DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bw and ABCG31

DIOPT Version :9

Sequence 1:	NP_001286769.1	Gene:	bw / 37724	FlyBaseID:	FBgn0000241	Length:	675	Species:	Drosophila melanogaster
Sequence 2:	NP_180555.2	Gene:	ABCG31 / 817544	AraportID:	AT2G29940	Length:	1426	Species:	Arabidopsis thaliana

Alignment Length:	706	Identity:	165/706 - (23%)
Similarity:	275/706 - (38%)	Gaps:	186/706 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LCLEWKQLNYYVPDQEQSNYSFWNECRKKRELRILQDASGHMKTGDLIAILGGSGAGKTTLLAAI 79
            |.:.:..:||||...::.......|.|    |::|.:.||....|.|.|::|.||||||||:..:
plant   824 LTMTFHNVNYYVDMPKEMRSQGVPETR----LQLLSNVSGVFSPGVLTALVGSSGAGKTTLMDVL 884

  Fly    80 SQRLRGNLT-GDVVLNGMAMERHQMTRISSFLPQFEINVKTFTAYEHLYFMSHFKMHRRTTKAEK 143
            :.|..|..| ||:.::|...|:....|||.::.|.:|:....|..|.|:|.:..::.:..||.:|
plant   885 AGRKTGGYTEGDIRISGHPKEQQTFARISGYVEQNDIHSPQVTVEESLWFSASLRLPKEITKEQK 949

  Fly   144 RQRVADLLLAVGLRDAAHTRI-----QQLSGGERKRLSLAEELITDPIFLFCDEPTTGLDSFSAY 203
            ::.|..::..|.|....:..:     ..||..:||||::|.||:.:|..:|.||||:|||:.:|.
plant   950 KEFVEQVMRLVELDTLRYALVGLPGTTGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAA 1014

  Fly   204 SVIKTLRHLCTRRRIAKHSLNQVYGEDSFETPSGESSASGSGSKSIEMEVVAESHESLLQTMREL 268
            .|::|:|:.....|
plant  1015 IVMRTVRNTVDTGR--------------------------------------------------- 1028

  Fly   269 PALGVLSNSPNGTHKKAAICSIHQPTSDIFELFTHIILMD-GGRIVYQGR----TEQAAKFFTDL 328
                            ..:|:||||:.||||.|..::||. ||:::|.|:    ::....:|..:
plant  1029 ----------------TVVCTIHQPSIDIFEAFDELLLMKRGGQVIYGGKLGTHSQVLVDYFQGI 1077

  Fly   329 GYELPLNC--NPADFYLKTLADKEGKENAGAVLRAKYEHETDGLYSGSWLLARSYSGDYLKHVQ- 390
            ....|::.  |||.:.|         |.....|..||..|...||..|         |..:.|:
plant  1078 NGVPPISSGYNPATWML---------EVTTPALEEKYNMEFADLYKKS---------DQFREVEA 1124

  Fly   391 NFKKI------------------RWIYQVYLLMVRFMTEDLRNIRSGLIAFGFFMITAVTLSLMY 437
            |.|::                  ..:.|..|.:.:......|:....|:...|..|.|..|..::
plant  1125 NIKQLSVPPEGSEPISFTSRYSQNQLSQFLLCLWKQNLVYWRSPEYNLVRLVFTTIAAFILGTVF 1189

  Fly   438 SGIGGLTQRT-VQD---VGGSIFMLSNEMIFTFSYGVTYIFPAALPIIRREVGEGTYSLSAYYVA 498
            ..||  ::|| .||   |.|:::.....:..:.:..|..|......:..||...|.|:...|..|
plant  1190 WDIG--SKRTSSQDLITVMGALYSACLFLGVSNASSVQPIVSIERTVFYREKAAGMYAPIPYAAA 1252

  Fly   499 LVLSFVPVAFFKGYVFL-SVIYASI-YYTRG-------FLLYLSMGFLMSLSAVAAVGYGVFLSS 554
            ..|..:|      |:.. :::|..| |:|.|       |:|||   ..|.|:......||:....
plant  1253 QGLVEIP------YILTQTILYGVITYFTIGFERTFSKFVLYL---VFMFLTFTYFTFYGMMAVG 1308

  Fly   555 LFESDKMASECAAPFDLIFLIFGGTYMNVDTVPGLKYLSLFFYSNEALMYKFWIDIDNIDCPVNE 619
            |..:..:|:..::.|..::.:..|                 |...:.|:..:||....| |||
plant  1309 LTPNQHLAAVISSAFYSLWNLLSG-----------------FLVQKPLIPVWWIWFYYI-CPV-- 1353

  Fly   620 DHPCIKTGVEVLQQGSYRNADYTYWLDCFSLVVVAVIFHIVSFGLVRRYIHRSGYY 675
              .....||.:.|.|...:            ::...:||    |.|:.:|.   ||
plant  1354 --AWTLQGVILSQLGDVES------------MINEPLFH----GTVKEFIE---YY 1388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	78/291 (27%)
		3a01204	40..673	CDD:273361	157/677 (23%)
		ABC2_membrane	404..604	CDD:279410	44/212 (21%)
ABCG31	NP_180555.2	PLN03140	17..1426	CDD:215599	165/706 (23%)
		ABC_trans_N	77..151	CDD:291196
		ABCG_PDR_domain1	155..416	CDD:213200
		ABC2_membrane	517..723	CDD:279410
		PDR_assoc	730..793	CDD:285559
		ABCG_PDR_domain2	823..1061	CDD:213199	83/307 (27%)
		ABC2_membrane	1156..1361	CDD:279410	51/237 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	3	2.870