Protein Alignment bw and wht-2

DIOPT Version :9

• Sequence 1: NP_001286769.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_502164.1
• Gene: wht-2 / 178069
• WormBaseID: WBGene00007513
• Length: 610
• Species: Caenorhabditis elegans
• Alignment Length: 657
• Identity: 192/657 - (29%)
• Similarity: 307/657 - (46%)
• Gaps: 126/657 - (19%)

  Fly    42 KKRELRILQDASGHMKTGDLIAILGGSGAGKTTLL-AAISQRLRG-NLTGDVVLNGMAMERHQMT 104
            :|...:||::.||..|.|.|:|::|.||||||||| ..:|:.||| ..:|.|.:||..:.| .:|
 Worm    44 EKSGKQILENVSGIAKPGQLLALMGASGAGKTTLLNMLLSRNLRGLETSGSVKVNGHELGR-GIT 107

  Fly   105 RISSFLPQFEINVKTFTAYEHLYFMSHFKMHRRTTKAEKRQRVADLLLAVGLRDAAHTRI----- 164
            .||.:..|.|:.|.|.|..|:|...:..:::..:.|  :|:||.:::..:||....:|||
 Worm   108 AISGYAQQDELFVGTLTVKEYLDIQAKLRVNGDSEK--RRRRVGNVMSQLGLYKCQNTRIGTIGG 170

  Fly   165 -QQLSGGERKRLSLAEELITDPIFLFCDEPTTGLDSFSAYSVIKTLRHLCTRRRIAKHSLNQVYG 228
             :.:||||.:||:.|.||:::|..|||||||||||||.|.||::.|.:|
 Worm   171 QKGISGGEMRRLTFACELLSNPSILFCDEPTTGLDSFMAESVVQVLSNL---------------- 219

  Fly   229 EDSFETPSGESSASGSGSKSIEMEVVAESHESLLQTMRELPALGVLSNSPNGTHKKAAICSIHQP 293
                       :.||                                        :..||:||||
 Worm   220 -----------AKSG----------------------------------------RTVICTIHQP 233

  Fly   294 TSDIFELFTHIILMDGGRIVYQGRTEQAAKFFTDLGYELPLNCNPADFYLKTLADKEGKENAG-- 356
            :|.::.:|..::.|.||:..:.|....|.:||.|.|:..|.|.||||..:.|||....:|:..
 Worm   234 SSQLYLMFDRVMFMAGGKTAFLGSPRDAIQFFEDAGFACPRNFNPADLIIHTLAVMPNEEDKCRQ 298

  Fly   357 --AVLRAKYEHETDG--LYSGSWLLARSYSGDYLKHVQNFKKIRWIYQVYLLMVRFMTEDLRN-- 415
              .|:..|:::.:.|  |..|   :.:|..|   :......|...:.|:..|:.|...:..||
 Worm   299 RIEVIYTKFQNSSYGRTLKFG---VEKSDEG---QRPSERHKTGILTQIGALLERSAIDTWRNPS 357

  Fly   416 -IRSGLI---AFGFFMITAVTLSLMYSGIGGLTQRTVQDVGGSIFMLSNEMIFTFSYGVTYIFPA 476
             .|:.:|   ..|.|      :.|:|.. ..||...:.::.|::|.|..|:.::..:|:....||
 Worm   358 LTRAKVIQKSIMGLF------IGLLYLQ-SPLTSIGISNLNGALFYLVCELTYSTIFGILNFLPA 415

  Fly   477 ALPIIRREVGEGTYSLSAYYVALVLSFVPVAFFKGYVFLSVIYASIYYTRGF--LLYLSM-GFLM 538
            ..|::.||..:|.||:.:||||..||::|:....|.:.|.|.|..:.::...  :||..: .||:
 Worm   416 DFPLVSREYHDGLYSVFSYYVARCLSYLPLFTADGLIMLLVSYWMVGFSSSITQVLYACLIAFLI 480

  Fly   539 SLSAVAAVGYGVFLSSLFESDKMASECAAPFDLIFLIFGGTYMNVDTVPG----LKYLSLFFYSN 599
            ..|:.|.   |:.:|.:..|..:|...|.|...:..:.||.|.||..:|.    ::|||.|.|..
 Worm   481 EQSSSAC---GIMISCISPSLPIAMSTAGPMLTLLSLTGGLYANVGALPSYISWIQYLSWFRYGF 542

  Fly   600 EALMYKFWIDIDNIDCPVNEDHPCIKTGVE---VLQQGSYRNADYTYWLDCFSLVVVAVIFHIVS 661
            ||.....|       ..|||.:..|.|..:   ||.|.|:|..  .::.|.|.:....:||:.:.
 Worm   543 EAFAINQW-------SSVNEQNTTIWTDEKRDSVLSQLSFRAE--MFYPDLFIMSAFILIFYTIG 598

  Fly   662 F-GLVRR 667
            : ||..|
 Worm   599 YAGLALR 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	88/281 (31%)
		3a01204	40..673	CDD:273361	192/657 (29%)
		ABC2_membrane	404..604	CDD:279410	61/212 (29%)
wht-2	NP_502164.1	3a01204	44..610	CDD:273361	192/657 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820