Protein Alignment bw and Abcg4

DIOPT Version :9

• Sequence 1: NP_001286769.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_001100286.2
• Gene: Abcg4 / 300664
• RGDID: 1305840
• Length: 646
• Species: Rattus norvegicus
• Alignment Length: 682
• Identity: 157/682 - (23%)
• Similarity: 282/682 - (41%)
• Gaps: 132/682 - (19%)

  Fly    17 LEWKQLNYYVPDQEQSNYSFWNECRKKRELR-ILQDASGHMKTGDLIAILGGSGAGKTTLLAAIS 80
            :|:.:|:|.|.:         ..|.:||..: :|:..||.....:||.|:|.|||||:|.:..::
  Rat    61 IEFVELSYSVRE---------GPCWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILA 116

  Fly    81 QRLRGNLTGDVVLNGMAMERHQMTRISSFLPQFEINVKTFTAYEHLYFMSHFKMHRRTTKAEKRQ 145
            ......:.|.:::||...:.....::|.::.|.::.:...|..|.:...::.|:..:  :..|::
  Rat   117 GYRESGMKGQILVNGRPRDLRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEK--QEVKKE 179

  Fly   146 RVADLLLAVGLRDAAHTRIQQLSGGERKRLSLAEELITDPIFLFCDEPTTGLDSFSAYSVIKTLR 210
            .|.::|.|:||...:|||...||||:||||::|.||:.:|..:|.||||:||||.|.:.|:..::
  Rat   180 LVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 244

  Fly   211 HLCTRRRIAKHSLNQVYGEDSFETPSGESSASGSGSKSIEMEVVAESHESLLQTMRELPALGVLS 275
            .|                            |.|.
  Rat   245 SL----------------------------AHGG------------------------------- 250

  Fly   276 NSPNGTHKKAAICSIHQPTSDIFELFTHIILMDGGRIVYQGRTEQAAKFFTDLGYELPLNCNPAD 340
                    :..||:||||::.:||:|..:.::..|:.:::|.......:...||...|...||||
  Rat   251 --------RTVICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPAD 307

  Fly   341 FYLKTLADKEGKENAGAVLRAKYEHETDGLYSGSWLLARSYSGDYLKHV---------------Q 390
            |.::..:.:.|..|. .:.||        :.:|...:|...|......|               .
  Rat   308 FIIEVASGEYGDLNP-MLFRA--------VQNGLCTMAEKKSSPEKNEVPAHCPTCPPELDPIES 363

  Fly   391 NFKKIRWIYQVYLLMVRFMTEDLRNIRSGLIAFGFFMITAVTLSLMYSGIGGLTQRTVQDVGGSI 455
            :......:.|..:|..|.....||:.....:.|...::..|.:.|:|..||....:...:.|...
  Rat   364 HTFATSTLTQFCILFRRTFLSILRDTVLTHLRFMSHVLIGVLIGLLYLHIGDDASKVFNNTGFLF 428

  Fly   456 F-MLSNEMIFTFSYGVTYIFPAALPIIRREVGEGTYSLSAYYVALVLSFVPVAFFKGYVFLSVIY 519
            | ||.  ::|.........||..:.:..||.....|||.|||:|..::.||.     .|...|:|
  Rat   429 FSMLF--LMFAALMPTVLTFPLEMAVFMREHLNYWYSLKAYYLAKTMADVPF-----QVVCPVVY 486

  Fly   520 ASIYY--------TRGFLLYLSMGFLMSLSAVAAVGYGVFLSSLFESDKMASECAAPFDLIFLIF 576
            .||.|        |..|||:.::..   .:|:.|...|:.:.:...|.::|:.......:..|:|
  Rat   487 CSIVYWMTGQPAETSRFLLFSALSI---ATALVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLF 548

  Fly   577 GGTYMNVDTVPGL----KYLSLFFYSNEALMYKFW-IDIDNIDCPVNEDHPCIKTGVEVLQQGSY 636
            .|.:::..|:|..    .|||...|..|.|:...: ::..::.|  .|||...:....:|.:...
  Rat   549 SGFFVSFKTIPTYLQWSSYLSYVRYGFEGLILTIYGMERGHLTC--LEDHCPFRDPQIILHELDV 611

  Fly   637 RNADYTYWLDCFSLVVVAVIFHIVSFGLVRRY 668
            ..|  ..::|...|.:..:...:::: ||.||
  Rat   612 EEA--KLYMDFLVLGIFFLALRLLAY-LVLRY 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	69/285 (24%)
		3a01204	40..673	CDD:273361	153/659 (23%)
		ABC2_membrane	404..604	CDD:279410	54/212 (25%)
Abcg4	NP_001100286.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810