Protein Alignment bw and Abca14

DIOPT Version :9

• Sequence 1: NP_001286769.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: XP_017167760.1
• Gene: Abca14 / 67928
• MGIID: 2388708
• Length: 1719
• Species: Mus musculus
• Alignment Length: 729
• Identity: 140/729 - (19%)
• Similarity: 254/729 - (34%)
• Gaps: 243/729 - (33%)

  Fly    42 KKRELRILQDASGHMKTGDLIAILGGSGAGKTTLLAAISQRLRGNLTGDVVLNG--MAMERHQMT 104
            |...|..:.|.|.::..|.:..:||.:||||||.|:.:: .|.....|.|.::|  ::.:..|:.
Mouse   568 KNSTLMAVNDLSLNLYEGQITVLLGHNGAGKTTTLSILT-GLYLPTRGKVYISGYDISSDMVQIR 631

  Fly   105 RISSFLPQFEINVKTFTAYEHLYFMSHFKMHRRTTKAEKRQRVADLLLAVGLRDAAHTRIQQLSG 169
            :.....||.::.....|..|||:|....|......::.:..|   :|.:.||...::|..:.|||
Mouse   632 KSLGLCPQDDLLFPMLTVSEHLHFYCVIKGIPLQNQSRETNR---MLTSFGLLQQSNTMSKDLSG 693

  Fly   170 GERKRLSLAEELITDPIFLFCDEPTTGLDSFSAYSVIKTLRHLCTRRRI--AKHSLNQVYGEDSF 232
            |.:::||:...||.|...:..||||:|:|..|..:....|:|....|.|  ..|.::
Mouse   694 GMKRKLSIIIALIGDTKVVILDEPTSGMDPVSRRATWDLLQHYKKDRTILLTTHHMD-------- 750

  Fly   233 ETPSGESSASGSGSKSIEMEVVAESHESLLQTMRELPALG---VLSNSPNGTHKKAAICSIHQPT 294
                 |:...|.....:.|.::.....||.  :::|..:|   |:..:|:...:|
Mouse   751 -----EADVLGDRIAILVMGILKCCGSSLF--LKKLYGVGYHLVIVKTPDSNDEK---------- 798

  Fly   295 SDIFELFTHII---------LMDGGRIVYQGRTEQAAKFFTDL----------GYELPLN----- 335
              ||:|..:.|         ..:...|:.:..|.:.|:.||||          |:.:.:.
Mouse   799 --IFQLIKNYIPTAKMETNVAAELSFILPKEHTHRFAELFTDLEEKQEELGISGFGVSMTTMDEV 861

  Fly   336 ----CNPADFYLKT--------LADKEGKENAGAVLRAKYE------HETDGLYSGSW-LLARSY 381
                .|..|..|.|        ::....::|....:...:|      ...|..::..| |..:.:
Mouse   862 FFKVSNLEDLKLNTEIAPSASIVSQSSNEDNQNMNVPRNFERPGYSRRHLDSSFNAGWSLYIQQF 926

  Fly   382 SGDYLKHVQNFKKIRWIY-------------QVYLL----------------------------- 404
            ...::|.|.    ..|.|             .:|||
Mouse   927 RAMFIKRVM----FSWRYWKLLLLQLLALLGLMYLLIKGISFSVPKEPARVMDLEQYGETIVPFS 987

  Fly   405 ------MVRFMTE------------------DLRN--------IRSGLIAFGFFMIT-------- 429
                  :.:.:|:                  |::|        |.|.::||...:.|
Mouse   988 VSGDPNLTQILTKNLETMLKAKKQKIHEVQGDMKNYLLTSKDCIYSCIVAFSLDVTTEEKTFIFW 1052

  Fly   430 -------AVTLSL------MYSGIGG----LT-------QRTVQDVGGSIFMLSNEMIFTFSYGV 470
                   |..|||      :|..:.|    :|       ||..:|......:...:::|...:|:
Mouse  1053 FNNEAYHAAPLSLSILDNIIYKYLSGPDATITVSNNPQPQRVTKDKSNERSISGIQIVFNLLFGM 1117

  Fly   471 TYIFPA--ALPIIRREVGE--------GTYSLSAYYVALVLSFVPVAFFKGYVFLSVIYASIYYT 525
            : ||.:  .|..:...|.:        |.|:|:.:..||:...  :..|...|.|.|::
Mouse  1118 S-IFTSGFCLMTVTERVSKAKHIQFVSGVYTLNFWLSALLWDL--IIHFVACVLLLVVF------ 1173

  Fly   526 RGFLLYLSMGFLMSLSAVAAVGYGVFLSSLFESDKMASECAAPFDLIFLIFGGTYMNVDTVPGLK 590
                ||..:..|:....        ||.::|               |.::||.:     .:|.:
Mouse  1174 ----LYTDVDILLEKYH--------FLDTMF---------------ILMLFGWS-----IIPFI- 1205

  Fly   591 YLSLFFYSNEALMY 604
            ||..|:|:|....|
Mouse  1206 YLLSFWYNNSTNAY 1219

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	68/289 (24%)
		3a01204	40..673	CDD:273361	140/729 (19%)
		ABC2_membrane	404..604	CDD:279410	49/302 (16%)
Abca14	XP_017167760.1	rim_protein	<128..1709	CDD:130324	140/729 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000