Protein Alignment bw and Abcg3

DIOPT Version :10

• Sequence 1: NP_523824.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: XP_017176394.1
• Gene: Abcg3 / 27405
• MGIID: 1351624
• Length: 683
• Species: Mus musculus
• Alignment Length: 728
• Identity: 150/728 - (20%)
• Similarity: 262/728 - (35%)
• Gaps: 234/728 - (32%)

  Fly     3 ESGGSSGQGGPSLCLEWKQ----------------LNYYVPDQEQSN------------YSFWN- 38
            :|..:|....|.:..:||:                :..::.|..::|            .||.|
Mouse    51 KSSCASSNLSPCIISQWKKEPPEMASNNDPTVISMIERHLCDLPETNTSDLKTLTEEAVLSFHNI 115

  Fly    39 ----------ECRKKR-ELRILQDASGHMKTGDLIAILGGSGAGKTTLLAAISQRL--RGNLTGD 90
                      ..|||. .:..|.:.||.||.| |.||:|.....::.||..::.|.  || |:||
Mouse   116 SYQETVQSGFPLRKKAYVIERLSNISGIMKPG-LNAIMGPQDGSRSLLLDVLAARRDPRG-LSGD 178

  Fly    91 VVLNGMAMERHQMTRISSFLPQFEINVKTFTAYEHLYFMSHFKMHRRTTKAEKRQRVADLLLAVG 155
            :::||.....: ....|.::||.::.:.|.|..::|.|.:..::....|:.|||:|:.::|..:.
Mouse   179 ILINGKPRPAN-FKCTSGYVPQNDVVLGTVTVRDNLEFSAALRLPVTITRDEKRRRINEVLELLH 242

  Fly   156 LRDAAHTRIQQLSGGERKRLSLAEELITDPIFLFCDEPTTGLDSFSAYSVIKTLRHLCTRRRIAK 220
            |.  ....|:..|...|||.|:|.||:|:...||.|:||||||..:...||..||.:..:.|
Mouse   243 LN--KEQNIKPRSKELRKRTSIAMELVTEHPILFLDDPTTGLDLRTTTDVILVLRRMSKKGR--- 302

  Fly   221 HSLNQVYGEDSFETPSGESSASGSGSKSIEMEVVAESHESLLQTMRELPALGVLSNSPNGTHKKA 285
                                                                            .
Mouse   303 ----------------------------------------------------------------T 303

  Fly   286 AICSIHQPTSDIFELFTHIILMDGGRIVYQGRTEQAAKFFTDLGYELPLNCNPADFYLKTL---- 346
            .|.||:||...||:.|..:.|:..|::::.|..:.|.::|...||....:.|||||:|..:
Mouse   304 IIFSINQPQYSIFKFFDSLTLVASGKVMFHGPAQDALEYFRSAGYNYESHNNPADFFLDVINGGF 368

  Fly   347 -----ADKEGKENAGAVLRAKYEHETDGLYSGSWLLARSYSG-----------DYLKHVQNFKK- 394
                 .:::|.|:      .|||...:..|..:..||..|:.           |.|...|..::
Mouse   369 SNILDTEEDGHED------DKYEELFERQYQVTGKLANMYAQSPLYSETRAILDQLLGEQKLERS 427

  Fly   395 --------------IRWIYQVYLLMVRFMTEDLRNIRSGLIAFGFFMITAVTLSLMYSGIGGLTQ 445
                          ::||          :.:..:|.:      ||..:|.:...        :|.
Mouse   428 SAVETTCVTPFCHQLKWI----------ICQSFKNFK------GFPWVTVIQAI--------ITV 468

  Fly   446 RTVQDVGGSIFMLSNEMI-----------FTFSYGVTYIFPAALPIIRR-----EVGEGTYSLSA 494
            .....||.:..:|.|:.|           .|....:|.:....|.:|.|     |...|.|.:|:
Mouse   469 ILATAVGTAFRVLKNDCIEVQMRAGLLYLLTIFQCITSVSAGELFVIDRVRFLHEHTSGYYRVSS 533

  Fly   495 YYVA-LVLSFVPVAFFKGYVFLSVIYA------------SIYYTRGFLLYLSMGFLMSLSA-VAA 545
            |:.. |:...:|.......||..:.|.            ::..|...|.|.:....:|:.| ..|
Mouse   534 YFFGKLLAELIPRRLLPSTVFSLITYVIAGVKMSMKCFFTMICTIMVLAYSASSLPLSIGAGENA 598

  Fly   546 VGYGVFLSSLFESDKMASECAAPFDLIFLIF-------GGTYMNVDTVPGLKYLSLFFYSNEALM 603
            |.....|.:::              .:|::|       .|:::  ..:..::|.|:..|...||:
Mouse   599 VAVPTLLVTIY--------------FVFMLFFSGLSLYSGSFL--PKLSWIQYFSIPHYGFRALL 647

  Fly   604 YKFWIDIDNIDCP 616
            :..::. .|. ||
Mouse   648 HNEFLG-QNF-CP 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_523824.1	3a01204	40..673	CDD:273361	140/652 (21%)
Abcg3	XP_017176394.1	3a01204	137..670	CDD:273361	137/642 (21%)