Protein Alignment bw and abcg2b

DIOPT Version :9

• Sequence 1: NP_001286769.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_001034155.1
• Gene: abcg2b / 570453
• ZFINID: ZDB-GENE-050517-36
• Length: 618
• Species: Danio rerio
• Alignment Length: 722
• Identity: 185/722 - (25%)
• Similarity: 303/722 - (41%)
• Gaps: 194/722 - (26%)

  Fly    13 PSLCLEWKQLNYYVPDQEQSNYSFWNECRKKRELRILQDASGHMKTGDLIAILGGSGAGKTTLLA 77
            |...|.::.::|.:  :|.....    |:|..|..||::.||.|||| |.||:|.:|:|||:||.
Zfish    24 PGPILTYQNIHYCI--RESRGLC----CKKAPERDILKNVSGIMKTG-LNAIMGATGSGKTSLLD 81

  Fly    78 AISQRL--RGNLTGDVVLNGMAMERHQMTRISSFLPQFEINVKTFTAYEHLYFMSHFKMHR-RTT 139
            .::.|.  ||..:|.|:::. .:....:..:|:::.|.::.:.|.|..|:|.|..:.::.| :.:
Zfish    82 VMAGRKDPRGLRSGQVLVDN-KLVTSDLRLMSAYVVQDDVLMGTLTVRENLLFSGNLRLPREQFS 145

  Fly   140 KAEKRQRVADLLLAVGLRDAAHTR-----IQQLSGGERKRLSLAEELITDPIFLFCDEPTTGLDS 199
            .|:|:::|..::..:||.|.|.|:     |:.:|||||||.|:..||||.|..||.|||||||||
Zfish   146 SADKKKKVESIIEELGLEDCADTKIGTEFIRGVSGGERKRCSIGMELITSPTLLFLDEPTTGLDS 210

  Fly   200 FSAYSVIKTLRHLCTRRRIAKHSLNQVYGEDSFETPSGESSASGSGSKSIEMEVVAESHESLLQT 264
            .:|.|:|..|           |.|::                   |.::|
Zfish   211 NTANSIIALL-----------HRLSR-------------------GGRTI--------------- 230

  Fly   265 MRELPALGVLSNSPNGTHKKAAICSIHQPTSDIFELFTHIILMDGGRIVYQGRTEQAAKFFTDLG 329
                                  |.|||||...||.||.::.||..|..||.|...:|..:|..||
Zfish   231 ----------------------IFSIHQPRYSIFRLFDYLTLMHKGETVYAGPAGKAIDYFQSLG 273

  Fly   330 YELPLNCNPADFYL--------------KTLA------------DKEGKENAGAVLRAKYEHETD 368
            ||.....|||||:|              |:||            |:|.|...|.
Zfish   274 YERDAFNNPADFFLDITNGETATSMPTEKSLAELYRESQFCTAVDEELKCITGP----------- 327

  Fly   369 GLYSGSWLLARSYSGDYLKHVQNFKKIRWIYQVYLLMVRFMTEDLRNIRSGLIAFGFFMITAVTL 433
               |.|...|:|.:..|   |.:|.     ||:.::..|.....:||.::........::.|:.:
Zfish   328 ---SDSLSEAKSKAPSY---VTSFS-----YQLKVVCWRTGLNVVRNPQTSYAQIAMNILFALLI 381

  Fly   434 SLMYSGIGGLTQRTVQDVGGSIFMLSNEMIFTFSYGVTYIFPAALPIIRREVGEGTYSLSAYYVA 498
            .|:|..:.......:|:..|:.|.|...|:|. :.....:|.....|...|...|.|..|.|:::
Zfish   382 GLVYYQMPLTLPEALQNRIGAFFFLIINMVFG-NLSAVELFINERAIFVHENSGGYYRTSVYFLS 445

  Fly   499 LVL------SFVPVAFFKGYVFLSVIYASI-YYTRG----FLLYLSMGFLMSLSAVAAVGYGVFL 552
            .|.      ..||:          :|::|| ||..|    |..:|.....:||.::|.|.....:
Zfish   446 KVFVDLLPNRIVPI----------LIFSSISYYMMGLNPAFTSFLCFALTVSLVSLAGVSLAFLV 500

  Fly   553 SSLFESDKMASECAA-PFDLIFLIFGGTYMNVDT----VPGLKYLSLFFYSNEALMYKFWIDIDN 612
            |:...:..||:.... || :..::|||..:|:::    :..||:.|:|.|..:|:
Zfish   501 SASVSTFAMANILVVLPF-VFMMVFGGFLVNLNSMLNWLSWLKWTSIFKYGLDAV---------- 554

  Fly   613 IDCPVNEDHPCIKTGVEVLQQGS----------YRNADYTYW------LDCFSLVVVAVIFHIVS 661
               .:||     ..|: ||..|:          .:..||:.|      :....:|:|.:.|..:.
Zfish   555 ---TINE-----MKGL-VLYSGNATLPGELYLESQGIDYSVWGFWQNEVALLGIVLVCMTFAYIQ 610

  Fly   662 FGLVRRY 668
            ...:.|:
Zfish   611 LRRINRW 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	90/292 (31%)
		3a01204	40..673	CDD:273361	181/695 (26%)
		ABC2_membrane	404..604	CDD:279410	49/215 (23%)
abcg2b	NP_001034155.1	P-loop_NTPase	39..260	CDD:304359	91/293 (31%)
		3a01204	41..616	CDD:273361	180/700 (26%)
		ABC2_membrane	354..557	CDD:279410	49/227 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820