Protein Alignment bw and Abcg3l1

DIOPT Version :10

• Sequence 1: NP_523824.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_001004076.2
• Gene: Abcg3l1 / 289453
• RGDID: 1303294
• Length: 646
• Species: Rattus norvegicus
• Alignment Length: 734
• Identity: 157/734 - (21%)
• Similarity: 269/734 - (36%)
• Gaps: 248/734 - (33%)

  Fly    41 RKKRELRILQDASGHMKTGDLIAILGGSGAGKTTLLAAISQRLRG-NLTGDVVLNGMAMERHQMT 104
            ::.|.:..|...||.|..| |.||:|.....::.||..::.|... .|:||:::||.....: ..
  Rat    56 QQTRVMERLSSISGIMGPG-LNAIMGPQDGSRSLLLDVLAARRDPCGLSGDILINGKPRPAN-FK 118

  Fly   105 RISSFLPQFEINVKTFTAYEHLYFMSHFKMHRRTTKAEKRQRVADLLLAVGLRDAAHTRIQQLSG 169
            ..|.::||.::.:.|.|..::|.|.:..::....|:.|||:|:.::|..:.|.  ....::..|.
  Rat   119 CTSGYIPQNDVVLGTVTVRDNLEFSAALRLPMTVTRDEKRRRINEVLELLHLE--KEQNVKPRSK 181

  Fly   170 GERKRLSLAEELITDPIFLFCDEPTTGLDSFSAYSVIKTLRHLCTRRRIAKHSLNQVYGEDSFET 234
            |.|||.|:|.||:|:...||.|:||||||..:...||..||.:
  Rat   182 GLRKRTSIAMELVTEHPILFLDDPTTGLDLRTTTDVISILRRM---------------------- 224

  Fly   235 PSGESSASGSGSKSIEMEVVAESHESLLQTMRELPALGVLSNSPNGTHKKAAICSIHQPTSDIFE 299
                 |..|                                        |..|.||:||...||.
  Rat   225 -----SMKG----------------------------------------KTIIFSINQPQYSIFR 244

  Fly   300 LFTHIILMDGGRIVYQGRTEQAAKFFTDLGYELPLNCNPADFYLKTL------ADKEG---KENA 355
            .|..:.|:..|::::.|....|.::||..||:...:.|||||:|..:      .:::|   .||.
  Rat   245 FFDSLTLVASGKLMFHGPARDALEYFTSAGYQYESHNNPADFFLDVINGGFPDTEEDGHEADENE 309

  Fly   356 GAVLRAKYEHETDG----LYSGS--------------------------------------WLLA 378
            ..|.|   :|:..|    :|:.|                                      |:..
  Rat   310 EFVER---QHQVTGKLANMYAQSPLHSATRARLDQLLGEQKLDRSSAVETTCVTPFWHQLGWITR 371

  Fly   379 RSYSGDYLKHVQNFKKIRWIYQVYLLMVRFMT-------EDLRNI------RSGLIAF--GFFMI 428
            ||:        :||....|:..:.::::..:.       ..|:|:      |:.||..  ||..|
  Rat   372 RSF--------KNFLGFPWVTTIQVIIIVILAVVVGTAFRLLQNVCTELQMRAILILLLTGFQCI 428

  Fly   429 TAVTLSLMYSGIGGLTQRTVQDVGGSIFMLSNEMIFTFSYGVTYIFPAALPIIRREVGEGTYSLS 493
            |:||                   .|.:|::..:...                  .|...|.|.:|
  Rat   429 TSVT-------------------AGELFVIDQDRFL------------------HEHTSGYYRVS 456

  Fly   494 AYYVA-LVLSFVPVAFFKGYVFLSVIY------ASI--YYTRGF----LLYLSMGFLMSLSA--- 542
            :|:.. |:...:|.......:|..:.|      .|:  ::|..|    |.|.:....:||.|
  Rat   457 SYFFGKLLAELIPRRLLPSTIFTLITYFIAGLRTSVRGFFTMTFTIMMLAYSASSLSLSLGAGEN 521

  Fly   543 VAAVG------YGVFLSSLFESDKMASECAAPFDLIFLIFGGTYMNVDTVPGL---KYLSLFFYS 598
            |||:.      |.||:                     |.|.|..::...:|.|   :|.|:..|.
  Rat   522 VAAITTLLVTIYFVFM---------------------LFFSGLSLDTGFLPVLSWIRYFSIPHYG 565

  Fly   599 NEALMYKFWIDIDNIDCP---VNEDHPC----IKTGVEVLQQGSYRNADYTYW-----LDCFSLV 651
            ..||::..::. .|. ||   ..|...|    |.||.|.|:...:..:.:.:|     |.|..::
  Rat   566 FRALLHNEFLG-QNF-CPEYNTEEVSRCQNYVICTGEEFLEIQGFHLSSWGFWENHLALACTMII 628

  Fly   652 VVAVIFHIVSFGLVRRYIH 670
            ::.:.:  |...|:::..|
  Rat   629 LLTITY--VQLLLLKKRKH 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_523824.1	3a01204	40..673	CDD:273361	157/734 (21%)
Abcg3l1	NP_001004076.2	3a01204	64..644	CDD:273361	155/723 (21%)