRHLCTRRRIAKHSLNQVYGEDSFETPSGESSASGSGSKSIEMEVVAESHESLLQTM 265
            :|..|::|:|:.....|
plant  1000 AAAIVMRTVRNTVDTGR------------------------------------------------ 1016

  Fly   266 RELPALGVLSNSPNGTHKKAAICSIHQPTSDIFELFTHIILMD-GGRIVYQG----RTEQAAKFF 325
                               ..:|:||||:.||||.|..::|:. ||:::|.|    .:.:..::|
plant  1017 -------------------TVVCTIHQPSIDIFEAFDELLLLKRGGQVIYAGPLGQNSHKIIEYF 1062

  Fly   326 TDLGYELPL---NCNPADFYLKTLADKEGKENAGAVLRAKYE------HETDGLYSGSWLLARSY 381
            ..: :.:|.   ..|||.:.|         |.:.....||.|      ::|..||..:..|.:..
plant  1063 QAI-HGVPKIKEKYNPATWML---------EVSSMAAEAKLEIDFAEHYKTSSLYQQNKNLVKEL 1117

  Fly   382 SGD-------YLKH------VQNFKKIRWIYQVYLLMVRFMTEDLRNIRSGLIAFGFFMITAVTL 433
            |..       |...      :..||...|...:    ..:.|.|.     .|..|.|.:..||.|
plant  1118 STPPQGASDLYFSTRFSQSLLGQFKSCLWKQWI----TYWRTPDY-----NLARFFFTLAAAVML 1173

  Fly   434 SLMYSGIGGLTQR-TVQDVGGSIFMLSNEMIF---TFSYGVTYIFPAALPIIRREVGEGTYSLSA 494
            ..::..:|  |:| ...|:...|..:...::|   ..|..|..:......:..||.....||...
plant  1174 GSIFWKVG--TKRENANDLTKVIGAMYAAVLFVGVNNSSSVQPLIAVERSVFYRERAAEMYSALP 1236

  Fly   495 YYVALVLSFVPVAFFKGYVFLSVIYASIYYTRGFLLYLSMGFLMSLSAVAAVGYGVFLSSLFESD 559
            |.:|.|:..:|....:...:..:|||.:.:......:....|:..:|.:....||:...:|..:.
plant  1237 YALAQVVCEIPYVLIQTTYYTLIIYAMMCFEWTLAKFFWFYFVSFMSFLYFTYYGMMTVALTPNQ 1301

  Fly   560 KMASECAAPFDLIFLIFGGTYMNVDTVPGLKYLSLFFYSNEALMYKFWI---------------- 608
            ::|:..|..|..:|.:|.|..:....:|                 |:||
plant  1302 QVAAVFAGAFYGLFNLFSGFVIPRPRIP-----------------KWWIWYYWICPVAWTVYGLI 1349

  Fly   609 -----DI-DNIDCPVNEDHPCIKTGVEVLQQGSYRNADYTYWLDCFSLVVVAVIFHIVSFGLVRR 667
                 |: |.|..|...:.|.||..:|           ..|..|...::.:|.:  :|.|.|...
plant  1350 VSQYGDVEDTIKVPGMANDPTIKWYIE-----------NHYGYDADFMIPIATV--LVGFTLFFA 1401

  Fly   668 YIHRSG 673
            ::...|
plant  1402 FMFAFG 1407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	77/291 (26%)
		3a01204	40..673	CDD:273361	152/691 (22%)
		ABC2_membrane	404..604	CDD:279410	39/203 (19%)
ABCG29	NP_566543.1	PLN03140	1..1416	CDD:215599	159/721 (22%)
		ABC_trans_N	54..141	CDD:291196
		ABCG_PDR_domain1	156..402	CDD:213200
		ABC2_membrane	503..709	CDD:279410
		PDR_assoc	716..780	CDD:285559
		ABCG_PDR_domain2	811..1049	CDD:213199	82/310 (26%)
		ABC2_membrane	1144..1351	CDD:279410	43/234 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	3	2.870