Protein Alignment bw and Abcg4

DIOPT Version :9

• Sequence 1: NP_001286769.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_620405.3
• Gene: Abcg4 / 192663
• MGIID: 1890594
• Length: 646
• Species: Mus musculus
• Alignment Length: 698
• Identity: 158/698 - (22%)
• Similarity: 286/698 - (40%)
• Gaps: 164/698 - (23%)

  Fly    17 LEWKQLNYYVPDQEQSNYSFWNECRKKRELR-ILQDASGHMKTGDLIAILGGSGAGKTTLLAAIS 80
            :|:.:|:|.|.:         ..|.:||..: :|:..||.....:||.|:|.|||||:|.:..::
Mouse    61 IEFVELSYSVRE---------GPCWRKRGYKTLLKCLSGKFCRRELIGIMGPSGAGKSTFMNILA 116

  Fly    81 QRLRGNLTGDVVLNGMAMERHQMTRISSFLPQFEINVKTFTAYEHLYFMSHFKMHRRTTKAEKRQ 145
            ......:.|.:::||...|.....::|.::.|.::.:...|..|.:...::.|:..:  :..|::
Mouse   117 GYRESGMKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSANLKLSEK--QEVKKE 179

  Fly   146 RVADLLLAVGLRDAAHTRIQQLSGGERKRLSLAEELITDPIFLFCDEPTTGLDSFSAYSVIKTLR 210
            .|.::|.|:||...:|||...||||:||||::|.||:.:|..:|.||||:||||.|.:.|:..::
Mouse   180 LVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 244

  Fly   211 HLCTRRRIAKHSLNQVYGEDSFETPSGESSASGSGSKSIEMEVVAESHESLLQTMRELPALGVLS 275
            .|                            |.|.
Mouse   245 SL----------------------------AHGG------------------------------- 250

  Fly   276 NSPNGTHKKAAICSIHQPTSDIFELFTHIILMDGGRIVYQGRTEQAAKFFTDLGYELPLNCNPAD 340
                    :..||:||||::.:||:|..:.::..|:.:::|.......:...||...|...||||
Mouse   251 --------RTVICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKGLGLHCPTYHNPAD 307

  Fly   341 FYLK----------------------TLADKE---GKENAGAVLRAKYEH------ETDGLYSGS 374
            |.::                      |:|:|:   ||....|       |      |.|.:.|.:
Mouse   308 FIIEVASGEYGDLNPMLFRAVQNGLCTMAEKKSSPGKNELPA-------HCPTCPPELDPIESHT 365

  Fly   375 WLLARSYSGDYLKHVQNFKKIRWIYQVYLLMVRFMTEDLRNIRSGLIAFGFFMITAVTLSLMYSG 439
            :..:.                  :.|..:|..|.....||:.....:.|...::..|.:.|:|..
Mouse   366 FATST------------------LTQFCILFRRTFLSILRDTVLTHLRFMSHVLIGVLIGLLYLH 412

  Fly   440 IGGLTQRTVQDVGGSIF-MLSNEMIFTFSYGVTYIFPAALPIIRREVGEGTYSLSAYYVALVLSF 503
            ||....:...:.|...| ||.  ::|.........||..:.:..||.....|:|.|||:|..::.
Mouse   413 IGDDASKVFNNTGFLFFSMLF--LMFAALMPTVLTFPLEMAVFMREHLNYWYTLKAYYLAKTMAD 475

  Fly   504 VPVAFFKGYVFLSVIYASIYY--------TRGFLLYLSMGFLMSLSAVAAVGYGVFLSSLFESDK 560
            ||.     .|...|:|.||.|        |..|||:.::..   .:|:.|...|:.:.:...|.:
Mouse   476 VPF-----QVVCPVVYCSIVYWMTGQPAETSRFLLFSALAI---ATALVAQSLGLLIGAASTSLQ 532

  Fly   561 MASECAAPFDLIFLIFGGTYMNVDTVPGL----KYLSLFFYSNEALMYKFW-IDIDNIDCPVNED 620
            :|:.......:..|:|.|.:::..|:|..    .|||...|..|.|:...: ::..::.| ::|.
Mouse   533 VATFVGPVTAIPVLLFSGFFVSFKTIPTYLQWSSYLSYVRYGFEGLILTIYGMERGHLTC-LDEQ 596

  Fly   621 HPCIKTGVEVLQQGSYRNADYTYWLDCFSLVVVAVIFHIVSFGLVRRY 668
            .| .:....:|::.....|  ..::|...|.:..:...:::: ||.||
Mouse   597 CP-FRDPQIILRELDVEEA--KLYMDFLVLGIFFLALRLLAY-LVLRY 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	70/285 (25%)
		3a01204	40..673	CDD:273361	154/675 (23%)
		ABC2_membrane	404..604	CDD:279410	53/212 (25%)
Abcg4	NP_620405.3	3a01204	44..646	CDD:273361	158/698 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810