Protein Alignment bw and AgaP_AGAP008945

DIOPT Version :9

• Sequence 1: NP_001286769.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: XP_319700.4
• Gene: AgaP_AGAP008945 / 1279915
• VectorBaseID: AGAP008945
• Length: 646
• Species: Anopheles gambiae
• Alignment Length: 673
• Identity: 157/673 - (23%)
• Similarity: 255/673 - (37%)
• Gaps: 194/673 - (28%)

  Fly    48 ILQDASGHMKTGDLIAILGGSGAGKTTLLAAISQRLRGNLTGDVVLNGMAMERHQMTRISSFLPQ 112
            ||::.||..::|.|:.|:|.|||||:|||..:|...:.|:||.::::|..:...:..:|.|:..|
Mosquito    12 ILKNLSGSFRSGRLVGIMGPSGAGKSTLLNVLSGFKKSNVTGQLMVDGQRLSERRSRKIISYTQQ 76

  Fly   113 FEINVKTFTAYEHLYFMSHFKMHRRTTKAEKRQRVADLLLAVGLRDAAHTRIQQLSGGERKRLSL 177
            ........|..|.|.:.:.||:.....:.:||.||.:||..:||...|.|....:|||:.||||:
Mosquito    77 EVCLWPALTVEESLRYAAEFKLSPTIDQHQKRARVRELLHVLGLTGCADTLAGSVSGGQAKRLSI 141

  Fly   178 AEELITDPIFLFCDEPTTGLDSFSAYSVIKTLRHLCTRRRIAKHSLNQVYGEDSFETPSGESSAS 242
            ..||::||..:..||||:|||:.:||.|:..::.|..|.|:
Mosquito   142 GLELLSDPKVMLLDEPTSGLDTVAAYQVLAHVKQLAARGRV------------------------ 182

  Fly   243 GSGSKSIEMEVVAESHESLLQTMRELPALGVLSNSPNGTHKKAAICSIHQPTSDIFELFTHIILM 307
                                                       .:|.||||.|....|...:.::
Mosquito   183 -------------------------------------------IVCVIHQPNSQQLLLIDDLYVL 204

  Fly   308 DGGRIVYQGRTEQAAKFFTDLGYELPLNCNPADFYLKTLADKEGKENAGAVLR----------AK 362
            ..||.:|.|.|.:....|...|.:.|::.||||:      .|....||..:|.          |.
Mosquito   205 AKGRRIYSGPTGEMVTQFARFGLDCPVSHNPADY------GKNCAANAHIILAFSSLSAALEVAS 263

  Fly   363 YEHETDGL-------------YSGSWLLA-RSYSGDYLKH-VQNFKKIRWI-------------Y 399
            .:.|.|.|             |:...|:. :|..|.|.:: :...:::|.:             :
Mosquito   264 LDQEDDRLKRLMMEEEKDIFDYNPPRLMVEKSVDGSYQRYALSTLQQLRVLLRRTTSCTMRETSF 328

  Fly   400 QVYLLMVRFMT--EDLRNIRSGLIAFG----FF-------------------MIT---------- 429
            ||....:.|.|  |.||.:....|.||    :|                   |||
Mosquito   329 QVNGFRIIFNTIFEILRCVEHEHIKFGNEVRYFVVLVISSIFLLLFLNLSVIMITSPFPSSFQYQ 393

  Fly   430 -----------AVTLSLMYSGIGGLTQRTVQDVGGSIFMLSNEMIFTFSYGVTYIFPAALPIIRR 483
                       |:..|:.:...|....|.:.:....|..| ..:.||.......::|........
Mosquito   394 FKARILINIAIAIITSVAFYNTGNNADRILANTAVLIINL-YAIFFTSIVSAVLVYPRESACFVL 457

  Fly   484 EVGEGTYSLSAYYVALVLSFVPVAFFKGYVFLSVIYASIYYT-RGF---------LLYLSMGFL- 537
            |.....|||.|||:|.::..:|.......||..::|   |:| :.|         |:.|..|::
Mosquito   458 ESKNNWYSLRAYYLAKIVVELPTLILSSSVFFLIVY---YFTAQPFEWLRIGTFALVCLMFGWIS 519

  Fly   538 ----MSLSAVAAVGYGVFLSSLFESDKMASECAAPFDLIFLIFGGTYMNVD----TVPGLKYLSL 594
                :.|.::.:|...||:|.|.         ..|..|    |.|.::.:.    .|..|.|:|.
Mosquito   520 QMLGLLLGSLLSVQNSVFVSILI---------MVPASL----FSGFFVPLRDASVLVRPLLYVSF 571

  Fly   595 FFYSNEALMYKFW-IDIDNIDCP 616
            ..|:.|..::..: .|..::|||
Mosquito   572 VRYAFEGAVHAIYGFDRPDLDCP 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	73/267 (27%)
		3a01204	40..673	CDD:273361	157/673 (23%)
		ABC2_membrane	404..604	CDD:279410	55/264 (21%)
AgaP_AGAP008945	XP_319700.4	P-loop_NTPase	11..213	CDD:304359	73/267 (27%)
		3a01204	12..644	CDD:273361	157/673 (23%)
		ABC2_membrane	412..582	CDD:279410	41/186 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910