Protein Alignment bw and Abcg8

DIOPT Version :9

• Sequence 1: NP_001286769.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_569098.2
• Gene: Abcg8 / 155192
• RGDID: 620300
• Length: 672
• Species: Rattus norvegicus
• Alignment Length: 648
• Identity: 145/648 - (22%)
• Similarity: 256/648 - (39%)
• Gaps: 180/648 - (27%)

  Fly    12 GPSLCLEWKQLNYYV-----------------PDQEQSNYSFWNECRKKRELRILQDASGHMKTG 59
            |.|..||.:.|.|.|                 |.:.:.:...|       :|.| ::.|..:::|
  Rat    42 GQSNTLEVRDLTYQVDMASQVPWFEQLAQFKLPWRSRGSQDSW-------DLGI-RNLSFKVRSG 98

  Fly    60 DLIAILGGSGAGKTTLLAAISQRLRGN--LTGDVVLNGMAMERHQMTRISSFLPQFEINVKTFTA 122
            .::||:|.:|.|:.|||..|:.|..|.  .:|.:.:||.......:.:..:.:.|.:..:...|.
  Rat    99 QMLAIIGSAGCGRATLLDVITGRDHGGKMKSGQIWINGQPSTPQLIQKCVAHVRQQDQLLPNLTV 163

  Fly   123 YEHLYFMSHFKMHRRTTKAEKRQRVADLLLAVGLRDAAHTR-----IQQLSGGERKRLSLAEELI 182
            .|.|.|::..::.:..::|::.:||.|::..:.||..|:||     ::.:|||||:|:|:..:|:
  Rat   164 RETLTFIAQMRLPKTFSQAQRDKRVEDVIAELRLRQCANTRVGNTYVRGVSGGERRRVSIGVQLL 228

  Fly   183 TDPIFLFCDEPTTGLDSFSAYSVIKTLRHLCTRRRIAKHSLNQVYGEDSFETPSGESSASGSGSK 247
            .:|..|..||||:|||||:|:::::||..|....|:
  Rat   229 WNPGILILDEPTSGLDSFTAHNLVRTLSRLAKGNRL----------------------------- 264

  Fly   248 SIEMEVVAESHESLLQTMRELPALGVLSNSPNGTHKKAAICSIHQPTSDIFELFTHIILMDGGRI 312
                                                  .:.|:|||.||||.||..::||..|..
  Rat   265 --------------------------------------VLISLHQPRSDIFRLFDLVLLMTSGTP 291

  Fly   313 VYQGRTEQAAKFFTDLGYELPLNCNPADFYLK-TLADKEGKENAGAVLRAKYEHETDGLYSGSWL 376
            :|.|..:...::||.:||..|...||||||:. |..|:..||...|.:..
  Rat   292 IYLGVAQHMVQYFTSIGYPCPRYSNPADFYVDLTSIDRRSKEQEVATMEK--------------- 341

  Fly   377 LARSYSGDYLKHVQNFKKIRW---------------------------------IYQVYLLMVRF 408
             ||..:..:|:.||.|....|                                 |.|...|:.|.
  Rat   342 -ARLLAALFLEKVQGFDDFLWKAEAKSLDTGTYAVSQTLTQDTNCGTAAELPGMIQQFTTLIRRQ 405

  Fly   409 MTEDLRNIRSGLIAFGFFMITAVTLSLMYSGIGGLTQRTVQDVGGSIFMLSNEMIFTFSYGVTYI 473
            ::.|.|::.:..|......:.::.:..:|.|... ...:..|:...:||:...:.|.....|...
  Rat   406 ISNDFRDLPTLFIHGAEACLMSLIIGFLYYGHAD-KPLSFMDMAALLFMIGALIPFNVILDVVSK 469

  Fly   474 FPAALPIIRREVGEGTYSLSAYYVALVLSFVPVAFFKGYVFLSVIYA-SIYYTRG-------FLL 530
            ..:...::..|:.:|.|:...|:.|.||..:|.  ...||   :||. .||:...       |||
  Rat   470 CHSERSLLYYELEDGLYTAGPYFFAKVLGELPE--HCAYV---IIYGMPIYWLTNLRPGPELFLL 529

  Fly   531 YLSMGFL-------MSLSAVAAVGYGVFLSSLFESDKMASECAAPFDLIFLIFGGTYMNVDTV 586
            :..:.:|       |:|:|          |::..:..|:|.|.......|.:..|..:|::.:
  Rat   530 HFMLLWLVVFCCRTMALAA----------SAMLPTFHMSSFCCNALYNSFYLTAGFMINLNNL 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	71/291 (24%)
		3a01204	40..673	CDD:273361	136/603 (23%)
		ABC2_membrane	404..604	CDD:279410	40/198 (20%)
Abcg8	NP_569098.2	ABCG_White	60..295	CDD:213201	72/309 (23%)
		3a01204	88..662	CDD:273361	135/595 (23%)
		ABC2_membrane	401..605	CDD:279410	40/198 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920