DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bw and AgaP_AGAP009470

DIOPT Version :9

Sequence 1:	NP_001286769.1	Gene:	bw / 37724	FlyBaseID:	FBgn0000241	Length:	675	Species:	Drosophila melanogaster
Sequence 2:	XP_559779.3	Gene:	AgaP_AGAP009470 / 3291976	VectorBaseID:	AGAP009470	Length:	226	Species:	Anopheles gambiae

Alignment Length:	226	Identity:	53/226 - (23%)
Similarity:	88/226 - (38%)	Gaps:	37/226 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   457 MLSNE------MIFTF---SYGVTYIFPAALPIIRREVGEGTYSLSAYYVALVLSFVPVAFFKGY 512
            ||||.      :||.|   |..:...||....:..||.....|||.|||.:.:::..|.......
Mosquito     1 MLSNASCLFFFLIFVFFANSMPLVMTFPLETSVFVRERMNNWYSLKAYYFSKLVADFPFLILGPS 65

  Fly   513 VFLSVIYASIYYTRGFLLYLSMGFLMSLSAVAAVGYGVFLSSLFESDKMASECAAPFDL-IF--- 573
            |||    |..||.....:.|..  ::.|.::.     :|.|.:.:...:.:....|.:| :|
Mosquito    66 VFL----AGAYYLTSQPMELDR--IVMLWSIC-----IFTSWIAQMTGLLAGSVLPLELSVFCVP 119

  Fly   574 ------LIFGGTYMN----VDTVPGLKYLSLFFYSNEALMYKFWIDIDNIDCPVNEDHPCIKTGV 628
                  |||.|.::.    .|.:....|::.|.||.|..|...: ..|..:.|.:.|. |..:.|
Mosquito   120 CSVIPMLIFCGFFVRFREMFDFLIPFTYVAYFRYSFEGAMQAIY-GFDRANLPCSGDF-CYFSKV 182

  Fly   629 EVLQQGSYRNADYTYWLDCFSLVVVAVIFHI 659
            ..... |:...:.|:.:|...|:....:.|:
Mosquito   183 PKFLD-SFDMLENTFVMDVCGLLGWIFVLHV 212

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359
		3a01204	40..673	CDD:273361	53/226 (23%)
		ABC2_membrane	404..604	CDD:279410	42/169 (25%)
AgaP_AGAP009470	XP_559779.3	ABC2_membrane	<18..161	CDD:279410	36/153 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900