Protein Alignment bw and wht-8

DIOPT Version :9

• Sequence 1: NP_001286769.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_499442.2
• Gene: wht-8 / 189976
• WormBaseID: WBGene00012925
• Length: 619
• Species: Caenorhabditis elegans
• Alignment Length: 692
• Identity: 190/692 - (27%)
• Similarity: 322/692 - (46%)
• Gaps: 148/692 - (21%)

  Fly    17 LEWKQLNYYVPDQEQSNYSFWNECRKKRELRILQDASGHMKTGDLIAILGGSGAGKTTLLAAISQ 81
            |:|:.|                :...|....:|...||....|::||::|.|||||||||..:.|
 Worm    34 LQWRNL----------------KVTTKAGRVLLNGVSGCAVPGEVIALMGASGAGKTTLLNTLLQ 82

  Fly    82 R-LRG-NLTGDVVLNGMAMERHQMTRISSFLPQFEINVKTFTAYEHLYFMSHFKMHRRTTKAEKR 144
            | ||| .:.|::::||..:.: .:|.:|:::.|.::.:.|.|..|||...:..::...|:...:.
 Worm    83 RNLRGLQVEGEILVNGQNIGK-GVTSVSAYVQQEDLFMGTLTVKEHLDIQAKLRLPPGTSTTARA 146

  Fly   145 QRVADLLLAVGLRDAAHTRI------QQLSGGERKRLSLAEELITDPIFLFCDEPTTGLDSFSAY 203
            .||.:::..:.|.....:||      :.:||||.|||:.|.|:|.:|..:|||||||||||..:.
 Worm   147 TRVNEVMNEMLLEKPRDSRIGVPGIKKGISGGEMKRLAFATEMINNPPIIFCDEPTTGLDSHMSL 211

  Fly   204 SVIKTLRHLCTRRRIAKHSLNQVYGEDSFETPSGESSASGSGSKSIEMEVVAESHESLLQTMREL 268
            .|:|||..:...:
 Worm   212 QVVKTLEQMALEK---------------------------------------------------- 224

  Fly   269 PALGVLSNSPNGTHKKAAICSIHQPTSDIFELFTHIILMDGGRIVYQGRTEQAAKFFTDLGYELP 333
                          .|..||:||||:|::||:|..::.:..|||.:.|..::|...|:..||::|
 Worm   225 --------------GKTIICTIHQPSSEVFEIFDKVVFLAQGRIAFHGAIDEAIHHFSSCGYQVP 275

  Fly   334 LNCNPADFYLKTLADKEGKENAGAVLRAKYEHETDGLYSGSWLLARSYSGDYL-KHVQNFKKIRW 397
            .:.||||:::.|||.|..:..|   .:::.:...|       ...:|:..:.| |.:...|.:|.
 Worm   276 DHTNPADYFIDTLAIKPSEAEA---CKSRCQELCD-------KFEKSFYNERLTKLMDQTKDVRA 330

  Fly   398 I-------YQV--YLLMVRFMTEDLRN---IRSGLIA---FGFFMITAVTLSLMYSGIGGLTQRT 447
            :       |.|  |.|..|:|.:::||   :::.||.   .|.|:.|     |.|    ||  .|
 Worm   331 MTPHHSATYPVLLYALFYRYMLDNIRNPAIMKAKLIQKLFMGLFIGT-----LFY----GL--ET 384

  Fly   448 VQD----VGGSIFMLSNEMIFTFSYGVTYIFPAALPIIRREVGEGTYSLSAYYVALVLSFVPVAF 508
            .||    ..|::|...:|:.::..:|:....||..|.:.||..:..|.:||||:|.:.||:|:..
 Worm   385 DQDGLASYKGALFYYISELTYSTIFGIQAFMPADYPPLVREYDDRIYPISAYYIAKICSFLPIFT 449

  Fly   509 FKGYVFLSVIYASIYYTRGFLLYLSMGF-LMSLS-AVAAVGYGVFLSSLFESDKMASECAAPFDL 571
            ..|.:.:...|..:.:...|.::|...| .|::. .|||:|..|..::  .|..:|.....|...
 Worm   450 VDGIILVVSSYFLVGFPSDFGVFLRQIFTCMAIEWNVAALGIAVCATA--PSYAIAVTVTGPLLT 512

  Fly   572 IFLIFGGTYMNVDTVPG----LKYLSLFFYSNEALMY-KFWID-IDNIDCPVN-EDHPCIKTGVE 629
            :|.:.||.:.|:..:|.    ::|||.|.|..|:|:. :|..| ..||.|..| .:..|.|:|..
 Worm   513 VFSLTGGLFTNIAEMPAWINWVQYLSWFRYGYESLVVNQFQHDQFANITCNANMNEQLCEKSGPI 577

  Fly   630 VLQQGSYRNAD-YTYWLDCFSLVVVAVIFHIVSF-GLVRRYI 669
            .::..|:..|: ||.|:   :::.:.:|.:||.: |||||.|
 Worm   578 AIKNFSFDTANLYTNWV---AMIYLTIIIYIVGYMGLVRRVI 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	79/292 (27%)
		3a01204	40..673	CDD:273361	187/669 (28%)
		ABC2_membrane	404..604	CDD:279410	61/215 (28%)
wht-8	NP_499442.2	3a01204	22..615	CDD:273361	188/689 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.780