Protein Alignment bw and AgaP_AGAP000506

DIOPT Version :9

• Sequence 1: NP_001286769.1
• Gene: bw / 37724
• FlyBaseID: FBgn0000241
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: XP_310585.4
• Gene: AgaP_AGAP000506 / 1271735
• VectorBaseID: AGAP000506
• Length: 678
• Species: Anopheles gambiae
• Alignment Length: 704
• Identity: 207/704 - (29%)
• Similarity: 316/704 - (44%)
• Gaps: 159/704 - (22%)

  Fly     3 ESGGSSGQGGPSLCLEWKQLNYYVPDQEQSNYSFWNECRKKRELRILQDASGHMKTGDLIAILGG 67
            :.||..|.|||.                        .|.:....||:.:.||.:..|.|||::|.
Mosquito    81 KGGGCGGGGGPP------------------------GCHRPTIKRIINNVSGAVTPGTLIALMGS 121

  Fly    68 SGAGKTTLLAAISQRLRGN--LTGDVVLNGMAMERHQMTRISSFLPQFEINVKTFTAYEHLYFMS 130
            |||.|:||::|::.|....  :.||:::||..:..: |.|:|.|:.|.::.|.:.|.:||:|||:
Mosquito   122 SGAAKSTLMSALAYRTPPGTVVQGDILVNGQPVGPY-MYRLSGFVHQDDLFVGSLTVHEHMYFMA 185

  Fly   131 HFKMHRRTTKAEKRQRVADLLLAVGLRDAAHTRI------QQLSGGERKRLSLAEELITDPIFLF 189
            ..::.||.......|.:.|||..|||...|.|||      :.|||||:|||:.|.||:|.|..||
Mosquito   186 KLRLDRRVGHRAIDQTIRDLLERVGLARCAGTRIGEAGDGKMLSGGEKKRLAFATELLTKPTLLF 250

  Fly   190 CDEPTTGLDSFSAYSVIKTLRHLCTRRRIAKHSLNQVYGEDSFETPSGESSASGSGSKSIEMEVV 254
            ||||||||||:.|.:::.||:.|..|
Mosquito   251 CDEPTTGLDSYGAQALVSTLQQLARR--------------------------------------- 276

  Fly   255 AESHESLLQTMRELPALGVLSNSPNGTHKKAAICSIHQPTSDIFELFTHIILMDGGRIVYQGRTE 319
                                     ||   |.||:||||:|.:|.:|..::|:..||:.|.||..
Mosquito   277 -------------------------GT---AIICTIHQPSSQLFSMFDQVMLLAEGRVAYAGRPH 313

  Fly   320 QAAKFFTDLGYELPLNCNPADFYLKTLADKEGKENAGAVLRAKYEHETDGLYSGSWLLAR----- 379
            :|..||...|:..|.:.|||::.:..||...|.|.|.    .:..|....|::.|....:
Mosquito   314 EALAFFARHGHACPPSYNPAEYLIGALATAPGYEQAS----QRAAHRLCDLFAVSEAAGQRDVLI 374

  Fly   380 ------SYSGDY-----LKHVQNFKKIRWI-------YQVYLLMVRFMT-EDLRNIRSGLIAFGF 425
                  :.||||     ::|:..  :..|:       |:..|.:||..| :.||.::.
Mosquito   375 NLEVHMAESGDYRVTDEVQHLAG--RPHWLHTTAWLTYRALLTVVRDPTVQYLRLLQK------- 430

  Fly   426 FMITAVTLSLMYSGIGGLTQRTVQDVGGSIFMLSNEMIFTFSYGVTYIFPAALPIIRREVGEGTY 490
             :..|:...|.::|....||..||...|.:|:|.:|..||..|.|..:||...|:..||...|.|
Mosquito   431 -IAIALMAGLCFTGAIEPTQLGVQATQGLLFILISENTFTPMYAVLAVFPETFPLFMRETKNGLY 494

  Fly   491 SLSAYYVALVLSFVPVAFFKGYVFLSVIYASIYYTRGFLLYLSMGFLMSLSAVAAV-----GYGV 550
            ..|.||||.|.:.:|     |.|...:::..|.|....|......||::.:|...|     ..|.
Mosquito   495 HPSQYYVANVAAMLP-----GLVLEPLVFVLIAYWLAALRPTLHAFLVTAAAATLVMNVSTACGC 554

  Fly   551 FLSSLFESDKMASECAAPFDLIFLIFGGTYMNVDTVPG----LKYLSLFFYSNEALMYKFWIDID 611
            |.|:.|.|..:|.....|||.|.:|..|.:::::|:|.    |.|:|...|:|||:....|..:.
Mosquito   555 FFSAAFNSLPLAMAYLVPFDYILMITSGVFIHLNTMPAATRWLPYISWMMYANEAMSIAQWEGVS 619

  Fly   612 NIDCPVNEDH-PCIKTGVEVLQQGSYRNADY--TYWLDCFSLVVVAVIFHIVSF 662
            ||.||..:|. ||::||.|||:..|:.....  ..|    ::|::...||::.:
Mosquito   620 NITCPAVDDKLPCLRTGGEVLEHYSFSETHLAPNLW----AMVLLYFGFHLLGY 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bw	NP_001286769.1	P-loop_NTPase	31..316	CDD:304359	93/292 (32%)
		3a01204	40..673	CDD:273361	201/667 (30%)
		ABC2_membrane	404..604	CDD:279410	64/209 (31%)
AgaP_AGAP000506	XP_310585.4	ABCG_EPDR	63..310	CDD:213180	99/320 (31%)
		3a01204	64..678	CDD:273361	207/704 (29%)
		ABC2_membrane	408..613	CDD:279410	66/217 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820