Protein Alignment bw and Abcg2

DIOPT Version :9

• Sequence 1: NP_001286769.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_852046.1
• Gene: Abcg2 / 312382
• RGDID: 631345
• Length: 657
• Species: Rattus norvegicus
• Alignment Length: 735
• Identity: 179/735 - (24%)
• Similarity: 297/735 - (40%)
• Gaps: 187/735 - (25%)

  Fly     6 GSSGQGGPSLC----LEWKQLNYYVPDQEQSNYSFWNECRKKRELRILQDASGHMKTGDLIAILG 66
            |.|.:|..:|.    |.:..:.|.|  :.:|.:.    .||..|..||.|.:|.||.| |.||||
  Rat    22 GMSSRGARTLAEGDVLSFHHITYRV--KVKSGFL----VRKTAEKEILSDINGIMKPG-LNAILG 79

  Fly    67 GSGAGKTTLLAAISQRL--RGNLTGDVVLNGMAMERHQMTRISSFLPQFEINVKTFTAYEHLYFM 129
            .:|.||::||..::.|.  || |:|||::|| |.:.......|.::.|.::.:.|.|..|:|.|.
  Rat    80 PTGGGKSSLLDVLAARKDPRG-LSGDVLING-APQPANFKCSSGYVVQDDVVMGTLTVRENLQFS 142

  Fly   130 SHFKMHRRTTKAEKRQRVADLLLAVGLRDAAHTRI-----QQLSGGERKRLSLAEELITDPIFLF 189
            :..::.:.....||.:|:..::..:||...|.:::     :.:|||||||.|:..||||||..||
  Rat   143 AALRLPKAMKTHEKNERINTIIKELGLDKVADSKVGTQFTRGISGGERKRTSIGMELITDPSILF 207

  Fly   190 CDEPTTGLDSFSAYSVIKTLRHLCTRRRIAKHSLNQVYGEDSFETPSGESSASGSGSKSIEMEVV 254
            .|||||||||.:|.:|:..|      :|::|..
  Rat   208 LDEPTTGLDSSTANAVLLLL------KRMSKQG-------------------------------- 234

  Fly   255 AESHESLLQTMRELPALGVLSNSPNGTHKKAAICSIHQPTSDIFELFTHIILMDGGRIVYQGRTE 319
                                         :..|.|||||...||:||..:.|:..|::::.|..:
  Rat   235 -----------------------------RTIIFSIHQPRYSIFKLFDSLTLLASGKLMFHGPAQ 270

  Fly   320 QAAKFFTDLGYEL-PLNCNPADFYLKTLADKEGKENAGAVLRAKYEHETD--------------- 368
            :|.::|...||.. |.| |||||:|..:   .|..:|..:.|.:.:||.:
  Rat   271 KALEYFASAGYHCEPYN-NPADFFLDVI---NGDSSAVMLNRGEQDHEANKTEEPSKREKPIIEN 331

  Fly   369 --GLYSGSWLLARSYSG-DYLKHVQNFK----------------KIRWIYQVYLLMVRFMTEDLR 414
              ..|..|.:...:.:. |.|...|..|                ::|||.:      |.....|.
  Rat   332 LAEFYINSTIYGETKAELDQLPVAQKKKGSSAFREPVYVTSFCHQLRWIAR------RSFKNLLG 390

  Fly   415 NIRSGLIAFGFFMITAVTLSLMYSGIGGLTQRTVQDVGGSIFMLSNEMIFTFSYGVTYIFPAALP 479
            |.::.:......:|..:.:..:|.|:.. ....:|:..|..|.|:....|| |.....:|.....
  Rat   391 NPQASVAQLIVTVILGLIIGALYFGLKN-DPTGMQNRAGVFFFLTTNQCFT-SVSAVELFVVEKK 453

  Fly   480 IIRREVGEGTYSLSAYYVA-LVLSFVPVAFFKGYVFLSVIYASIYYTRGFLLYLSMGFLMSLSAV 543
            :...|...|.|.:|:|:.. ||...:|:.|..     ||||..       |||..:|...::.|.
  Rat   454 LFIHEYISGYYRVSSYFFGKLVSDLLPMRFLP-----SVIYTC-------LLYFMLGLKRTVEAF 506

  Fly   544 AAVGYGVFLSSLFESDKMASECAAPFDLI-------------FLIFGGTYMNVDTV-PGLKYLSL 594
            ..:.:.:.:.: :.:..||...||...::             .::|.|..:|:.|: |.|.:|..
  Rat   507 FIMMFTLIMVA-YTASSMALAIAAGQSVVSVATLLMTISFVFMMLFSGLLVNLRTIGPWLSWLQY 570

  Fly   595 F---------FYSNEALMYKFWIDIDNIDCP---VNEDHPCIK-----TGVEVLQQGSYRNADYT 642
            |         ...||.|..:|        ||   |..:..|:.     ||.:.|.......:.:.
  Rat   571 FSIPRYGFTALQHNEFLGQEF--------CPGLNVTMNSTCVNSYTICTGNDYLINQGIDLSPWG 627

  Fly   643 YWLDCFSLVVVAVIFHIVSF 662
            .|.:..:|..:.:||..:::
  Rat   628 LWRNHVALACMIIIFLTIAY 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	86/291 (30%)
		3a01204	40..673	CDD:273361	171/697 (25%)
		ABC2_membrane	404..604	CDD:279410	47/223 (21%)
Abcg2	NP_852046.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25		1/2 (50%)
		3a01204	46..651	CDD:273361	173/711 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820