DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bw and Atet

DIOPT Version :9

Sequence 1:	NP_001286769.1	Gene:	bw / 37724	FlyBaseID:	FBgn0000241	Length:	675	Species:	Drosophila melanogaster
Sequence 2:	NP_001097079.1	Gene:	Atet / 33636	FlyBaseID:	FBgn0020762	Length:	832	Species:	Drosophila melanogaster

Alignment Length:	813	Identity:	182/813 - (22%)
Similarity:	307/813 - (37%)	Gaps:	249/813 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SGGS-SGQ-----------GGPSLCLEWKQLNYYVPDQEQSNYSFWNECRKKRELRILQDASGHM 56
            |||| :||           ..|.:.:|:..::|.|.|..:..:.           .||:..||..
  Fly   120 SGGSPNGQKKGTIALSHLPQRPPVDIEFCDISYSVTDSHRRGFK-----------TILKSVSGKF 173

  Fly    57 KTGDLIAILGGSGAGKTTLLAAISQRLRGNLTGDVVLNGMAMERHQMTRISSFLPQFEINVKTFT 121
            :.|::.||:|.|||||:||:..::......|:|.|::|.......:..::|.::.|.::.:...|
  Fly   174 RNGEITAIMGPSGAGKSTLMNILAGYKTAQLSGSVLINSKERNLRRFRKLSCYIMQDDVLIANLT 238

  Fly   122 AYEHLYFMSHFKMHRRTTKAEKRQRVADLLLAVGLRDAAHTRIQQLSGGERKRLSLAEELITDPI 186
            ..|.:...::.|:.:......|...|.::|..:||:::.:|....||||:|||||:|.||:.:|.
  Fly   239 VREAMMVAANLKLGKNMISYAKVVVVEEILETIGLKESVNTLTCNLSGGQRKRLSIALELVNNPP 303

  Fly   187 FLFCDEPTTGLDSFSAYSVIKTLRHLCTRRRIAKHSLNQVYGEDSFETPSGESSASGSGSKSIEM 251
            .:|.||||:||||.:.:.:|..||.|                              ..|.::|
  Fly   304 VMFFDEPTSGLDSSTCFQLISLLRSL------------------------------ARGGRTI-- 336

  Fly   252 EVVAESHESLLQTMRELPALGVLSNSPNGTHKKAAICSIHQPTSDIFELFTHIILMDGGRIVYQG 316
                                               :|:||||::.:||.|.|:.|:..|:.||:|
  Fly   337 -----------------------------------VCTIHQPSARLFEKFDHLYLLAQGQCVYEG 366

  Fly   317 RTEQAAKFFTDLGYELPLNCNPADF--------------------------------YLKTLADK 349
            |.:....:.:.||||.|...||||:                                |:.|||.|
  Fly   367 RVKGLVPYLSSLGYECPSYHNPADYVLEVASGEYGDAVPKLVDAVKSGACKKYAHKDYVLTLAQK 431

  Fly   350 -----------EGKENAGAVLRAKYEHE------------------------------------- 366
                       .|.|||.|:|..:.|..
  Fly   432 GCNNDIIKGSGSGAENAMAILTLEDEKPPLEDRQLEPSIPVDDPAELKPPKLETQQSQNSDCSVV 496

  Fly   367 ------------------TDGLYSGSW-------------LLARSYSGDYLKHVQNFKKIRWIYQ 400
                              |.....||.             ||....|...|.:...|....|. |
  Fly   497 NMPTNAVDDSCSFSSSKGTQNAVGGSGSGGPSAVVGCMTSLLDSHESVVTLPNKTGFPTSGWT-Q 560

  Fly   401 VYLLMVRFMTEDLRN-IRSGLIAFGFFMITAVTLSLMYSGIGGLTQRTVQDVGGSIFMLSNEMIF 464
            .::|:.|.....||: :.:.:..|...::.|: :.::|..:|....:.:.: .|.||.:|....|
  Fly   561 FWILLKRSFRTILRDKMLTHMRLFSHVIVGAI-IGMIYYDVGNEASKIMSN-AGCIFFVSLFTTF 623

  Fly   465 TFSYGVTYIFPAALPIIRREVGEGTYSLSAYYVALVLSFVPVAFFKGYVFLSVIYASIYYTRG-- 527
            |........||..:.:..||.....|||.|:|.|..::.:|...    ||.||....:||...
  Fly   624 TAMMPTILTFPTEMSVFVREHLNYWYSLKAFYFAKTIADMPFQI----VFSSVYVLVVYYLTSQP 684

  Fly   528 --------FLLYLSMGFLMSLSAVAAVG------YGVFLSSLFESDKMASECAAPFDLI-FLIFG 577
                    |:|...:..|::.|....:|      .||||              .|...| .::|.
  Fly   685 MELERVSMFVLICVLNSLVAQSLGLLIGAGMNIETGVFL--------------GPVTTIPTILFS 735

  Fly   578 GTYMNVDTVPG----LKYLSLFFYSNEALMYKFW-IDIDNIDCPVNEDHPCIKTGVEVLQQGSYR 637
            |.::|.||:||    :.|:|...|..|..|...: :|...:.|  |:.:...:...:.|::.|..
  Fly   736 GFFVNFDTIPGYLQWVTYVSYVRYGFEGAMVAIYGMDRAKMQC--NQMYCHYRVPKKFLEEMSMD 798

  Fly   638 NADYTYWLDCFSLVVVAVIFHIVSFGLVRRYIH 670
            ||  .:|:|..:|:.:.....|:::.::|..:|
  Fly   799 NA--LFWVDAVALIGIFFALRIIAYFVLRWKLH 829

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	71/284 (25%)
		3a01204	40..673	CDD:273361	171/765 (22%)
		ABC2_membrane	404..604	CDD:279410	53/221 (24%)
Atet	NP_001097079.1	3a01204	137..825	CDD:273361	174/790 (22%)
		ABCG_EPDR	142..366	CDD:213180	75/301 (25%)
		ABC2_membrane	564..767	CDD:279410	54/222 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm14984
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.910