Protein Alignment bw and ABCG2

DIOPT Version :9

• Sequence 1: NP_001286769.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_181272.1
• Gene: ABCG2 / 818312
• AraportID: AT2G37360
• Length: 755
• Species: Arabidopsis thaliana
• Alignment Length: 763
• Identity: 182/763 - (23%)
• Similarity: 292/763 - (38%)
• Gaps: 209/763 - (27%)

  Fly     4 SGGSSGQGGPSLCLEWKQLNYYVPDQEQSNYSFWNECRKK------RELRILQDASGHMKTGDLI 62
            |..:|........|.:..|.|.|..|::.|....  ||:.      ....:|...||..:.|:::
plant    85 SAPASSISSSPFVLSFTDLTYSVKIQKKFNPLAC--CRRSGNDSSVNTKILLNGISGEAREGEMM 147

  Fly    63 AILGGSGAGKTTLLAAISQRL-RGNLTGDVVLNGMAMERHQMTRISSFLPQFEINVKTFTAYEHL 126
            |:||.||:||:||:.|::.|: :.:|.|.:.|||..:|......||:::.|.::.....|..|.|
plant   148 AVLGASGSGKSTLIDALANRIAKDSLRGSITLNGEVLESSMQKVISAYVMQDDLLFPMLTVEETL 212

  Fly   127 YFMSHFKMHRRTTKAEKRQRVADLLLAVGLRDAAHTRI-----QQLSGGERKRLSLAEELITDPI 186
            .|.:.|::.|..:|.:|:.||..|:..:|||.||.|.|     :.:|||||:|:|:..::|.|||
plant   213 MFSAEFRLPRSLSKKKKKARVQALIDQLGLRSAAKTVIGDEGHRGVSGGERRRVSIGNDIIHDPI 277

  Fly   187 FLFCDEPTTGLDSFSAYSVIKTLRHLCTRRRIAKHSLNQVYGEDSFETPSGESSASGSGSKSIEM 251
            .||.||||:||||.|||.|||.|      :|||:                       |||
plant   278 ILFLDEPTSGLDSTSAYMVIKVL------QRIAQ-----------------------SGS----- 308

  Fly   252 EVVAESHESLLQTMRELPALGVLSNSPNGTHKKAAICSIHQPTSDIFELFTHIILMDGGRIVYQG 316
                                             ..|.|||||:..|..|...:|.:..|..||.|
plant   309 ---------------------------------IVIMSIHQPSYRIMGLLDQLIFLSKGNTVYSG 340

  Fly   317 RTEQAAKFFTDLGYELPLNCNPADFYLKTLADKE---------------------------GKEN 354
            ......:||::..:.:|.|.|..:|.|..:.:.|                           .|.|
plant   341 SPTHLPQFFSEFKHPIPENENKTEFALDLIRELEYSTEGTKPLVEFHKQWRAKQAPSYNNNNKRN 405

  Fly   355 ----------AGAVLRAKYEHETDGLYSGSWLLARSYSGDYLKHVQNFKKIRWIYQVYL----LM 405
                      ..::.|.|       |.||:   ..:.|.:.....|.|....||..:.:    ::
plant   406 TNVSSLKEAITASISRGK-------LVSGA---TNNNSSNLTPSFQTFANPFWIEMIVIGKRAIL 460

  Fly   406 VRFMTEDLRNIRSGLIAFGFFMITAVTLSLMYSGIGGLTQRTVQDVGGSIFMLSNEMIFTFSYGV 470
            ......:|..:|.|.:     |:|.:.|:.|::.:....:...:.:|...|.:|.    ||
plant   461 NSRRQPELLGMRLGAV-----MVTGIILATMFTNLDNSPKGAQERLGFFAFAMST----TF---- 512

  Fly   471 TYIFPAALP-------IIRREVGEGTYSLSAYYVALVLSFVPVAFFKGYVFLSVIYASIYY---- 524
             |....|:|       |..||.....|..|:|.::..:..:|     ..:.||..:|:..:
plant   513 -YTCAEAIPVFLQERYIFMRETAYNAYRRSSYVLSQSIISIP-----ALIVLSASFAATTFWAVG 571

  Fly   525 ----TRGFLLYLSMGFLMSLSAVAAVGYGVFLSSLFESDKMASECAAPFDLIFLIFGGTYMNVDT 585
                ..||..:.   |.:..|..|...:..|||.:..:..:...........||:|.|.:::.|.
plant   572 LDGGANGFFFFY---FTILASFWAGSSFVTFLSGVIPNVMLGFTVVVAILAYFLLFSGFFISRDR 633

  Fly   586 VP----GLKYLSLFFYSNEALMYKFWID-----------IDNI-------DCPVN---------- 618
            :|    ...|:||..|..|.::...:.:           .||.       |..||
plant   634 IPVYWLWFHYISLVKYPYEGVLQNEFQNPTRCFARGVQLFDNSPLGEFPNDVKVNLLKSMSGVLG 698

  Fly   619 ---EDHPCIKTGVEVL-QQGSYRNADYTYWLDCFSLVVVAVIFHIVSF 662
               ....|:.||:::| |||.   .|.:.| :|..:.|....|..|.|
plant   699 TNVTAETCVTTGIDILKQQGI---TDISKW-NCLWITVAWGFFFRVLF 742

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	91/296 (31%)
		3a01204	40..673	CDD:273361	174/727 (24%)
		ABC2_membrane	404..604	CDD:279410	44/218 (20%)
ABCG2	NP_181272.1	3a01204	95..754	CDD:273361	180/753 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.880