DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment bw and CG9664

DIOPT Version :9

Sequence 1:	NP_001286769.1	Gene:	bw / 37724	FlyBaseID:	FBgn0000241	Length:	675	Species:	Drosophila melanogaster
Sequence 2:	NP_722889.1	Gene:	CG9664 / 33540	FlyBaseID:	FBgn0031515	Length:	609	Species:	Drosophila melanogaster

Alignment Length:	705	Identity:	168/705 - (23%)
Similarity:	298/705 - (42%)	Gaps:	147/705 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ESGGSSGQGGPSLCLEWKQLNYYVPDQEQSNYSFWNECRKKRELRILQDASGHMKTGDLIAILGG 67
            :..|...|...:|.|.:.|::|.:            :...|....|:.:|.|..|:|.|.||||.
  Fly     9 QPNGLGPQKQKALELHFSQVSYSL------------KGATKGSTPIINEACGVFKSGRLTAILGP 61

  Fly    68 SGAGKTTLLAAISQ-RLRGNLTGDVVLNGMAMERHQMTRISSFLPQFEINVKTFTAYEHLYFMSH 131
            |||||:|||.|::. :|:| :||..:|||...:.....::|:::.|..:.:...|..|.|...:.
  Fly    62 SGAGKSTLLNALAGFKLQG-VTGQFLLNGRPRDIMSFRKMSAYIAQNFVMLNLLTVEETLRVSTD 125

  Fly   132 FKMHRRTTKAEKRQRVADLLLAVGLRDAAHTRIQQLSGGERKRLSLAEELITDPIFLFCDEPTTG 196
            .||...|...||::.:.|::..:.|:....|.::.|||||.||||:..||:|:|..:|.||||:|
  Fly   126 LKMPSSTAAQEKQKIIDDIIDILQLQSCRRTLVKNLSGGEHKRLSIGIELVTNPPIMFFDEPTSG 190

  Fly   197 LDSFSAYSVIKTLRHLCTRRRIAKHSLNQVYGEDSFETPSGESSASGSGSKSIEMEVVAESHESL 261
            ||...:|.||      |..:|:|                                      |:.
  Fly   191 LDCVGSYQVI------CHLQRLA--------------------------------------HDG- 210

  Fly   262 LQTMRELPALGVLSNSPNGTHKKAAICSIHQPTSDIFELFTHIILMDGGRIVYQGRTEQAAKFFT 326
                                  :..:|.:|||.|.:|:||..::::..|.::|.|...:....|.
  Fly   211 ----------------------RIVVCVVHQPGSRLFQLFDDVLVLAHGEVLYAGEQREMLPTFA 253

  Fly   327 DLGYELPLNCNPADFYLKTLADKEGKE--------------NAGAVLRAKYEHET-------DGL 370
            ..|:..|...|||||.|:..:.....|              .|..|::.:.:.||       |.|
  Fly   254 QSGHICPQYYNPADFALEVCSQSSTTERCESLITQNKMMHSTASNVVKLQVDEETALIDVHKDAL 318

  Fly   371 YSGSWLLARSYSGDYLKHVQNFKKIRWIYQVYLLM---VRFMTEDLRNIRSGLIAFGFFMITAVT 432
                          .|.|::..:::.:..|:.:|:   :|.|:.|:..::..|:   ..::.|:.
  Fly   319 --------------DLSHLRGKEQVGFWTQLSVLLRRHLRSMSRDMFAVQMRLV---MHVVVALL 366

  Fly   433 LSLMYSGIGGLTQRTVQDVGGSIFMLSNEMIFTFSYGVTYIFPAAL------PIIRREVGEGTYS 491
            |.::|..|||..|:.|.:|....|::    :|.|:...   .|:.|      .:..||...|.||
  Fly   367 LGVVYWQIGGDAQKIVSNVSCLFFVI----LFVFAGNA---MPSILLCMQDSAVFIREYYNGWYS 424

  Fly   492 LSAYYVALVLSFVPVAFFKGYVFLSVIYASIYYTRGFLLYLSMGFLMSLSAVAAVGYGVFLSSLF 556
            |.|||::.||:.:|:......:|:|:.|........|..:.....|..::|......||...|||
  Fly   425 LGAYYLSKVLADLPLQLTCPTMFISIGYFMTGQPPEFQRFAMCWALCVMTAFIGHFIGVIAGSLF 489

  Fly   557 ESDKMASECAAPFDLIFLIFGGTYMNVDTVP----GLKYLSLFFYSNEALMYKFW-IDIDNIDCP 616
             :.::|........:.||:|.|.::.::.:.    .:..:|.|.|..|.||...: .|...::|.
  Fly   490 -TMQLAIFLVPSATIPFLLFSGFFIRLNELSWFLRPICDVSFFRYIFEGLMRAIYGYDRGELECY 553

  Fly   617 VNEDHPCIKTGVEVLQQGSYRNADYTYW----LDCFSLVVVAVIFHIVSFGLVRR 667
            ...:....:|..:.|:.......::. |    |..| |:::.:.|.:....::||
  Fly   554 ATSNFCYYRTAEQFLKDFQMEGNEFD-WDMAVLGIF-LILLLLAFFVTLNAVIRR 606

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	78/285 (27%)
		3a01204	40..673	CDD:273361	162/668 (24%)
		ABC2_membrane	404..604	CDD:279410	52/212 (25%)
CG9664	NP_722889.1	ABCG_EPDR	20..243	CDD:213180	82/302 (27%)
		EcfA2	23..247	CDD:224047	82/303 (27%)
		ABC2_membrane	338..539	CDD:279410	51/211 (24%)
		YadH	<388..547	CDD:223912	39/166 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm14984
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920