Protein Alignment bw and AgaP_AGAP008889

DIOPT Version :9

• Sequence 1: NP_001286769.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: XP_319635.4
• Gene: AgaP_AGAP008889 / 1279856
• VectorBaseID: AGAP008889
• Length: 656
• Species: Anopheles gambiae
• Alignment Length: 750
• Identity: 155/750 - (20%)
• Similarity: 267/750 - (35%)
• Gaps: 231/750 - (30%)

  Fly    48 ILQDASGHMKTGDLIAILGGSGAGKTTLLAAISQRLRGNLTGDVVLNGMAMERHQMTRISSFLPQ 112
            :|...||..::|:|.||:|.|||||::||..::......:.|.:..........   ::.|::.|
Mosquito     3 VLNGVSGRFQSGELTAIMGPSGAGKSSLLNILTGYTTHGVKGTLAFGSSGSTNR---KLCSYILQ 64

  Fly   113 FEINVKTFTAYEHLYFMSHFKMHRRTTKAEKRQRVADLLLAVGLRDAAH------TRIQQLSGGE 171
            .:.....||.:|.:......|:...:....::.|:.|.:|     |..|      ||...||||:
Mosquito    65 EDYLQPLFTVHEIMLMACDLKVSSDSLNRSEKLRLVDKIL-----DTLHLSYCKQTRCGSLSGGQ 124

  Fly   172 RKRLSLAEELITDPIFLFCDEPTTGLDSFSAYSVIKTLRHLCTRRRIAKHSLNQVYGEDSFETPS 236
            |||||:|.|||.:|..||.|||||||||.|:...||.|:.|....|
Mosquito   125 RKRLSIALELIDNPPILFLDEPTTGLDSSSSLYTIKLLQGLAREGR------------------- 170

  Fly   237 GESSASGSGSKSIEMEVVAESHESLLQTMRELPALGVLSNSPNGTHKKAAICSIHQPTSDIFELF 301
                                                            ..:|:||||::.::|:|
Mosquito   171 ------------------------------------------------TIVCTIHQPSATVYEMF 187

  Fly   302 THIILMDGGRIVYQGRTEQAAKFFTDLGYELPLNCNPADF--YLKTL------------------ 346
            .|:.::..|..||||.......:...:|...|...|.||:  :|:.|
Mosquito   188 DHVYVLAEGHCVYQGSALNTVPYLRSVGLHCPAYHNAADYCKFLRCLCVCVLYFLIHPLPFFQQC 252

  Fly   347 ----------------------------------------------------------------- 346
                                                                             
Mosquito   253 WRSPTRSTATLPKRLPKPPPIRAGDWPRSSTGWAVVVVVVECRPHYPPVRRPTTAITTCRLPGPP 317

  Fly   347 ----------------ADKEGKENAGAVLRAKYEHETDGLYSGSWL--LARSYSG-DYL----KH 388
                            |.::|.......:|.....:.|.....|.:  |.:|..| :|:    .|
Mosquito   318 EGSGGGRTASRPGGPAARQDGGPEPAPTVRVCQTVDPDEALQHSAVPGLGKSLGGKEYVPKPSTH 382

  Fly   389 VQN-------FKKIRWIYQVYL-LMVRFMTEDLRNIRSGLIAFGFFMITAVTLSLMYSGIGGLTQ 445
            ...       |:::|.....:| |.|.                   ::.|:.:.|::...|....
Mosquito   383 FHENFPPLPPFRRLRLQTVTHLKLFVH-------------------IVCAIVIGLLFGDSGINAT 428

  Fly   446 RTVQDVGGSIFMLSNEMIFTFSYGVTYIFPAALPIIRREVGEGTYSLSAYYVALVLSFVPVAFFK 510
            :::.:|...:..:......|...||.. :|..:.|:::|.....|.:..|:||.:|:.:||..|.
Mosquito   429 KSISNVASFMVHILYLWYTTVMPGVLK-YPYEMNILKKESFNRWYKIRTYFVASMLTSLPVQIFF 492

  Fly   511 GYVFLSVIYASIYYTRGFLLYLSMGFLMSLSAVAAVGYGVFLSSLFESDKMASECAAPFDLIFLI 575
            ..|:.:::||..|.......||....::.|:.:.|.|:|:||.: |.::...:...|.......:
Mosquito   493 AIVYATIVYAMTYQPCELERYLMFTAVLVLNTIVADGFGLFLGT-FLNEINGTFIGAIMTCFMFV 556

  Fly   576 FGG-----TYMNVDTVPGLKYLSLFFYSNEALMYKFWIDI-DNIDCPVNEDHPC--IKTGVEVLQ 632
            |.|     ::|: |.:.|:.|||...||.|||:...:.|. .::.||.:|.: |  :|....:.:
Mosquito   557 FCGFLIMFSHMS-DAMRGISYLSSHRYSFEALVLTAYDDSRSDLVCPKDEMY-CHYVKANTIMRE 619

  Fly   633 QGSYRNADYTYWLDCFSLVVVAVIFHIVSFGLVRR 667
            .|....   .|..:..:|||..|...:|.|..::|
Mosquito   620 LGVVSG---NYLFNVVTLVVHFVAIKVVGFWTLKR 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	71/273 (26%)
		3a01204	40..673	CDD:273361	154/749 (21%)
		ABC2_membrane	404..604	CDD:279410	47/204 (23%)
AgaP_AGAP008889	XP_319635.4	3a01204	1..654	CDD:273361	154/749 (21%)
		ABCG_EPDR	1..202	CDD:213180	71/273 (26%)
		ABC2_membrane	394..588	CDD:279410	48/215 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900