Protein Alignment bw and wht-3

DIOPT Version :9

• Sequence 1: NP_001286769.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_497825.2
• Gene: wht-3 / 175528
• WormBaseID: WBGene00007631
• Length: 614
• Species: Caenorhabditis elegans
• Alignment Length: 664
• Identity: 162/664 - (24%)
• Similarity: 282/664 - (42%)
• Gaps: 159/664 - (23%)

  Fly    43 KRELRILQDASGHMKTGDLIAILGGSGAGKTTLLAAISQR-LRG-NLTGDVVLNGMAMERHQMTR 105
            |::.::|...||..|.|:::|::|.||||||||:..:..| ::| ...|.|.:||..:.: :::.
 Worm    55 KKQKQLLNRVSGIAKPGEMVALMGASGAGKTTLMNVLMCRNMKGLEKNGTVKVNGTKIGK-EISL 118

  Fly   106 ISSFLPQFEINVKTFTAYEHLYFMSHFKMHRRTTKAEKRQRVADLLLAVGLRDAAHTRI------ 164
            ||.|..|.||.:.|.|..|:|...:..:|  :..|..:|:||.:::..:.|::....:|
 Worm   119 ISGFAQQQEIFIPTLTVDEYLMIQARLRM--KANKHTRRERVDEIIEMLRLQNCRDLKIGTPGLV 181

  Fly   165 QQLSGGERKRLSLAEELITDPIFLFCDEPTTGLDSFSAYSVIKTLRHLCTRRRIAKHSLNQVYGE 229
            :.:||||.:||:.|.||:::|..||.||||:|||||.|.||::.|::|
 Worm   182 KGISGGEARRLTFACELLSNPSLLFADEPTSGLDSFMAASVVQILKNL----------------- 229

  Fly   230 DSFETPSGESSASGSGSKSIEMEVVAESHESLLQTMRELPALGVLSNSPNGTHKKAAICSIHQPT 294
                                     |.|..:|                            |||||
 Worm   230 -------------------------ANSGRTL----------------------------IHQPT 241

  Fly   295 SDIFELFTHIILMDGGRIVYQGRTEQAAKFFTDLGYELPLNCNPADFYLKTLA-----DKEGKEN 354
            :::|..|..||.:..|:..:.|...::.|||.|.|:.:|...||.::....|:     :.:.:|.
 Worm   242 AELFFQFDKIIFLSMGKTAFMGTPHESVKFFADCGHPIPKLFNPPEWIQSKLSVIPNNETKSRET 306

  Fly   355 AGAVLRAKYEHETDGLYSGSWLLARSYSGDYLKHVQNFKKIRWIYQVYL---------------L 404
            .|.::.         .|..|           :.|.::..:||.|....|               |
 Worm   307 IGKIIE---------FYEKS-----------IIHQKSIVEIRVIATTELPPYIENPGFFAETGAL 351

  Fly   405 MVRFMTEDLRN---IRSGLI---AFGFFMITAVTLSLMYSGIGG------LTQRTVQDVGGSIFM 457
            :.|...:.:|:   :|..||   ..|.|             ||.      |..|.|::...:::.
 Worm   352 LKRACLDVIRSPAQMRMKLIQKVVMGLF-------------IGSLYWQQPLDPRGVRNTNSALYF 403

  Fly   458 LSNEMIFTFSYGVTYIFPAALPIIRREVGEGTYSLSAYYVALVLSFVPVAFFKGYVFLSVIYASI 522
            |..|:.|:..:|:.......||:|.||..:|.:.:.:||::..||::|:....|.:.:.:.|..|
 Worm   404 LIAELTFSTMFGIMTFMEHELPLIAREYHDGLFYVISYYISRFLSYLPLFTIDGALMIVISYWMI 468

  Fly   523 YYTRGFLLYLSMGFLMSLSAVAAVGYGVFLSSLFESDKMASECAAPFDLIFLIFGGTYMNVDTVP 587
            .....:........:..|...:|...|:||:.|||:..:|...|.|...:|.:..|.|.|.:..|
 Worm   469 GLNSTWQQVAKSILISVLVEQSATSCGLFLACLFETTSLAIAFAVPASGLFALLSGLYGNTNNFP 533

  Fly   588 ----GLKYLSLFFYSNEALMYKFWIDIDNIDCPVNEDHPCIKTGVEVLQQGSYRNADYTYWLDCF 648
                .:::.|...|..|.|:...|..:||     .:..|..:.  .:|:|.|: |.| .|.||..
 Worm   534 VYIRWMQWTSWCRYGFEGLVVNQWSQVDN-----PKWDPFYRE--LILKQFSF-NKD-NYQLDVI 589

  Fly   649 SLVVVAVIFHIVSF 662
            .|..:.:.|::..:
 Worm   590 GLCSIVIFFYLAGY 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	78/280 (28%)
		3a01204	40..673	CDD:273361	162/664 (24%)
		ABC2_membrane	404..604	CDD:279410	51/215 (24%)
wht-3	NP_497825.2	ABCG_EPDR	36..263	CDD:213180	78/280 (28%)
		3a01204	37..614	CDD:273361	162/664 (24%)
		ABC2_membrane	351..555	CDD:279410	51/216 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.780