Protein Alignment bw and abcg5

DIOPT Version :9

• Sequence 1: NP_001286769.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_001122162.1
• Gene: abcg5 / 557317
• ZFINID: ZDB-GENE-050517-40
• Length: 652
• Species: Danio rerio
• Alignment Length: 703
• Identity: 177/703 - (25%)
• Similarity: 292/703 - (41%)
• Gaps: 136/703 - (19%)

  Fly    13 PSLCLEWKQLNYYVPDQEQSNYSFW--NECRKKRELRILQDASGHMKTGDLIAILGGSGAGKTTL 75
            ||.||..|.::|.|.::..   .:|  :..|||...:||.:.|.|:.:|.::.|||.||:|||||
Zfish    38 PSSCLSVKNVSYSVSERVG---PWWDLSSFRKKWTRQILNEVSFHLDSGQIMGILGNSGSGKTTL 99

  Fly    76 LAAISQRL--RGNLTGDVVLNGMAMERHQMTRISSFLPQFEINVKTFTAYEHLYFMSHFKMHRRT 138
            |.||:.|:  .|||.|:|.:||..::|.|.....|::.|.:..:...|..|.|.:.:...:.:.:
Zfish   100 LDAIAGRIGNSGNLQGEVFVNGRKLKREQFQDCFSYVLQSDNLLSYLTVEETLTYTAQLALRKHS 164

  Fly   139 TKAEKRQRVADLLLAVGLRDAAHTRI-----QQLSGGERKRLSLAEELITDPIFLFCDEPTTGLD 198
            .:| .|::|..::..:.|...||:.|     ..:|||||:|:|:|.:|:.||..:..||||||||
Zfish   165 AEA-IRKKVTAVMAELSLGHVAHSVIGGRVFPGISGGERRRVSIASQLLQDPKVILLDEPTTGLD 228

  Fly   199 SFSAYSVIKTLRHLCTRRRIAKHSLNQVYGEDSFETPSGESSASGSGSKSIEMEVVAESHESLLQ 263
            |.:|..::..|..|..|.||
Zfish   229 SMTANQIVMLLAELARRDRI--------------------------------------------- 248

  Fly   264 TMRELPALGVLSNSPNGTHKKAAICSIHQPTSDIFELFTHIILMDGGRIVYQGRTEQAAKFFTDL 328
                                  .|.:||||.|::|.:|..|.:|..|.:|:.|...:...||:..
Zfish   249 ----------------------VIVTIHQPRSELFRIFNRIAIMSQGELVFCGEPHKMVDFFSSC 291

  Fly   329 GYELPLNCNPADFYLK-TLADKEGKENAGAVLRAKYEHETDGLYSGSWLLARSYSGDYLKHVQN- 391
            |||.|..|||.|.|:. |..|....|...|..|..  |:....|..|.:    |:....|..|:
Zfish   292 GYECPEYCNPFDIYVDLTSVDTRCSEREAATYRRM--HDITSAYQNSEI----YTNMQEKIEQSC 350

  Fly   392 ---------FK---KIRWIYQVYLLMVRFMTEDLRNI---RSGL-------IAFGFFMITAVTLS 434
                     ||   ....|.::.:|:.|    ..||:   |.|:       :.:|.|    :...
Zfish   351 QRPDKPMIPFKSKESPNCISKLGVLLRR----TFRNVSRDRMGILMRLSQNLIYGLF----IAFF 407

  Fly   435 LMYSGIGGLTQRTVQDVGGSIFMLSNEMIFTFSYGVTYIFPAALPIIRREVGEGTYSLSAYYVAL 499
            ||..| ..:|:..|||..|.|:.......:|.......:|||...|..:|..:|.|.....::|.
Zfish   408 LMRLG-KDVTKGAVQDRIGLIYQSMGASPYTGMLNAVALFPALRAISDQESKDGLYQKWQMFLAY 471

  Fly   500 VLSFVPVAFFKGYVFLSVIYASIYYTRGFLLYLSMGFLMSLSAVAAVGYGVFLSSLFESDKMASE 564
            ::..:|.:....::|.|.:|.::......:.:|....::.:..:......:.|..:.:...|.:.
Zfish   472 IIHILPFSIISVFIFASFLYWTVGMNPDPVRFLCFSAVVMVPHIIGELLTLVLLGVVQDPNMVNS 536

  Fly   565 CAAPFDLIFLIFGGTYM-NVDTVP----GLKYLSLFFYSNEALMYKFWIDIDNIDCPVNEDHP-- 622
            ..|..::..::.|..:: ....:|    .|.||:...|..|.|:...:..: |..|......|
Zfish   537 GVALLNIAGIMVGSGFLRGFKQMPVVFQWLSYLTFQKYGCELLIVTEFYGL-NFTCTPIAGLPGE 600

  Fly   623 C-IKTGVEVLQQGSYRNADYTYWLD---CFSLVVVAVIFHIVSF----GLVRR 667
            | :.:|..::.|| |..|...|..|   .::.:...||..|:||    .||||
Zfish   601 CLVDSGNMIIDQG-YPGALSRYTQDFLLLYAFLPALVILGIISFKIRDHLVRR 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	82/293 (28%)
		3a01204	40..673	CDD:273361	169/674 (25%)
		ABC2_membrane	404..604	CDD:279410	42/214 (20%)
abcg5	NP_001122162.1	3a01204	50..645	CDD:273361	167/682 (24%)
		ABCG_White	53..279	CDD:213201	82/296 (28%)
		ABC2_membrane	375..582	CDD:279410	42/215 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920